Alliance for Pandemic Preparedness

Result for
Tag: other infections

June 3, 2021

Carbapenem-Resistant Klebsiella Pneumoniae Infections in ICU COVID-19 Patients—A Scoping Review

A literature review including 10 studies found evidence of hospital-based infection caused by the bacterium Klebsiella pneumoniae that was resistant to the carbapenem class of antibiotics among ICU patients with COVID-19 in 6 countries, ranging in prevalence from 0.35% to 53%. The majority of infected patients were male (85%), with a mean age of 61…

May 27, 2021

Early Bacterial Identification Among Intubated Patients with COVID-19 or Influenza Pneumonia: A European Multicenter Comparative Cohort Study

Bacterial identification within 48 hours after intubation in samples from patients with SARS-CoV-2 pneumonia (n=568) was associated with a 57% increase in risk for 28-day mortality in a multi-center cohort study in Europe. Compared to patients with influenza pneumonia (n=482), bacterial identification after intubation was less frequent in patients with SARS-CoV-2 pneumonia (10% vs 34%)….

April 13, 2021

Hospital-Acquired Infections among Adult Patients Admitted for COVID-19

26% of patients admitted for COVID-19 (n=963) to the Johns Hopkins Health System between March and May of 2020 had either a possible, probable, or confirmed hospital acquired infection (HAI).  Independent risk factors for development of probable/confirmed HAI included history of congestive heart failure, dexamethasone during hospitalization, ICU admission prior to HAI, and receipt of…

March 19, 2021

Bacterial Superinfections Among Persons With Coronavirus Disease 2019: A Comprehensive Review of Data From Postmortem Studies

Potential bacterial lung superinfections were found post-mortem in 32% of persons who died of COVID-19, with proven super-infection occurring in 8% of persons who died of COVID-19, based on a review of 75 published postmortem studies including post-mortem findings from 621 COVID-19 patients. Histopathologic findings in patients with potential lung infections demonstrated diffuse pneumonia was…

February 24, 2021

Invasive Pulmonary Aspergillosis in COVID-19 Critically Ill Patients: Results of a French Monocentric Cohort

The prevalence of invasive pulmonary aspergillosis (IPA) was not higher for mechanically ventilated COVID-19 patients compared to what has been described in other populations with acute respiratory distress syndrome (ARDS), according to a retrospective cohort study. The prevalence of IPA among non-immunocompromised patients in this cohort (n=52 patients) was 3.7%. Most (71%) of the patients…