Alliance for Pandemic Preparedness

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Tag: non-pharm interventions


February 18, 2021

Reduction in Mobility and COVID-19 Transmission

Mobility data in 52 countries show that SARS-CoV-2 transmission decreased significantly with initial mobility reductions in 73% of countries. However, mobility explained a smaller proportion of transmission after relaxation of strict control measures in 80% of countries. In these countries, the predictive ability of mobility changed from a median R2 of 74% pre-relaxation to 30%…


Differences in Rapid Increases in County-Level COVID-19 Incidence by Implementation of Statewide Closures and Mask Mandates — United States, June 1–September 30, 2020

US county-level data from June to September 2020 show that counties in states that were closed for 0-59 days were more likely to experience rapidly increasing COVID-19 incidence (“rapid riser”) than those closed for >59 days, especially in non-metropolitan areas.  The probability of being a “rapid riser” county was 43% lower all among counties that…


February 13, 2021

The Effects of School Closures on SARS-CoV-2 among Parents and Teachers

Sweden kept schools open for in-person instruction for younger students (primary and lower-secondary) while closing schools for older students (upper-secondary), allowing for an evaluation of school closures on SARS-CoV-2 transmission. The rate of SARS-CoV-2 infection among lower-secondary teachers (who taught children age 14 to 16 in person) was twice as high (7.4 cases per 1,000)…


Operational Strategy for K-12 Schools through Phased Mitigation Executive Summary

The CDC released new guidelines for reopening K-12 schools for in-person learning, noting that evidence suggests that many K-12 schools that have strictly implemented mitigation strategies have been able to open safely for in-person instruction and remain open.  In addition to recommending specific disease prevention measures, the guidelines include the following statements: (1) K–12 schools…


February 11, 2021

Impact of COVID-19 Vaccination Program on Healthcare Worker Infections in an Academic Hospital

An academic hospital in Virginia reported a 25% decrease in health care worker (HCW) SARS-CoV-2 infections 6 days after beginning employee immunizations. Vaccines included both the Pfizer vaccine initiated on December 12, 2020 and the Moderna vaccine initiated on December 28, 2020. After achieving 60% vaccination coverage of the 1st dose, infections decreased by 50%….


COVID-19 Stats: Percentage of Middle and High School Students Aged 13–21 Years Attending In-Person Classes Who Reported Observing Fellow Students Wearing a Mask All the Time, by School Setting and Activity — United States, October 2020

Among a sample of 3,953 middle and high school students participating in a Falcon-CDC Foundation cross-sectional web panel survey in October 2020, approximately 65% reported that fellow students wore a mask “all the time” in the classroom, hallways, and stairwells. Lower frequencies were reported for other indoor settings, including school buses (42%), restrooms (40%), and…


Quantifying Population Contact Patterns in the United States during the COVID-19 Pandemic

Interpersonal contact in the San Francisco Bay area was reduced by 82% in March 2020 and by 60% in September 2020, compared to pre-pandemic levels, according to analysis of a series of self-reported contact surveys. The reduction in contact corresponded to a 73% reduction in Ro in March and a 36% reduction in September. While…


February 10, 2021

Maximizing Fit for Cloth and Medical Procedure Masks to Improve Performance and Reduce SARS-CoV-2 Transmission and Exposure, 2021

The CDC found that fitting a cloth mask over a medical procedure mask (double masking), and knotting the ear loops of a medical procedure mask, then tucking in and flattening the extra material near the face substantially improves the efficacy of masks. In simulated coughing experiments, the unknotted medical procedure mask blocked 42% of the…


February 8, 2021

The Impact of State Mask-Wearing Requirements on the Growth of COVID-19 Cases in the United States

An ecological study conducted from January-October 2020 found differences in median COVID-19 case rates (per 100,000) between states who adopted mask requirements “early” (before June 12, 15 states, rate = 5.7), “late” (after June 12, 19 states, rate = 5.59) or “never” (17 states, rate = 5.99). Models that controlled for confounders and interactions between…


February 5, 2021

Comparative cost-effectiveness of SARS-CoV-2 testing strategies in the USA: a modelling study

A mathematical model suggests that in communities where the SARS-CoV-2 is spreading rapidly, weekly testing coupled with a 2-week isolation period after a positive test is advisable. The authors assessed eight surveillance testing strategies that varied by testing frequency (from daily to monthly testing) and isolation period (1 or 2 weeks), compared with the status-quo…



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