Result for
Topic: Clinical Characteristics and Health Care Setting
December 14, 2020
HIV Infection and COVID-19 Death: A Population-Based Cohort Analysis of UK Primary Care Data and Linked National Death Registrations within the OpenSAFELY Platform
A retrospective cohort study indicated that people with HIV in the UK (n = 27,480) had a higher risk of mortality from COVID-19 than those without HIV, after adjusting for age and sex (HR = 2.9). The risk remained high (HR = 2.6) after adjusting for index of multiple deprivation, smoking status, ethnicity, and obesity….
December 13, 2020
A Surge in Pediatric Coronavirus Disease 2019 Cases: The Experience of Texas Children’s Hospital from March to June 2020
A retrospective study of all children presenting to the Texas Children’s Hospital system who were tested for SARS-CoV-2 (16,554 unique patients), found that 1,215 (7%) patients tested positive, among whom 66% were Hispanic (representing 42% of the total number tested). Most children with detection of SARS-CoV-2 had uncomplicated illness courses, but 8% of children were…
December 11, 2020
Risk Factors Associated With In-Hospital Mortality in a US National Sample of Patients With COVID-19
A large cohort study (n=64,781) of patients with COVID-19 treated in 592 US hospitals during April and May 2020 found that the in-hospital mortality rate was 20.3%. Use of statin medications, angiotensin-converting enzyme inhibitors, and calcium channel blockers were associated with decreased odds of mortality. The combination use of hydroxychloroquine and azithromycin was associated with…
Analyses of Risk, Racial Disparity, and Outcomes Among US Patients With Cancer and COVID-19 Infection
A case-control analysis of electronic medical records from 73.4 million unique patients found that patients with a recent diagnosis of cancer were at significantly increased risk for COVID-19 infection and its adverse outcomes, especially among African Americans. Wang et al. (Dec 10, 2020). Analyses of Risk, Racial Disparity, and Outcomes Among US Patients With Cancer…
December 10, 2020
Severity of COVID-19 in Children with Cancer: Report from the United Kingdom Paediatric Coronavirus Cancer Monitoring Project
A retrospective and prospective observational study of all children in the UK under 16 diagnosed with cancer suggests that children with cancer do not appear to be at increased risk of severe SARS-CoV-2 infection compared to the general pediatric population. 54 cases were identified between March-July 2020 (3% estimated cumulative incidence); 5 (28%) were asymptomatic,…
December 8, 2020
Risk Factors for Severe COVID-19 in Middle-Aged Patients without Comorbidities: A Multicentre Retrospective Study
A multicenter retrospective study focusing on middle-aged (40-59 years) patients (n=119) without comorbidities who were hospitalized with COVID-19 found that 18 of 119 (15%) required mechanical ventilation and 5 of 119 (4%) died. The most common complications were acute respiratory distress syndrome (22%), acute liver injury (13%), and septic shock (4%). Wang et al. (Dec…
SARS-Coronavirus-2 Cases in Healthcare Workers May Not Regularly Originate from Patient Care: Lessons from a University Hospital on the Underestimated Risk of Healthcare Worker to Healthcare Worker Transmission
Investigation of 4 healthcare-associated SARS-CoV-2 outbreaks at a hospital in Germany resulting in 24 infected people suggests healthcare worker (HCW)-to-HCW transmission as the primary mechanism of spread rather than patient-to-HCW transmission. Further investigation showed multiple unprotected contacts between infected HCWs, and no further outbreaks were reported after implementation of contact tracing, testing, physical distancing and…
Three-Month Follow-Up Study of Survivors of Coronavirus Disease 2019 after Discharge
In a follow-up study of 76 COVID-19 survivors, most participants reported symptoms including fever, sputum production, fatigue, diarrhea, and chest tightness on exertion three months after hospital discharge. Pulmonary high-resolution CT was normal for 82% of participants, though 42% had mild pulmonary function abnormalities. 13% of participants were seronegative for IgG and 72% were seronegative…
Changes in Preterm Birth Phenotypes and Stillbirth at 2 Philadelphia Hospitals During the SARS-CoV-2 Pandemic, March-June 2020
A retrospective study at 2 Philadelphia hospitals did not detect significant changes between pre-pandemic and pandemic rates of adverse birth outcome. The adjusted difference between pre-pandemic and pandemic preterm births and stillbirths were -0.8% and -0.03 per 1,000 births, respectively. Spontaneous preterm birth among non-Hispanic white patients declined during the pandemic (4.5% vs 2.9%), but…
December 7, 2020
Clinical Status and Lung Function 10 Weeks after Severe SARS-CoV-2 Infection
54% of 220 patients who recovered from COVID-19 had abnormal lung function 10 weeks after diagnosis in a study using chest CT, pulmonary function testing, and COVID-19 symptoms in Belgium. Restrictive pulmonary impairment was the most common type of lung function impairment observed (38%) and was associated with longer hospital stay (8 vs 6 days),…
Previous page Next page