Result for
Topic: Transmission
March 31, 2020
Characteristics of Ocular Findings of Patients with Coronavirus Disease 2109 in Hubei Province, China.
Based on this study of ocular abnormalities in 38 COVID-19 patients in China, the authors suggest that while the prevalence of SARS-CoV-2 in tears is low, it may be possible to transmit through the eyes. Wu et al. (Mar 31, 2020). Characteristics of Ocular Findings of Patients with Coronavirus Disease 2109 in Hubei Province, China….
March 30, 2020
Children are unlikely to have been the primary source of household SARS-CoV-2 infections
Zhu et al investigated concerns that children could be an important source of SARS-CoV-2 in household transmission clusters. The observational study analyzed literature published on the clinical features of SARS-CoV-2 in children and household transmission clusters of SARS-CoV-2 in China, Singapore, South Korea, Japan, and Iran. Only 9.7% of clusters were identified as having a…
March 27, 2020
Antibodies in Infants Born to Mothers With COVID-19 Pneumonia
A study reviewed outcomes of six neonates, all delivered via C-section to COVID-19-positive mothers. All tested negative for SARS-CoV-2 and had generally favorable outcomes, however had elevated antibody and cytokine levels, indicating potential in-utero infection. A larger study of 33 neonates born to mothers with COVID-19 found that clinical symptoms were mild, outcomes were favorable,…
March 25, 2020
Internationally lost COVID-19 cases
The authors analyze available COVID-19 case data against countries’ Healthcare Access and Quality Index (HAQ), determining significantly less reporting of cases in countries with a lower HAQ. Findings suggest that countries with lower HAQs may either underreport or be unable to detect COVID-19 cases, which may sabotage efforts to contain the virus. Lau et al….
Epidemiological parameters of coronavirus disease 2019: a pooled analysis of publicly reported individual data of 1155 cases from seven countries.
This study obtained robust estimates of epidemiological parameters from 1,155 cases in China, Japan, Singapore, South Korea, Vietnam, Germany, and Malaysia. Findings support current quarantine practice, but also suggest that longer monitoring periods might be needed for selected groups due to consistent evidence of pre-symptomatic transmission. Ma et al. (March 24, 2020). Epidemiological parameters of…
Don’t overlook digestive symptoms in patients with 2019 novel coronavirus disease (COVID-19)
The study reviews findings from 183 hospitalized COVID-19 patients in Wuhan who presented only with gastrointestinal symptoms at admission – suggesting these patients could be likely overlooked. These findings suggest that the digestive system, along with the respiratory tract, may be a potential route for SARS-CoV-2 infection. Luo et al. (March 20, 2020). Don’t overlook…
COVID-19 Disease With Positive Fecal and Negative Pharyngeal and Sputum Viral Tests
A COVID-19 case screened positive for SARS-CoV-2 in a fecal specimen while testing negative on multiple pharyngeal and sputum samples. This indicates that the virus can proliferate in the digestive tract and potentially undergo fecal-oral transmission. Chen et al. (March 20, 2020). COVID-19 Disease With Positive Fecal and Negative Pharyngeal and Sputum Viral Tests. Am…
March 24, 2020
A Covid-19 Transmission within a family cluster by presymptomatic infections in China
The authors report a COVID-19 family cluster in China caused by a pre-symptomatic case. In line with current knowledge, these findings may indicate that COVID-19 is transmittable during the incubation period, and children are less susceptible and fare better when they have contacted the virus. Qian et al. (Mar 23, 2020). A Covid-19 Transmission within…
The first infant case of COVID-19 acquired from a secondary transmission in Vietnam
Le et al report about the first known case of secondary transmission of COVID-19 in an infant in Vietnam. Le et al. (Mar 23, 2020). The first infant case of COVID-19 acquired from a secondary transmission in Vietnam. Lancet Child & Adolesc Health. https://doi.org/10.1016/S2352-4642(20)30091-2
SARS-CoV-2: virus dynamics and host response
A cohort study analyzing the viral load and antibody profiles of 23 hospitalized patients with COVID-19 presents important findings: (1) the high viral load during the early phase of illness suggests that patients could be most infectious during this period, (2) the potential for antiviral resistance of SARS-CoV-2, (3) high viral loads in elderly patients…
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