Alliance for Pandemic Preparedness

Result for
Tag: washington

June 14, 2021

Comparison of Symptoms and RNA Levels in Children and Adults With SARS-CoV-2 Infection in the Community Setting

SARS-CoV-2 RNA levels, as determined by cycle threshold (Ct) values, were significantly higher in symptomatic compared to asymptomatic individuals, and no significant differences in RNA levels were detected between adults and children, according to results from a community-based cross-sectional study in King County, Washington. Among 555 SARS-CoV-2–positive participants, 47 of 123 children (38%) were asymptomatic…

June 10, 2021

Association of COVID-19 Vaccination Prioritization and Hospitalization among Older Washingtonians

Prioritization of individuals aged ≥65 years in Washington State for COVID-19 vaccination in January 2021 resulted in an estimated 434 fewer hospitalizations and 122 fewer deaths through March 2021 according to an analysis that compared actual age-specific COVID-19 hospitalization and fatality rates with a synthetic control group generated from a model based on age-specific COVID-19…

June 7, 2021

Slight Reduction in SARS-CoV-2 Exposure Viral Load Due to Masking Results in a Significant Reduction in Transmission with Widespread Implementation

A mathematical model fit to data from King County, Washington found that in a scenario where masks only lowered viral exposure by about 50%, they were still effective at controlling SARS-CoV-2 transmission, and moderately efficacious masks would reduce exposure viral load ten-fold among people who get infected despite masking in the era before vaccines were…

Early Epidemiological Evidence of Public Health Value of WA Notify a Smartphone-Based Exposure Notification Tool Modeling COVID-19 Cases Averted in Washington State

[Pre-print, not peer-reviewed] A study of the impact of Washington State’s exposure notification tool, WA Notify, in mitigating the spread of COVID-19 during the first four months of implementation found that based on an estimated COVID-19 case fatality of 1.4%, WA Notify saved 30-120 lives over this period. A model was run on a range…

May 28, 2021

Seroprevalence of SARS-CoV-2 Antibodies in Seattle, Washington: October 2019–April 2020

Residual clinical samples collected from 766 Seattle-area adults during October 2019 to April 2020 showed that anti-SARS-CoV-2 antibodies were not detected until mid-March 2020. Estimated antibody prevalence from March 5-April 1, 2020 was 1.2%, which was 11 times greater than the number of confirmed cases in King County, which includes Seattle, as of April 1….

May 26, 2021

Variants of Concern Are Overrepresented among Post-Vaccination Breakthrough Infections of SARS-CoV-2 in Washington State

[Pre-print, not peer-reviewed] All (n = 20) breakthrough infections detected among fully vaccinated University of Washington healthcare workers involved a variant of concern, compared to a background rate of 68% of community cases being caused by a variant of concern across WA state during the same time period (N=5,174).  Additionally, variants that have been reported…

May 25, 2021

Socioeconomic and Racial Inequities in Breast Cancer Screening During the COVID-19 Pandemic in Washington State

Breast cancer screening declined by 49% in Washington State during the COVID-19 pandemic compared to pre-pandemic screening, according to an analysis of completed mammograms within a large non-profit community health care system. 55,678 screenings were conducted between April to December 2019 whereas only 27,522 screenings occurred during the same period in 2020. Greater declines in…

May 19, 2021

Rapidly Emerging SARS-CoV-2 B.1.1.7 Sub-Lineage in the United States of America with Spike Protein D178H and Membrane Protein V70L Mutations

[Pre-print, not peer-reviewed] Genomic surveillance of SARS-CoV-2 cases identified an expanding US-specific sub-lineage of the B.1.1.7 variant. This sub-lineage is characterized with sequential acquisition of a membrane protein mutation, V20L, in November 2020 and a spike mutation, D178H, in early February 2021. The proportion of B.1.1.7 isolates in the US belonging to this sub-lineage increased…

May 11, 2021

Decreases in Reported Sexually Transmitted Infections during the Time of COVID-19 in King County, WA

Reported cases of gonorrhea and syphilis decreased by 5-22% in King County, Washington from January to July 2020 compared to January to July 2019. Mean weekly case counts of gonorrhea, male urethral gonorrhea, and early latent syphilis decreased during statewide lockdowns in late March, but returned to pre-lockdown levels after reopening in June. The authors…

April 29, 2021

COVID-19 Outbreak Among Farmworkers — Okanogan County, Washington, May–August 2020

Investigation of a large SARS-CoV-2 outbreak among employees of a fruit grower in Okanogan County in Washington State between May and August 2020 found that cumulative incidence of SARS-CoV-2 infection was higher among employees living in the community than those living in congregate temporary housing (12% vs 4%). Cumulative incidence was highest among employees packing…

Next page