Alliance for Pandemic Preparedness

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Tag: adverse events

June 7, 2021

Adverse Events Following MRNA SARS-CoV-2 Vaccination among U.S. Nursing Home Residents

No major safety problems were detected following the first or second dose of either of the two mRNA SARS-CoV-2 vaccines in a study of electronic health records from US nursing home residents (n = 8,553) between December 18, 2020 and March 7, 2021. The analysis of pre-specified adverse events did not detect statistical signals for…

June 3, 2021

Efficacy and Safety of COVID-19 Vaccines: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

In a systematic review and meta-analysis of 25 randomized trials assessing safety and efficacy of COVID-19 vaccines, mRNA-based (e.g., Pfizer-BioNTech and Moderna) and adenovirus-vectored (e.g., Oxford-AstraZeneca, Johnson & Johnson, Sputnik V) vaccines had the highest efficacy in phase 2/3 trials (94.6% and 80.2%, respectively). The mRNA-based vaccines had the highest level of side effects reported,…