Alliance for Pandemic Preparedness

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Topic: Clinical Characteristics and Health Care Setting


March 23, 2020

Managing Cancer Care During the COVID-19 Pandemic: Agility and Collaboration Toward a Common Goal

This report highlights the unique challenges and circumstances of cancer treatment amidst the COVID-19 outbreak, and the importance of organizational structure, preparation, agility, and a shared vision for continuing to provide cancer treatment in these times of uncertainty and rapid change.  The report includes the Incident Command structure at the Seattle Cancer Care Alliance, which…


Rhabdomyolysis as Potential Late Complication Associated with COVID-19

While general muscle pain and fatigue are common symptoms of COVID-19, clinicians should consider the diagnosis of rhabdomyolysis when patients have focal muscle pain and fatigue. Rapid clinical recognition of rhabdomyolysis symptoms can be lifesaving. Jin & Tong (Mar 20, 2020). Rhabdomyolysis as Potential Late Complication Associated with COVID-19. Emerg Infect Dis. https://doi.org/10.3201/eid2607.200445 


Expert consensus for managing pregnant women and neonates born to mothers with suspected or confirmed novel coronavirus (COVID-19) infection

This report shares 10 key recommendations for management of COVID-19 during pregnancy.  Route of delivery and delivery timing should be individualized based on obstetrical indications and maternal-fetal status.  Chen et al. (Mar 20, 2020). Expert consensus for managing pregnant women and neonates born to mothers with suspected or confirmed novel coronavirus (COVID-19) infection. International Jour…


Telehealth for global emergencies: Implications for coronavirus disease 2019 (COVID-19)

Smith et al recognize the critical role of telehealth in emergency responses and share strategies for integrating telehealth into the general healthcare system. Some strategies include flexible funding arrangements, training and accrediting our health workforce, redesigning existing models of care and change management strategies.  Smith et al. (Mar 20, 2020). Telehealth for global emergencies: Implications…


First Pediatric Case of Coronavirus Disease 2019 in Korea

Park et al present the mild clinical course of the first pediatric case of COVID-19 in Korea and highlight the need to develop pediatric-specific guidelines on isolation and adequate PPE for caregivers.  Park et al. (Mar 23, 2020). First Pediatric Case of Coronavirus Disease 2019 in Korea. Jour Korean Med Sci. https://doi.org/10.3346/jkms.2020.35.e124 


March 20, 2020

COVID-19: What implications for sexual and reproductive health and rights globally?

The author discusses how SARS and MERS affected sexual and reproductive health and rights in different parts of the world, and argues the role principles of human rights should play in ensuring availability, accessibility and quality of medical services. Pregnant women with COVID-19 respiratory illness should be treated with priority because of the risk of…


COVID-19: Incidence, clinical characteristics and prognostic factors of patients with COVID-19: a systematic review and meta-analysis

This is the first evidence-based research exploring risk factors of prognosis in patients with COVID-19, which is helpful to identify early-stage patients with poor prognosis and adapt treatment.  Predictors of COVID-19 severity and mortality in this study were:  age (50+), sex (male) and presence of comorbidity such as hypertension, diabetes, cancer and respiratory disease. Additionally,…


Hundreds of severe pediatric COVID-19 infections in Wuhan prior to the lockdown

Du et al use influenza and COVID-19 surveillance data from hospitals in Wuhan to estimate cumulative pediatric COVID-19 hospitalizations prior to the Jan 23 lockdown. Their estimate of 1,105 cases far surpasses the 425 confirmed cases across all age groups, none of which were children under age 15.  This suggests there may be significantly more…


March 19, 2020

Pregnancy and Perinatal Outcomes of Women with Coronavirus Disease (COVID-19) Pneumonia: A Preliminary Analysis

Pregnancy and childbirth did not aggravate the course of symptoms or CT features of COVID-19 pneumonia in 15 pregnant women in this study, all of whom had mild symptoms and achieved good recovery from COVID-19. No SARS-CoV-2 infections were detected in the neonates. Liu et al. (Mar 7, 2020). Pregnancy and Perinatal Outcomes of Women…


The clinical and epidemiological features and hints of 82 confirmed COVID-19 pediatric cases aged 0-16 in Wuhan, China

Yu et al share the clinical and epidemiological features of 82 confirmed COVID-19 pediatric cases aged 0-16 years from a hospital in Wuhan. Most patients had a fever or cough at admission and mild symptoms. The hospital discharge rate was 73%, the mean hospital stay was 11.2 days and there were no fatalities.   Yu et…



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