COVID-19 Literature Situation Report
COVID-19 Literature Situation Report is a daily (M-F) newsletter that provides a succinct summary of the latest scientific literature related to the COVID-19 pandemic.
The scientific literature on COVID-19 is rapidly evolving and these articles were selected for review based on their relevance to Washington State decision making around COVID-19 response efforts. Included in these Lit Reps are some manuscripts that have been made available online as pre-prints but have not yet undergone peer review. Please be aware of this when reviewing articles included in the Lit Reps.
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May 4, 2020
COVID-19 Literature Situation Report May 4, 2020
Repeated universal testing (for instance, via mailed home testing kits) with isolation of infectious individuals can reduce transmission sufficiently to halt the epidemic, even with a false negative test rate of up to 15%
May 1, 2020
COVID-19 Literature Situation Report May 1, 2020
Detection of SARS-CoV-2 RNA in the blood is strongly associated with severe disease (ICU hospitalization 32% v. 14%; mechanical ventilation 21% v. 4%) and increased mortality among COVID-19 patients (14% v. 0%) compared to patients without detectable RNA.
April 30, 2020
COVID-19 Literature Situation Report April 30, 2020
Findings from a systematic review do not support claims that most SARS-CoV-2 infections are asymptomatic, estimating that only about 29% of infections remain asymptomatic throughout the course of infection.
April 29, 2020
COVID-19 Literature Situation Report April 29, 2020
Waste water based epidemiology is a sensitive tool that can be used to monitor spatial and temporal trends of SARS-CoV-2 virus circulation in the population.
April 28, 2020
COVID-19 Literature Situation Report April 28, 2020
Barkan et al compares various exit strategy building blocks and measures to mitigate the current SARS-CoV-2 pandemic based on computerized simulations, finding significant differences in suppression among strategies with seemingly similar cost.
April 27, 2020
COVID-19 Literature Situation Report April 27, 2020
Vertical transmission of SARS-CoV-2 infection from mothers affected by COVID-19 during the last days of pregnancy is possible but relatively infrequent.
April 24, 2020
COVID-19 Literature Situation Report April 24, 2020
The downward trend of IgG during recovery may indicate limited duration of acquired immune protection
April 23, 2020
COVID-19 Literature Situation Report April 23, 2020
Modeling studies continue to highlight the dangers of lifting or relaxing social distancing policies too soon, and suggest a longer-term initial period of restrictive social distancing coupled with a gradual reduction in the severity of social distancing as being more effective.
April 22, 2020
COVID-19 Literature Situation Report April 22, 2020
Models suggest using controlled avalanche strategy to achieve herd immunity faster and with lower mortality rates. This strategy reduces overall mortality and ICU admissions by 43 and 62% respectively.
April 21, 2020
COVID-19 Literature Situation Report April 21, 2020
Multiple studies evaluate the effectiveness of non-pharmaceutical interventions. While border closures, quarantine policies and business closures were generally associated with reduced SARS-CoV-2 (and, in one study, influenza) transmission, school closures were noted as the least effective intervention.
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