Alliance for Pandemic Preparedness

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Tag: health care setting


June 9, 2021

Accuracy of ICD-10 Diagnostic Codes to Identify COVID-19 Among Hospitalized Patients

The ICD-10 Diagnostic Code for COVID-19 (U07.1) had an overall sensitivity of 49% and specificity of 99% compared to the gold standard of a positive PCR test among 2,210 PCR-positive patients discharged between April and July 2020 across the Mass General Brigham health system in Boston, Massachusetts. Specificity was consistently high, but sensitivity varied and…


May 25, 2021

The Efficacy of UV Light-Emitting Technology against Coronaviruses: A Systematic Review

Complete inactivation of coronaviruses on surfaces and in aerosols required at least 15 minutes within a maximum distance from the UV emitter up to 1 meter, according to a systematic review of 18 studies reporting on the efficacy of UV technologies against coronaviruses (n=6 against SARS-CoV-2). The authors noted significant heterogeneity among the studies in…


May 13, 2021

Evaluation of Healthcare Personnel Exposures to Patients with SARS-CoV-2 Associated with Personal Protective Equipment Use

Lack of eye protection during the care of a COVID-19 patient was associated with test positivity for SARS-CoV-2 infection (RR=10) among 345 healthcare personnel (HCP) who sustained significant occupational exposure to COVID-19 patients in a tertiary care center in Minnesota from May to November 2020. While the most common reason for significant exposure was use…


April 19, 2021

COVID-19 Vaccination Preparedness Policies in U.S. Hospitals

A survey of US infectious disease physicians conducted between December 10, 2020 and January 2, 2021 found that 571 respondents (95%) reported that their facilities had a plan for determining which healthcare personnel (HCP) would be vaccinated first, with most prioritizing by unit (n = 226, 40%), job title or type of work (n =…


March 19, 2021

Variation in COVID-19 Mortality Across 117 US Hospitals in High- and Low-Burden Settings

Patients admitted to the most COVID-19 burdened hospitals had increased mortality compared to non-burdened hospitals, according to an analysis of patient admission data (n=14,226 patients) from an administrative database in April 2020. As of June 2020, 21% of all patients admitted with a COVID-19 diagnosis had died, and 1% remained hospitalized. At the hospital level,…


March 18, 2021

Hospital Policies During COVID-19

Visitor restriction policies varied significantly among the 70 largest US hospitals during the first 3 months of the COVID-19 pandemic. 65 of the hospitals had public-facing visitor restriction policies. While 49 of these policies had general “no-visitor” statements, 16 allowed at least 1 visitor to accompany all patients. 63 policies included exceptions to their visitor…


March 17, 2021

Nursing Home Characteristics Associated With Resident COVID-19 Morbidity in Communities With High Infection Rates

A study of residents of nursing homes (NHs) in communities with high SARS-CoV-2 infection rates found that NHs with more COVID-19 cases have residents who were older and had higher activities of daily living scores. Additionally, higher incidence NHs had a lower proportion of white residents and a higher proportion of residents who were insured…


Spread of a Variant SARS-CoV-2 in Long-Term Care Facilities in England

The proportion of SARS-CoV-2-positive samples that had an S gene target failure (suggestive of the B.1.1.7 strain) rose dramatically in late 2020 in the UK. The number and proportion of samples with S gene target failure increased from 12% to 60% between November 16 and December 13. By December 7, in South East England 57%…


March 12, 2021

COVID-19 Associated Pulmonary Aspergillosis in Mechanically Ventilated Patients

Among patients with COVID-19 who were receiving mechanical ventilation (n=396), patients with COVID-19 associated pulmonary aspergillosis (CAPA) had higher odds of worse disease outcome, required longer time to improvement and had an increased hazard of advancing disease severity compared to those without CAPA. Although there were no differences in mortality, patients with CAPA required significantly…


March 4, 2021

Alcohol Withdrawal Rates in Hospitalized Patients During the COVID-19 Pandemic

A cohort study in a hospital system in Delaware found an increase in rates of alcohol withdrawal (AW) during 2020 compared to 2019. Incidence in 2020 peaked at 1.8-fold higher than 2019 during the last 2 weeks of the stay-at-home order. AW rates remained elevated during the reopening period. Sharma et al. (Mar 3, 2021). Alcohol…



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