Alliance for Pandemic Preparedness

Result for
Topic: immunity


March 8, 2021

Comparison of IgG and Neutralizing Antibody Responses after One or Two Doses of COVID-19 MRNA Vaccine in Previously Infected and Uninfected Persons

[Pre-print, not peer-reviewed] A community-based, home-collected, longitudinal serosurvey of 290 participants before and after vaccination with either the Moderna or Pfizer/BioNTech vaccines found that a prior outpatient COVID-19 diagnosis was associated with strong anti-spike RBD IgG and in vitro neutralizing responses after one vaccine dose. Median IgG concentration and percent neutralization after one dose were…