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Tag: clinical characteristics
May 18, 2021
Characteristics and Outcomes Among US Patients Hospitalized for Ischemic Stroke Before vs During the COVID-19 Pandemic
Stroke patients with comorbid COVID-19 (n=5,517) had a 5-fold higher risk of in-hospital death compared to stroke patients prior to the pandemic (n=165,912), according to an analysis of hospital records of patients admitted for ischemic stroke between January 2019 to December 2020. Compared to stroke patients prior to the pandemic and non-COVID-19 patients during the…
Serial Interval of COVID-19 and the Effect of Variant B.1.1.7 Analyses from a Prospective Community Cohort Study (Virus Watch)
[Pre-print, not peer-reviewed] The mean interval between exposure to COVID-19 and the development of symptoms was 3.2 days, according to an analysis of 186 likely infector-infectee pairs in England and Wales. The mean serial interval in individuals belonging to households in regions and belonging to study weeks classified as having a high percentage of infections…
May 17, 2021
A Retrospective Cohort Study of 12,306 Pediatric COVID-19 Patients in the United States
A retrospective cohort study found that among 12,306 pediatric patients with lab-confirmed COVID-19 in the US, 5% were hospitalized, 18% needed critical care services and 4% required mechanical ventilation. 14% experienced gastrointestinal symptoms, 8% had dermatological symptoms (rash), 5% had headache, and 19% had other symptoms (fever, malaise, myalgia, arthralgia and altered smell or taste)….
May 14, 2021
Comparison and Impact of COVID-19 for Patients with Cancer: A Survival Analysis of Fatality Rate Controlling for Age, Sex and Cancer Type
A survival analysis of UK cancer patients (N=4,606) found that those with a SARS-CoV-2 diagnosis between March-October 2020 had a higher risk of death compared to patients without SARS-CoV-2. The risk of death within 21 days post SARS-CoV-2 detection was over 10-fold higher than among those without SARS-CoV-2 infection in patients with melanoma, hematological malignancies,…
May 12, 2021
Evolution of COVID-19 Symptoms during the First 9 Months after Illness Onset
[Pre-print, not peer-reviewed] In a cohort of COVID-19 patients from the Netherlands (n=301) 82% of patients recovering from severe/critical disease reported at least one persistent symptom 12 weeks after illness onset, compared to 33% and 64% among those recovering from mild to moderate disease, respectively. At nine months after illness onset, 42% of participants continued…
Trends over Time in the Risk of Adverse Outcomes among Patients with SARS-CoV-2 Infection
In the 30 days following a positive SARS-CoV-2 test, a decline in hospitalization (44% to 16%) and death (20% to 5%) was observed between February and July 2020 in a cohort of enrollees in the US Veterans Affairs healthcare system (n=55,952). Similar trends were also observed for 30-day incidence for ICU admission and mechanical ventilation….
May 11, 2021
Severe COVID-19 in People with Type 1 and Type 2 Diabetes in Sweden: A Nationwide Retrospective Cohort Study
Type 2 diabetes was associated with increased risk of COVID-19-related hospitalization (HR=2.22), admission to ICU (HR=2.49), and death (HR=2.19) in a nationwide study in Sweden that compared adult patients with type 2 diabetes (n=44,639) to age- and sex-matched controls. Risks for COVID-19 related outcomes remained independently associated with type 2 diabetes after further adjustment for…
Characteristics of Patients Discharged and Readmitted after COVID-19 Hospitalisation within a Large Integrated Health System in the United States
The 30-day readmission rate for patients admitted to hospital with COVID-19 among patients who belong to an integrated healthcare system (Kaiser Permanente) was 8% (n=166) in a retrospective cohort of 2,180 patients between April to July 2020. 58% of readmissions were respiratory-related and occurred a median of 5 days after discharge. Chronic pulmonary disease and…
Global Incidence of Neurological Manifestations Among Patients Hospitalized With COVID-19—A Report for the GCS-NeuroCOVID Consortium and the ENERGY Consortium
Neurological manifestations were found in 82% of patients hospitalized with COVID-19 in a cohort study across 2 consortia of patients from 13 countries (n=3,744). The most common self-reported symptoms included headache (37%) and loss of smell or taste (26%), while the most prevalent neurological signs and/or syndromes were acute encephalopathy (49%), coma (17%), and stroke…
Cerebral Venous Thrombosis and Portal Vein Thrombosis a Retrospective Cohort Study of 537913 COVID-19 Cases
[Pre-print, not peer-reviewed] Risk of diagnosis for cerebral venous thrombosis (CVT) and portal vein thrombosis (PVT) within 2 weeks of a COVID-19 diagnosis was 6.6-fold higher and 7.4-fold higher, respectively, compared to receiving a COVID-19 mRNA vaccine according to a retrospective study of administrative data in the US. Researchers compared patients with a COVID-19 diagnosis…
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