Alliance for Pandemic Preparedness

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Topic: Transmission


March 18, 2021

Transmission Dynamics and Timing of Key Events for SARS-CoV-2 Infection in Healthcare Workers

In a retrospective study of healthcare workers (HCWs) in Turkey with SARS-CoV-2 infection (n=149), 98% of symptomatic HCWs had developed symptoms within 14 days of their index case developing symptoms. Among 39 HCW infector-infectee pairs, the median serial interval (time between symptom onset in the pair) was 4 days (IQR: 2-6). The authors suggest that…


March 17, 2021

Spread of a Variant SARS-CoV-2 in Long-Term Care Facilities in England

The proportion of SARS-CoV-2-positive samples that had an S gene target failure (suggestive of the B.1.1.7 strain) rose dramatically in late 2020 in the UK. The number and proportion of samples with S gene target failure increased from 12% to 60% between November 16 and December 13. By December 7, in South East England 57%…


SARS-CoV-2 Epidemiology on a Public University Campus in Washington State

[Pre-print, not peer-reviewed] A SARS-CoV-2 testing program at the University of Washington found that SARS-CoV-2 spread through school-based outbreaks without evidence of spread to the surrounding community. The testing program, which prioritized individuals with symptoms and high-risk exposure, identified 236 cases out of 16,476 tests conducted in the fall of 2020. Affiliation with a university…


SARS-CoV-2 Infection and Transmission in Primary Schools in England in June-December, 2020 (SKIDs): An Active, Prospective Surveillance Study

Results from the COVID-19 surveillance in School KIDSs (sKIDs) study of primary school children in England indicated that SARS-CoV-2 infection rates in primary schools were low following partial and full reopening. During the summer half-term (that began in June 2020), weekly infection rates were 4.1 per 100,000 students and 12.5 per 100,000 staff. Seropositivity for…


March 15, 2021

A Follow-up Study Shows That Recovered Patients with Re-Positive PCR Test in Wuhan May Not Be Infectious

A follow-up study analyzing data from 20,280 COVID-19 patients from multiple centers in Wuhan, China who received a positive PCR result between December 2019 and August 2020 found that 2,466 (12.2%) patients tested positive again (2,238 of were asymptomatic) after being discharged from the hospital. None of the 4,079 close contacts of patients who tested…


Limits of Lockdown Characterising Essential Contacts during Strict Physical Distancing

[Pre-print, not peer-reviewed] During the first lockdown in the UK, essential healthcare workers had 4.5 times as many contacts as non-essential workers (IRR = 4.4), while essential workers in other sectors like teaching and the police force had nearly three times as many contacts (IRR = 2.8), according to a study of participants in a…


Household SARS-CoV-2 Transmission and Children: A Network Prospective Study

A study of SARS-CoV-2 household transmission in Spain found that while viral transmission was common among household members (62.3%), among the 1,040 children under age 16 included in the study, more than 70% (756) of cases were acquired from an adult, whereas only 7.7% (80) were index cases. Almost half (47.2%) were asymptomatic, 10.8% had…


Transmission of SARS-CoV-2 Infection among Children in Summer Schools Applying Stringent Control Measures in Barcelona, Spain

A study of SARS-CoV-2 transmission among children and staff in summer schools in Spain during July 2020 found that the transmission rate under strict prevention measures was lower in school-like facilities than the general population. The authors compared transmission rates using a normalized effective reproduction number that accounted for the time spent in each setting….


March 12, 2021

Impact of the COVID-19 Vaccine on Asymptomatic Infection Among Patients Undergoing Pre-Procedural COVID-19 Molecular Screening

The risk of asymptomatic SARS-CoV-2 infection was significantly lower among patients who had received at least 1 dose of an mRNA COVID-19 vaccine compared to unvaccinated patients, based on a retrospective cohort study of asymptomatic adult patients (n=39,156) across multiple US states undergoing a pre-procedural SARS-CoV-2 molecular screening test. SARS-CoV-2 was detected in 3% of…


March 11, 2021

COVID-19 Infections among Students and Staff in New York City Public Schools

Testing of asymptomatic students and staff in New York public schools determined that the incidence of COVID-19 was lower among the school population (341.1 cases per 100,000) compared to the citywide population (528.9 cases per 100,000). Of 234,132 asymptomatic persons tested for SARS-CoV-2 infection in New York City public schools during October to December 2020,…



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