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Topic: Clinical Characteristics and Health Care Setting
September 22, 2020
SARS-CoV-2 Seroprevalence among Healthcare, First Response, and Public Safety Personnel, Detroit Metropolitan Area, Michigan, USA, May–June 2020
SARS-CoV-2 antibody testing of healthcare workers, first responders, and public safety personnel in EMS agencies and hospitals in Detroit (May-June 2020) indicated that 7% of participants had SARS-CoV-2 antibodies. Seropositivity was associated with exposure to SARS-CoV-2–positive household members (aOR=6.18) and working within 15 km of Detroit (aOR=5.60). Nurse assistants (aOR=1.88) and nurses (aOR=1.52) had higher…
September 21, 2020
Nonfatal Opioid Overdoses at an Urban Emergency Department During the COVID-19 Pandemic
In an emergency department in Richmond, Virginia, the total number of nonfatal opioid overdose visits between March-June 2020 was 227, a 2.2-fold increase compared to the same period in 2019 (n=102), with a higher proportion of patients who were Black (80% vs. 63%). Ochalek et al. (Sept 18, 2020). Nonfatal Opioid Overdoses at an Urban…
September 18, 2020
Recovered COVID-19 Patients with Recurrent Viral RNA Exhibit Lower Levels of Anti-RBD Antibodies
Patients who recovered from COVID-19 (n=47) and had a recurrent positive SARS-CoV-2 RNA test had significantly lower levels of anti-receptor binding domain (RBD) IgG antibodies than persistently RNA-negative patients (p=0.013). The authors conclude that this suggests that anti-RBD IgG levels could predict recovered patients who are at risk of viral rebound. Liu et al. (Sept…
Association Between CMS Quality Ratings and COVID-19 Outbreaks in Nursing Homes — West Virginia, March 17–June 11, 2020
Compared to West Virginia nursing homes receiving a 1-star (lowest quality) rating from the Centers for Medicare and Medicaid Services, 2- to 3- star-rated nursing homes had an 87% lower odds of a COVID-19 outbreak and 4- to 5- star-rated nursing homes had a 94% lower odds. Bui et al. (Sept 18, 2020). Association Between…
September 17, 2020
Preventing COVID-19 Outbreaks in Long-Term Care Facilities Through Preemptive Testing of Residents and Staff Members — Fulton County, Georgia, March–May 2020
There was a considerably higher proportion of positive SARS-CoV-2 test results among residents and staff in long-term care facilities when testing was conducted in response to an initial confirmed case of COVID-19 compared to preventive testing done before cases were detected. In Fulton County, Georgia, testing in response to an initial case in long-term care…
Serial Testing for SARS-CoV-2 and Virus Whole Genome Sequencing Inform Infection Risk at Two Skilled Nursing Facilities with COVID-19 Outbreaks — Minnesota, April–June 2020
During April–June 2020, serial facility-wide testing at two Minnesota skilled nursing facilities (SNFs) identified COVID-19 cases among 64% of residents (N=259) and 33% of health care personnel (N=341). Genetic sequencing found facility-specific clustering of viral genomes from healthcare professionals’ and residents’ specimens, suggesting intra-facility transmission. Taylor et al. (Sept 18, 2020). Serial Testing for SARS-CoV-2…
The COVID-19 Pandemic’s Impact on Critical Care Resources and Providers: A Global Survey
Female gender, being a nurse, reporting a shortage of ICU nurses and powered air-purifying respirators, as well as poor communication from supervisors were found to be positively associated with emotional distress or burnout among healthcare providers (n=2,700) for critically ill patients with COVID-19. These results were obtained from an electronic 41-question survey administered to health…
SARS-CoV-2 Infection Among Hospitalized Pregnant Women: Reasons for Admission and Pregnancy Characteristics — Eight U.S. Health Care Centers, March 1–May 30, 2020
Prevalence of pre-pregnancy obesity and gestational diabetes were higher among pregnant women hospitalized for COVID-19–related illness than among women admitted for obstetric reasons and later found to have COVID-19 (44% vs. 31%, and 26% vs. 8%, respectively). These findings were among 105 pregnant women hospitalized with SARS-CoV-2 in the US from March 1–May 30, 2020….
Mortality Rate and Predictors of Mortality in Hospitalized COVID-19 Patients with Diabetes
Older age (≥70 years) and a high serum lactate dehydrogenase (LDH) level significantly predicted mortality among hospitalized COVID-19 patients with diabetes in South Korea. Diabetes was present in 55 (17%) of 324 patients who were hospitalized with COVID-19 at two tertiary healthcare facilities. The mortality rate was much higher among patients with diabetes than among…
Characteristics and Maternal and Birth Outcomes of Hospitalized Pregnant Women with Laboratory-Confirmed COVID-19 — COVID-NET, 13 States, March 1–August 22, 2020
Among 598 pregnant women hospitalized with COVID-19 during March 1–August 22, 2020 in the US, 272 (45%) were symptomatic at admission, among whom 69 (25%) had severe illness during COVID-19-related hospitalizations, including ICU admissions (n=44), mechanical ventilation (n=23), and death (n=2). Ten women (7 symptomatic and 3 asymptomatic) experienced pregnancy losses. Delahoy et al. (Sept…
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