Alliance for Pandemic Preparedness

COVID-19 Literature Situation Report

COVID-19 Literature Situation Report is a daily (M-F) newsletter that provides a succinct summary of the latest scientific literature related to the COVID-19 pandemic.

The scientific literature on COVID-19 is rapidly evolving and these articles were selected for review based on their relevance to Washington State decision making around COVID-19 response efforts. Included in these Lit Reps are some manuscripts that have been made available online as pre-prints but have not yet undergone peer review. Please be aware of this when reviewing articles included in the Lit Reps.

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October 23, 2020

COVID-19 LITERATURE SITUATION REPORT OCT. 23, 2020

Universal mask wearing in the United States could save an additional 129,574 lives from September 22 through the end of February 2021, or 85% mask use could save an additional 95,814 lives when compared to a reference scenario in a model from IHME.


October 22, 2020

COVID-19 LITERATURE SITUATION REPORT OCT. 22, 2020

Only 1 to 6 cases of hospital-acquired SARS-CoV-2 infection at UW Medicine were reported from April 2 to May 14, corresponding to a relatively low incidence of 0.8 to 5 cases per 10,000 patient days. More


October 21, 2020

COVID-19 LITERATURE SITUATION REPORT OCT. 21, 2020

The scientific literature on COVID-19 is rapidly evolving and these articles were selected for review based on their relevance to Washington State decision making around COVID-19 response efforts. Included in these Lit Reps are some manuscripts that have been made available online as pre-prints but have not yet undergone peer review. Please be aware of…


October 20, 2020

COVID-19 LITERATURE SITUATION REPORT OCT. 20, 2020

Despite early enthusiasm for monoclonal antibodies directed against IL-6 (tocilizumab), two randomized, open-label trials did not demonstrate substantial clinical benefit, both reporting no effect on 28-day mortality. These findings, combined with two previously reported industry sponsored trials by the manufacturer of tocilizumab, indicate that tocilizumab may not be as efficacious as suggested by early observational data.


October 19, 2020

COVID-19 LITERATURE SITUATION REPORT OCT. 19, 2020

During the first wave of the COVID-19 pandemic in Hong Kong, there was a longer time to diagnosis among people living in public rental houses and in areas with lower educational attainment. In contrast, no such association was observed during the second wave when surveillance measures were enhanced.


October 16, 2020

COVID-19 LITERATURE SITUATION REPORT OCT. 16, 2020

Children who were infected with SARS-CoV-2 at an overnight camp in Georgia in June transmitted the virus to 9% of their household contacts, with 10% of the adult secondary cases requiring hospitalization.


October 15, 2020

COVID-19 LITERATURE SITUATION REPORT OCT. 15, 2020

In an ongoing randomized controlled phase 1 trial of RNA-vaccine candidates BNT162b1 and BNT162b2, both vaccine candidates elicited similar SARS-CoV-2 neutralizing titers. BNT162b2 was associated with a lower incidence and severity of systemic reactions than BNT162b1, particularly among older adults.


October 14, 2020

COVID-19 Literature Situation Report Oct. 14, 2020

Novel Coronavirus SARS-CoV-2

Transmission events from college-aged individuals to older individuals at nursing facilities resulted in two deaths, according to genomic sequence analysis of a COVID-19 outbreak following the reopening of colleges in La Crosse County, Wisconsin.


October 13, 2020

COVID-19 Literature Situation Report Oct. 13, 2020

A man from Nevada was reported as the first case of SARS-CoV-2 reinfection in North America, with genomic evidence supporting that the first infection in May and the second in June were from separate occasions. Symptoms were more severe during the second infection. More


October 12, 2020

COVID-19 Literature Situation Report Oct. 12, 2020

More than 815,000 deaths due to COVID-19 globally could be prevented by universal mask use between August 26, 2020 and January 1, 2021, based on recent IHME projections



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