Article Summary
March 3, 2020
Community Transmission of Severe Acute Respiratory Syndrome Coronavirus 2, Shenzhen, China, 2020
In Shenzhen, China, community and family transmission of COVID-19 are outpacing transmission from individuals with known exposures or travel history to Hubei province. An increase in pediatric cases may be attributable to more exposure opportunities due to community transmission. The authors discuss important strategies for reducing transmission, including early screening, diagnosis, isolation, and treatment, in…
March 2, 2020
Coronavirus Disease 2019: Coronaviruses and Blood Safety
With concerns around asymptomatic transmission, authors offer recommendations for blood safety in areas with known spread. They also provide inactivation methods for coronaviruses in blood products and laboratory tissue culture. Chang et al. (Feb 21, 2020) Coronavirus Disease 2019: Coronaviruses and Blood Safety. Transfusion Medicine Review 29, 203s. https://doi.org/10.1016/j.tmrv.2020.02.003
The neuroinvasive potential of SARS-CoV2 may be at least partially responsible for the respiratory failure of COVID-19 patients
Another study examining the neurological effects of COVID-19 suggests that these may be partially responsible for respiratory failure among patients. Li et al. (Feb 27, 2020). The neuroinvasive potential of SARS-CoV2 may be at least partially responsible for the respiratory failure of COVID-19 patients. J Med Virol. https://doi.org/10.1002/jmv.25728
A Case Series of children with 2019 novel coronavirus infection: clinical and epidemiological features
Authors describe a case series of 10 pediatric COVID-19 patients in China. Epidemiologic characteristics of each case, including potential sources of infection, and detailed clinical features are provided. While symptoms were generally mild, prolonged viral shedding was observed in respiratory and fecal samples. Jiehao et al. (Feb 28, 2020) A Case Series of children with…
Effects of “Fangcang, Huoshenshan, and Leishenshan” Makeshift Hospitals and Temperature on the Mortality of COVID-19
The establishment of makeshift hospitals and rising ambient temperatures appear associated with improved survival among COVID-19 patients in Hubei. Cai et al. (Feb 29, 2020). Effects of “Fangcang, Huoshenshan, and Leishenshan” Makeshift Hospitals and Temperature on the Mortality of COVID-19. Pre-print downloaded Feb 29 from https://doi.org/10.1101/2020.02.26.20028472
Heart injury signs are associated with higher and earlier mortality in coronavirus disease 2019 (COVID-19)
COVID-19 patients who present with signs of heart injury during the course of their illness may be at higher risk of death than other patients and should be managed carefully. Wu et al. (Feb 29, 2020). Heart injury signs are associated with higher and earlier mortality in coronavirus disease 2019 (COVID-19). Pre-print downloaded Feb 29…
Clinical characteristics of 36 non-survivors with COVID-19 in Wuhan, China
A case series of 36 COVID-19 fatalities yields similar findings to prior research indicating that males with comorbidities are commonly among those who die of the disease. Median time from symptom onset to acute respiratory distress syndrome among these deaths was 11 days, while gradually decreasing lymphocytes and increased inflammation biomarkers were also common. Huang…
Evaluation of the clinical characteristics of suspected or confirmed cases of COVID-19 during home care with isolation: A new retrospective analysis based on O2O
48 confirmed and suspected COVID-19 patients who underwent home isolation without hospitalization in China were monitored via an online platform for symptoms. The authors conclude that frequent laboratory samples and physical examination are not necessary for monitoring patients with mild symptoms. Xu et al. (Feb 29, 2020). Evaluation of the clinical characteristics of suspected or…
Clinical trial analysis of 2019-nCoV therapy registered in China
Zhang et al summarize clinical trials for potential COVID-19 treatment options. Zhang et al. (Feb 28, 2020) Clinical trial analysis of 2019-nCoV therapy registered in China. J Med Virol. https://doi.org/10.1002/jmv.25733
A Well Infant with Coronavirus Disease 2019 (COVID-19) with High Viral Load
An asymptomatic 6-month old infant was hospitalized with COVID-19 and had positive nasopharyngeal swabs 16 days after admission. The case highlights potential flaws in current symptom-centric case definitions, especially in infants. Kam et al. (Feb 28, 2020). A Well Infant with Coronavirus Disease 2019 (COVID-19) with High Viral Load. Clin Infect Dis. https://doi.org/10.1093/cid/ciaa201
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