Alliance for Pandemic Preparedness

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Tag: antibodies


October 21, 2020

Seroprevalence of Anti‐SARS‐CoV‐2 Antibodies in COVID‐19 Patients and Healthy Volunteers up to Six Months Post Disease Onset

A study among patients who tested positive for SARS-CoV-2 by PCR reported an increase in the detection of antibodies against the SARS-CoV-2 receptor binding domain (RBD) and spike protein using ELISA rapidly during the acute phase after infection, with a peak in detection around week 3. The detection of IgG antibodies remained robust, with confirmed…


October 7, 2020

Antibody Reactivity to SARS-CoV-2 in Adults from the Vancouver Metropolitan Area Canada

[Pre-print, not peer-reviewed] A substantial proportion of individuals who lacked serological evidence of SARS-CoV-2 exposure showed antibody reactivity against SARS-CoV-2 antigens, possibly due to cross-reactivity of antibodies against other coronaviruses. Among 276 adults tested for SARS-CoV-2 antibodies during the second wave of the COVID-19 pandemic in Vancouver, Canada (May 17-June 19, 2020), 3 participants tested…


September 14, 2020

SARS-CoV-2 Antibody Prevalence and Association with Routine Laboratory Values in a Life Insurance Applicant Population

[Preprint, not peer-reviewed] Testing for SARS-CoV-2 antibodies indicates that the total number of SARS-CoV-2 infections in the US is 3.8-times higher than the total number of cases reported to the CDC. This estimate is based on a seropositivity rate of 3% among 50,130 consecutive life insurance applicants, which would correspond to 6.98 million SARS-CoV-2 infections…



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