Alliance for Pandemic Preparedness

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Topic: Transmission


September 23, 2020

Changing Age Distribution of the COVID-19 Pandemic — United States, May–August 2020

There was a shift in the age distribution of people affected by COVID-19 in the US between the period of January-May and June-August 2020, with a larger proportion of younger age groups affected in the later period. The authors conclude that this report provides preliminary evidence that younger adults contributed to community transmission of SARS-CoV-2…


Risk of Covid-19 Acquisition among Emergency Department Patients: A Retrospective Case Control Study. Infection Control & Hospital Epidemiology

Spending time in an emergency department (ED) at the same time as someone with COVID-19 did not appear to increase the risk of acquiring SARS-CoV-2 infection. These findings are based on a case-control study across 39 EDs in the western US including 102 cases who tested positive for SARS-CoV-2 following an ED encounter unrelated to…


September 22, 2020

Whole-Genome Sequencing to Track SARS-CoV-2 Transmission in Nosocomial Outbreaks

Whole virus genome viral sequencing of hospital-acquired cases of COVID-19 (March to April) in a tertiary referral center in Ireland indicated that the majority of the hospital-acquired cases occurred in patients highly dependent on nursing care. The authors conclude that this suggests that the likely route of transmission was by close contact or droplet, rather…


September 21, 2020

Viable SARS-CoV-2 in the Air of a Hospital Room with COVID-19 Patients

Lednicky et al. reported the detection of viable SARS-CoV-2 in air samples collected 2 to 4.8 m away from 2 hospitalized patients with COVID-19. The genome sequence of the SARS-CoV-2 strain isolated from air samplers was identical to that isolated from the newly admitted patient. The authors conclude that aerosols generated by patients with respiratory manifestations…


Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 During Long Flight

Following a 10-hour flight from London, UK to Hanoi, Vietnam on March 2, 2020, 16 of 217 passengers (7%) were found to be positive for SARS-CoV-2 after contact tracing, of whom 12 (75%) were seated in business class along with the only symptomatic person (attack rate 62%). Seating proximity was strongly associated with increased infection…


In-Flight Transmission of Severe Acute Respiratory Syndrome Coronavirus 2

Four individuals with SARS-CoV-2 infection had traveled on the same flight from Boston to Hong Kong on March 9, 2020. An epidemiologic investigation revealed that all four had identical virus genetic sequences belonging to a clade not previously identified in Hong Kong. The authors conclude that viral transmission likely occurred during the flight shared by…


A COVID-19 Nursing Home Transmission Study Sequence and Metadata from Weekly Testing in an Extensive Nursing Home Outbreak

[Pre-print, not peer reviewed] Residents with symptomatic and pre-symptomatic/unrecognized SARS-COV-2 infection in a Dutch nursing home outbreak had similar levels of viral shedding. Weekly facility-wide testing at the nursing home that began after admission of a resident who was recently hospitalized identified an additional positive residents (29 symptomatic, 38 pre-symptomatic, 7 asymptomatic), resulting in a…


Droplets and Aerosols Generated by Singing and the Risk of COVID-19 for Choirs

Image-based analysis showed that droplets expelled during singing followed the ambient airflow pattern and did not appear to settle down rapidly without adequate ventilation,pointing to aerosol generation during singing. The number of droplets expelled varied between individuals and parameters including loudness, notes, consonants, and duration of each note sung. Bahl et al. (Sept 18, 2020)….


September 18, 2020

SARS-CoV-2 in Quarantined Domestic Cats from COVID-19 Households or Close Contacts, Hong Kong, China

Six (12%) out of 50 healthy cats from COVID-19 households or close contacts in Hong Kong tested positive for SARS-CoV-2 using respiratory and fecal samples, suggesting human-to-feline transmission. Virus genomes sequenced from 1 cat and its owner were identical. Barrs et al. (Sept 18, 2020). SARS-CoV-2 in Quarantined Domestic Cats from COVID-19 Households or Close…


Clustering and Superspreading Potential of SARS-CoV-2 Infections in Hong Kong

Contact tracing data (n=1,038) was used to identify 4 to 7 superspreading events across 51 SARS-CoV-2 clusters in Hong Kong between January and April 2020. An estimated 19% of cases seeded 80% of all local transmission. While transmissions between household contacts were observed most frequently, transmissions that occurred in social settings were associated with more…



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