Alliance for Pandemic Preparedness

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Topic: Clinical Characteristics and Health Care Setting


March 17, 2020

Radiology Department Preparedness for COVID-19: Radiology Scientific Expert Panel

In this report, the Radiology Editorial Board share policies developed by several healthcare systems describing their top priorities for COVID-19 preparedness in their environment.  Mossa-Basha et al. (Mar 16, 2020). Radiology Department Preparedness for COVID-19: Radiology Scientific Expert Panel. Radiology. https://doi.org/10.1148/radiol.2020200988


Clinical outcome of 55 asymptomatic cases at the time of hospital admission infected with SARS-Coronavirus-2 in Shenzhen, China

The study presents epidemiological and clinical characteristics of 55 asymptomatic carriers of SARS-CoV-2 in China. The authors found that asymptomatic infection was more common in middle aged people who had close contact with infected family members, and that a majority of cases developed mild or moderate symptoms. Wang et al. (Mar 17, 2020). Clinical outcome…


Risk Factors of Healthcare Workers with Corona Virus Disease 2019: A Retrospective Cohort Study in a Designated Hospital of Wuhan in China

This retrospective cohort study of 72 HCWs who developed acute respiratory symptoms while providing medical treatment at a tertiary hospital in Wuhan suggests that HCWs who worked in high-risk departments (departments with medical or surgical procedures that generate respiratory aerosols), long duty hours, and suboptimal hand hygiene after contact with patients had a higher risk…


A 55-Day-Old Female Infant infected with COVID 19: presenting with pneumonia, liver, and heart damage

This case study based on a 55-day old infant with COVID-19 in China reported that the infant had multiple organ damage and rapid disease changes. Identification, diagnosis, clinical course and disease progression, and treatment of this patient are described in detail.  Cui et al. (Mar 17, 2020). A 55-Day-Old Female Infant infected with COVID 19:…


March 16, 2020

Clinical Characteristics of 34 Children with Coronavirus Disease-2019 in the West of China: a Multiple-center Case Series

This retrospective, observational study of 34 children from 4 hospitals in China provides valuable insight into early diagnosis of COVID-19 in children and epidemic control policy making.  Compared to adults, initial symptoms in pediatric cases included higher incidences of fever, vomiting and diarrhea. The key radiological difference between children and adults was the near absence…


Relationship between the ABO Blood Group and the COVID-19 Susceptibility

By comparing blood group distribution in 2,200 COVID-19 cases from Wuhan hospitals and 3,700 controls from corresponding regions, Zhao et al found that ABO blood groups display different association risks for infection with SARS-CoV-2. Consistent with risk patterns of ABO blood groups for other coronavirus infections, group A was associated with an increased risk whereas…


Ocular manifestations and clinical characteristics of 534 cases of COVID-19 in China: A cross-sectional study

Findings from 534 COVID-19 patients from 2 hospitals in Wuhan suggest that conjunctivitis congestion was one of the COVID-19 related ocular symptoms, which may have clinical diagnostic significance.  Chen et al. (Mar 12, 2020). Ocular manifestations and clinical characteristics of 534 cases of COVID-19 in China: A cross-sectional study. Pre-print downloaded Mar 16 from https://doi.org/10.1101/2020.03.12.20034678


March 13, 2020

Retrospective Analysis of Clinical Features in 101 Death Cases with COVID-19

Based on a review of 101 COVID-19 fatalities from the Intensive Care Unit in a Wuhan hospital, the authors conclude that after lungs, the heart may be the next organ to experience damage.  Fan et al. (Mar 9, 2020). Retrospective Analysis of Clinical Features in 101 Death Cases with COVID-19. Pre-print downloaded on Mar 13…


The demand for inpatient and ICU beds for COVID-19 in the US: lessons from Chinese cities

This article highlights that healthcare resources may be higher in some US cities that have a higher prevalence of vulnerable populations.   Li et al. (Mar 9, 2020). The demand for inpatient and ICU beds for COVID-19 in the US: lessons from Chinese cities. Pre-print downloaded Mar 14 from https://doi.org/10.1101/2020.03.09.20033241 


Maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia: a case control study

Li et al conducted a case-control study that included 16 pregnant women with confirmed COVID-19 pneumonia and 18 suspected cases who were admitted in their third trimester. They did not find any evidence to suggest that COVID-19 pneumonia causes severe maternal and neonatal complications among these women who had vaginal or caesarean section. Li et…



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