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Topic: Clinical Characteristics and Health Care Setting
March 11, 2020
Clinical Characteristics of 2019 Coronavirus Pneumonia (COVID-19): An Updated Systematic Review
Fang et al conducted a systematic review of clinical characteristics, radiology findings on chest CT scan and laboratory findings of 3,468 lab confirmed COVID-19 patients. This large patient-based systematic review provides useful information for physicians who manage COVID-19 patients. Fang et al. (Mar 10, 2020). Clinical Characteristics of 2019 Coronavirus Pneumonia (COVID-19): An Updated Systematic…
March 10, 2020
Emergency management of the prevention and control of novel Coronavirus pneumonia in specialized branches of hospital
Ma et al discuss emergency management and prevention and control of COVID-19 in a hospital setting. They discuss changes in general, enforced ward and business management, leadership and hospital set up, and contingency plans. They report on personnel education and training, resource mobilization, three level prevention and control mechanisms, and environment and access management during…
Comparison of severe and non-severe COVID-19 pneumonia: review and meta-analysis
Ji et al reviewed literature to compare the difference between severe and non-severe COVID-19 pneumonia to identify common and symptoms associated with disease severity. Fever (89.2%), cough (67.2%), fatigue (43.6%) were common to severe and non-severe while polypnea/dyspnea, fever, and diarrhea were associated with severe disease. Ji et al. (Mar 9, 2020). Comparison of severe…
SARS-CoV-2 and COVID-19: facing the pandemic together as citizens and cardiovascular practitioners
Biondi-Zoccai et al describe the epidemiology, clinical signs, diagnosis, pharmaceutical and non-pharmaceutical interventions used, and clinical outcomes and associated complications of COVID-19 infection in Italy. The critical differential diagnoses for physicians is provided to proactively diagnose, risk-stratify, and manage patients with COVID-19 while not disregarding all other important cardiovascular conditions, which may well be worsened…
March 9, 2020
Managing neonates with respiratory failure due to SARS-CoV-2
De Luca provides a timely reflection and criticism of a suggested plan by Wang et al (Feb 7, 2020) to handle neonates with SARS-CoV-2 infections and outbreaks in neonatal intensive care units (NICUs). She proposes alternative plans to the limitations identified. De Luca (Mar 6, 2020). Managing neonates with respiratory failure due to SARS-CoV-2. Lancet…
Coronavirus in pregnancy and delivery: Rapid review and expert consensus
There are limited case series reporting impact of women affected by SARS-COV2. A few reports on SARS and MERS show a higher case fatality rate in pregnant women than COVID-19. Mullins et al, report on rapid review and expert consensus to guide management of women affected by COVID-19 during pregnancy. Mullins et al. (Mar 8,…
March 6, 2020
Gender differences in patients with COVID-19: Focus on severity and mortality
While men and women appear to have the same susceptibility to COVID-19, men appear to be at greater risk of higher severity and death, in line with prior reports and historical data for SARS-CoV. Jin et al. (Mar 5, 2020). Gender differences in patients with COVID-19: Focus on severity and mortality. Pre-print downloaded Mar 6…
Clinical characteristics of 36 non-survivors with COVID-19 in Wuhan, China
36 fatal COVID-19 cases are described. All cases progressed to acute respiratory distress syndrome (ARDS) with a median time from onset to ARDS of 11 days. Huang et al. (Mar 5, 2020). Clinical characteristics of 36 non-survivors with COVID-19 in Wuhan, China. Pre-print downloaded Mar 6 from https://doi.org/10.1101/2020.02.27.20029009
Clinical characteristics of 101 non-surviving hospitalized patients with COVID-19—A single center, retrospective study
In a review of 101 fatal COVID-19 cases, respiratory failure was noted in 100/101 cases while acute cardiac and kidney damage or failure were also identified as key factors in cause of death. Shi et al. (Mar 6, 2020). Clinical characteristics of 101 non-surviving hospitalized patients with COVID-19—A single center, retrospective study. Pre-print downloaded Mar…
Caution: The clinical characteristics of COVID-19 patients at admission are changing
A new study out of China compared symptoms at admission during early and late periods of the current COVID-19 outbreak. The authors report differences in symptom (e.g., systemic symptoms, such as fever, were more common in the early group but more severe in the later), suggesting that viral mutation may be responsible for changing symptom…
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