Result for
Topic: Transmission
March 12, 2020
First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA
This article describes the epidemiologic investigation and contact tracing that was conducted on this first person-to-person transmission in the U.S. that occurred between two people with prolonged, unprotected exposure while the index patient (travel-associated case) was symptomatic. The authors note that despite actively monitoring almost 350 contacts and the 75 contacts who further developed COVID-19…
March 11, 2020
Estimation of incubation period distribution of COVID-19 using disease onset forward time: a novel cross-sectional and forward follow-up study
Qin et al conducted a longitudinal follow-up study of 1,211 asymptomatic individuals, who had travelled previously from Wuhan, until their symptoms developed. Findings suggest that about 10% of patients with COVID-19 may not develop symptoms until 14 days after infection. Further study of individuals with long incubation periods is warranted. Qin et al. (Mar 10,…
Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records
Chen et al retrospectively reviewed clinical and lab results for nine pregnant women with laboratory-confirmed COVID-19 pneumonia, for the presence of SARS-CoV-2 in amniotic fluid, cord blood, and neonatal throat swab samples. All the samples tested negative. Though limited in size, these findings reiterate findings from other recent studies suggesting that there is currently no…
Aerosol and surface stability of HCoV-19 (SARS-CoV-2) compared to SARS-CoV-1
There is new evidence indicating plausible fomite and aerosol transmission of COVID-19. Doremalen et al report that the stability of SARS-CoV-2 in the environment is similar to SARS-CoV-1. The agent can be detected in the aerosols up to 3 hours post aerosolization, up to 2 hours on copper, 24 hours on cardboard and up to…
March 10, 2020
A confirmed asymptomatic carrier of SARS-CoV-2
Luo et al report evidence of asymptomatic transmission of COVID-19. They discuss challenges in identifying asymptomatic carriers and patients during their asymptomatic phase and advocate for new preventive strategies to include this epidemiological evidence. Luo et al. (Mar 9, 2020). A confirmed asymptomatic carrier of SARS-CoV-2. Pre-print downloaded Mar 10 from https://doi.org/ 10.1097/CM9.0000000000000798
The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application
Lauer et al report that the median incubation period for COVID-19 is 5 days and 97.5% of those who develop symptoms will do so within 11.5 days (CI, 8.2 to 15.6 days) of infection. This means that, 101 out of every 10,000 cases will develop symptoms after monitoring or quarantine. The public health implications of…
March 9, 2020
The effect of human mobility and control measures on the COVID-19 epidemic in China
Kraemer and team used real-time human mobility data from Wuhan and detailed case data including travel history to predict the spread and growth rate of epidemics in China. They state that the spread of COVID-19 in China was driven by human mobility out of Wuhan early on and mitigated substantially by drastic control measures implemented…
Preliminary epidemiological analysis on children and adolescents with novel coronavirus disease 2019 outside Hubei Province, China: an observational study utilizing crowdsourced data
Henry et al used crowdsourced data to perform a preliminary epidemiologic analysis of pediatric patients with COVID-19. They reported higher incidence in males (52.4%) than females (32.9%). They present a descriptive analysis of pediatric cases, presenting symptom onset, time to medical care and clinical symptoms, ages most affected, and percentage noted to have infected a…
Estimating the burden of United States workers exposed to infection or disease: a key factor in containing risk of COVID-19 infection
Baker et al used data from Bureau of Labor Statistics to estimate the burden of US workers exposed to infection and disease in the workplace. They report that up to 10% (14.4 M) and 18% (26.7M) of Americans are employed in occupations where exposure to disease or infection occurs at least once per week and…
Evaluation of the incidence of COVID-19 and of the efficacy of contention measures in Spain: a data-driven approach
Much still remains unknown about the natural history of the disease. There is need to get insights into mobility-mediated transmission dynamics and it potential use in the containment of the epidemic. Aleta and Moreno using data-driven modelling, studied limiting mobility as containment strategies that could be implemented to stop large-scale spreading of the disease. Aleta…
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