Alliance for Pandemic Preparedness

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Tag: summarized as preprint

December 18, 2020

Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia

Tocilizumab reduced the rate of mechanical ventilation, but did not prevent deaths among hospitalized COVID-19 patients. In a randomized trial of patients hospitalized with COVID-19 pneumonia who were not receiving mechanical ventilation, tocilizumab reduced the likelihood of progression to the composite outcome of mechanical ventilation or death, but did not improve survival. The cumulative percentage…

November 4, 2020

SARS-CoV-2 Infections Among Children in the Biospecimens from Respiratory Virus-Exposed Kids (BRAVE Kids) Study

A prospective cohort study in North Carolina found that 77% of children and adolescents living with a close household contact infected with SARS-CoOV-2 had a positive SARS-COV2 PCR test. Hispanic ethnicity (OR=1.5) and having an infected sibling close contact (OR=1.7) were associated with increased infection risk. One or more symptoms were reported by 70% of…