Article Summary
February 7, 2020
A database resource for Genome-wide dynamics analysis of Coronaviruses on a historical and global scale
Researchers developed an online coronavirus databases to facilitate genomics and protemics analysis. This publicly accessible database is free to access at: http://covdb.popgenetics.net Zhu et al. (Feb 7, 2020). A database resource for Genome-wide dynamics analysis of Coronaviruses on a historical and global scale. Pre Print downloaded Feb 7 from: https://www.biorxiv.org/content/10.1101/2020.02.05.920009v1
Diagnosis and treatment of 2019 novel coronavirus infection in children: a pressing issue
Clinical features of 28 pediatric 2019-nCoV patients are described. Age range 1 month – 17 years, all associated with family clusters. Several patients had no obvious clinical symptoms but were identified as part of close contact screening. Most had mild symptoms without fever or pneumonia. No severe cases or deaths have been reported. Shen and…
Diagnosis and treatment recommendations for pediatric respiratory infection caused by the 2019 novel coronavirus
Researchers and clinicians in China and Zhejiang Province developed recommendations for the diagnosis and treatment of 2019-nCoV in children. They provide child-specific diagnostic criteria and considerations for newborns. Clinical presentation appears similar to adults: Pediatric patients generally present with fever, fatigue, and cough, and sometimes with congestion, runny nose, expectoration, diarrhea, headache, and other symptoms. …
Novel coronavirus infection during the 2019–2020 epidemic: preparing intensive care units—the experience in Sichuan Province, China
ICU physicians in Sichuan Province developed a preparedness and response plan for handling severe cases of 2019-nCoV. They provide metrics for assessing patients and ensuring the health and safety of clinical and hospital staff. Liao et al. (Feb 5, 2020). Novel coronavirus infection during the 2019–2020 epidemic: preparing intensive care units—the experience in Sichuan Province,…
Emerging Coronavirus 2019-nCoV Pneumonia
Song et al. provide an overview of imaging results for 51 confirmed 2019-nCoV cases. Song et al. (Feb 6, 2020). Emerging Coronavirus 2019-nCoV Pneumonia. Radiology. https://pubs.rsna.org/doi/10.1148/radiol.2020200274
Imaging changes in patients with 2019-nCov
Changes in chest CT from initial diagnosis with 2019-nCoV to subsequent imaging are described for patients at one hospital. Pan and Guan (Feb 6, 2020). Imaging changes in patients with 2019-nCov. European Radiology. https://doi.org/10.1007/s00330-020-06713-z
2019-nCoV epidemic: what about pregnancies?
This brief correspondence provides some considerations for 2019-nCov infection, diagnosis, and treatment during pregnancy based on experiences with MERS-CoV and SARS-CoV. Favre et al. (Feb 6, 2020). 2019-nCoV epidemic: what about pregnancies? The Lancet. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30311-1/fulltext
Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China
Clinical characteristics of 138 hospitalized patients with confirmed 2019-nCoV at a single hospital are described, comparing across ICU status. The symptom profile is comparable to other case series reports. As expected, comorbidities, complications, and various treatment procedures were more common among ICU patients, who were also older on average than non-ICU patients. Wang et al….
Persons Evaluated for 2019 Novel Coronavirus — United States, January 2020
CDC compiled information from ~650 state reports and inquiries regarding persons under investigation (PUI) for 2019-nCov through Jan 31. Clinical characteristics, epidemiologic risk classification, setting where patient was identified, and testing results are presented. Of the 210 people tested, 11 (5%) tested positive for 2019-nCoV and 9 of these had travel history to Wuhan. The…
Epidemic doubling time of the 2019 novel coronavirus outbreak by province in mainland China
Researchers estimated the epidemic doubling time of the outbreak by province in mainland China. From Jan 20 – Feb 2, doubling time ranged from 1.0 day to 3.3 days, with Hubei estimated at 2.4 days. Social distancing measures appear to have been successful in slowing but not stopping epidemic growth. Muniz-Rodriguez et al. (Feb 6,…
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