Alliance for Pandemic Preparedness

Result for
Topic: Clinical Characteristics and Health Care Setting


March 13, 2020

Prolonged presence of SARS-CoV-2 in feces of pediatric patients during the convalescent phase

Based on 3 pediatric cases of COVID-19 that were reported in Qingdao, China, the authors conclude that SARS-CoV-2 may exist in the gastrointestinal tract for a longer time than the respiratory system. Viral RNA remained detectable in stools of these 3 cases for 8-20 days after the nucleic acid tests turned out negative in the…


March 12, 2020

Preparing for a COVID-19 pandemic: a review of operating room outbreak response measures in a large tertiary hospital in Singapore

Wong et al describe potential outbreak response measures for tertiary level acute care hospitals preparing for COVID-19.  Wong et al. (Mar 4, 2020). Preparing for a COVID-19 pandemic: a review of operating room outbreak response measures in a large tertiary hospital in Singapore. Canadian Journal of Anesthesia. https://doi.org/10.1007/s12630-020-01620-9 


Detection of Covid-19 in Children in Early January 2020 in Wuhan, China

This retrospective analysis of 366 children hospitalized in Wuhan early in the COVID-19 outbreak found that the most frequent pathogen identified was influenza A. 6 patients tested positive for COVID-19, presenting with moderate-to-severe symptoms. The findings indicate the COVID-19 infections in children were occurring early in the epidemic.  Liu et al (Mar 12, 2020). Detection…


Coronavirus Disease 2019 (COVID-19): Protecting Hospitals From the Invisible

Klompas emphasizes the need for hospitals to have more aggressive policies on respiratory hygiene and bolstering restrictions on patients, visitors, and health care workers to prevent further spread of COVID-19. Klompas (Mar 11, 2020). Coronavirus Disease 2019 (COVID-19): Protecting Hospitals From the Invisible. Annals of Internal Medicine. Article available here


How Should U.S. Hospitals Prepare for Coronavirus Disease 2019 (COVID-19)?

The authors describe detailed strategies for hospitals to consider when developing their preparedness plans for COVID-19.  Chopra et al. (Mar 11, 2020). How Should U.S. Hospitals Prepare for Coronavirus Disease 2019 (COVID-19)? Annals of Internal Medicine. Article available here


2019 novel coronavirus patients’ clinical characteristics, discharge rate and fatality rate of meta-analysis

Li et al summarize clinical data from 10 studies to describe the clinical symptoms, laboratory test data, and epidemiological characteristics of about 2,000 COVID-19 patients. The results of the meta-analysis showed that men accounted for 60% of COVID-19 patients, which was higher than women, and the case fatality was 7%. Li et al. (Mar 12,…


March 11, 2020

Mortality of COVID-19 is Associated with Cellular Immune Function Compared to Immune Function in Chinese Han Population

Zeng et al compare clinical characteristics and cellular immune functions between 752 COVID-19 patients and 14,117 controls in China. These findings may be helpful to clinicians who manage COVID-19 infections. Zeng et al. (Mar 10, 2020). Mortality of COVID-19 is Associated with Cellular Immune Function Compared to Immune Function in Chinese Han Population.  Pre-print downloaded…


A retrospective study of the clinical characteristics of COVID-19 infection in 26 children

In alignment with prior research, Tang et al conclude that children with COVID-19 tend to present with milder symptoms and better prognosis than adults.  Tang et al. (Mar 10, 2020). A retrospective study of the clinical characteristics of COVID-19 infection in 26 children.  Pre-print downloaded Mar 11 from https://doi.org/10.1101/2020.03.08.20029710


Ascertainment rate of novel 1 coronavirus disease (COVID-19) in Japan

The authors reviewed epidemiologic data for COVID-19 cases in Japan. Severe cases are more likely to be reported however they still account for a minority of all cases that occur.  Omori et al. (Mar 10, 2020). Ascertainment rate of novel 1 coronavirus disease (COVID-19) in Japan.  Pre-print downloaded Mar 11 from https://doi.org/10.1101/2020.03.09.20033183


The epidemiological characteristics of 2019 novel coronavirus diseases (COVID-19) in Jingmen, Hubei, China

Gao et al explore the epidemiological and clinical characteristics of 213 COVID-19 patients in Jingmen Hospital, China.  Gao et al. (Mar 10, 2020). The epidemiological characteristics of 2019 novel coronavirus diseases (COVID-19) in Jingmen, Hubei, China.  Pre-print downloaded Mar 11 from https://doi.org/10.1101/2020.03.07.20031393



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