Alliance for Pandemic Preparedness

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Tag: health care setting


October 8, 2020

Risk of COVID-19 from Hospital Admission during the Pandemic

Nalleballe et al. report on 101,533 patients hospitalized for a non-COVID-19 related illness included in a global clinical research database representing 45 health care organizations. Only 44 (0.043%) tested positive for SARS-CoV-2 within 14 days of discharge between January and June 2020. These results suggest that risk of contracting SARS-CoV-2 during a hospital admission is…


October 7, 2020

State Actions and Shortages of Personal Protective Equipment and Staff in U.S. Nursing Homes

In June-July 2020, nearly half (47%) of nursing home facilities in the US reported a shortage of personal protective equipment (PPE) and/or staff needed to protect residents and staff from COVID‐19. Thirty percent of facilities reported at least one week of staffing shortage, and 28% reported at least one week of PPE shortage. These data were…


October 5, 2020

An Analysis of Changes in Emergency Department Visits After a State Declaration During the Time of COVID-19

An urban level 1 trauma center in Minnesota experienced a 35% decline in emergency department visits in 28 days following the state emergency declaration of COVID-19 on March 13, 2020, as compared with a similar period in 2019. Disproportionate declines were seen in visits by pediatric and older patients, women, and Medicare recipients, as well…


Seroprevalence of SARS-COV-2 Antibodies in Scottish Healthcare Workers

[Preprint, not peer-reviewed] Health and social care workers in a National Health Service facility in the UK (n=2,062) were three times more likely to test positive for anti-SARS-CoV-2 antibodies, compared to a group of controls (n=231) matched for age and sex to the general population of their community (OR=3.4, 95%CI 1.9-6.2). Dentists (26%), healthcare assistants…


September 25, 2020

Update: Characteristics of Health Care Personnel with COVID-19 — United States, February 12–July 16, 2020

Risk factors for mortality in health care personnel with COVID-19 were older age, male sex, Asian or Black self-identification, or the presence of an underlying comorbidity. Data from 100,570 laboratory confirmed and probable COVID-19 cases reported to CDC (February 12 – July 16, 2020) demonstrate that the median age of infected healthcare workers was 41…


September 23, 2020

Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Infection Among VA Healthcare System Employees Suggests Higher Risk of Infection When Exposed to SARS-CoV-2 Outside of the Work Environment

Among Veterans Affairs Healthcare System employees (n=2,900), those who reported direct contact with someone with COVID-19 outside of work were more likely to have SARS-CoV-2 antibodies. Facility-wide testing (June 8 to July 8, 2020) identified 5% of employees (n=1,476) of a Veterans Affairs Healthcare System tested positive for SARS-COV-2 IgG antibodies, of whom 29% reported…


September 22, 2020

Tracing Asymptomatic SARS-CoV-2 Carriers among 3674 Hospital Staff: A Cross-Sectional Survey

A single-center cross-sectional study of hospital staff in Wuhan, China tested all staff members who did not have clinical symptoms of COVID-19 (n=3,764) and found that 126 (3%) hospital staff had findings consistent with SARS-CoV-2 infection. These included 61 (2%) with anti-SARS-CoV-2 IgG antibodies, 37 (1%) with chest CT findings consistent with COVID-19, and 28…


Racial and Ethnic Disparities in COVID‐19 Infections and Deaths across U.S. Nursing Homes

A national study of 12,576 nursing homes indicated that nursing homes caring for disproportionately more racial/ethnic minority residents tended to have more new COVID-19 confirmed cases among their residents and staff and more new COVID-19 related deaths among residents. The number of weekly new COVID-19 confirmed cases among residents increased with higher nursing home proportion…


Hydroxychloroquine as Pre-Exposure Prophylaxis for COVID-19 in Healthcare Workers a Randomized Trial

Pre-exposure prophylaxis with hydroxychloroquine once or twice weekly did not significantly reduce laboratory-confirmed COVID-19 or COVID-19-compatible illness among healthcare workers in a randomized, double-blind, placebo-controlled clinical trial. For once weekly hydroxychloroquine prophylaxis, the hazard ratio was 0.72 (95%CI 0.44 to 1.16) and for twice weekly it was 0.74 (95%CI 0.46 to 1.19), as compared with…


Whole-Genome Sequencing to Track SARS-CoV-2 Transmission in Nosocomial Outbreaks

Whole virus genome viral sequencing of hospital-acquired cases of COVID-19 (March to April) in a tertiary referral center in Ireland indicated that the majority of the hospital-acquired cases occurred in patients highly dependent on nursing care. The authors conclude that this suggests that the likely route of transmission was by close contact or droplet, rather…



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