Alliance for Pandemic Preparedness

Result for
Topic: Transmission


March 29, 2021

SARS-CoV-2 Acquisition and Immune Pathogenesis Among School-Aged Learners in Four K-12 Schools

[Pre-print, not peer-reviewed] A study of SARS-CoV-2 infection in four schools (A-D) with either remote or onsite learning determined that infections in schools reflected regional infection rates rather than learning modality type (remote vs. onsite). School A (mostly low-income Hispanic students, remote instruction) had the highest frequency of infection (9/70, 12.9%) and IgG positivity (13/70,…


March 25, 2021

Emergence of the E484K Mutation in SARS-CoV-2 Lineage B.1.1.220 in Upstate New York

[Pre-print, not peer-reviewed] A novel SARS-CoV-2 variant (assigned name B.1.1.220) was detected by ongoing surveillance in samples collected in early February in four patients in upstate New York. B.1.1.220 was characterized with the E484K substitution in the spike protein, also present in the B.1.351 variant that was first described in South Africa and the P.1…


March 23, 2021

COVID-19 Cases Among Employees of U.S. Federal and State Prisons

The prevalence of COVID-19 infection among prison staff was estimated to be 3.2 times higher than the general U.S. population during the period of March 31, 2020 to November 4, 2020, according to an analysis of publicly available reports from the Bureau of Prisons. In 89% of jurisdictions, case burden among prison staff was greater…


March 19, 2021

Shelter Characteristics, Infection Prevention Practices, and Universal Testing for SARS-CoV-2 at Homeless Shelters in 7 US Urban Areas

Findings from SARS-CoV-2 testing offered to clients and staff at 63 homeless shelters, irrespective of symptoms, found lower prevalence of infection at shelters that implemented head-to-toe sleeping and that excluded symptomatic staff from working. Shelters with medical services available were less likely to have very high infection prevalence (defined as >10%). Self, J et al….


Pilot Investigation of SARS-CoV-2 Secondary Transmission in Kindergarten Through Grade 12 Schools Implementing Mitigation Strategies — St. Louis County and City of Springfield, Missouri, December 2020

School-based SARS-CoV-2 secondary transmission occurred in 2% of 102 close contacts identified in investigations of cases that occurred in K-12 schools (n=22) in Springfield and St. Louis County, Missouri. All schools offered in person-learning, with 21,342 (70%) students attending in-person at least part-time. While schools in both counties implemented COVID-19 mitigation strategies, schools in Springfield…


Low SARS-CoV-2 Transmission in Elementary Schools — Salt Lake County, Utah, December 3, 2020–January 31, 2021

Despite high community incidence and an inability to space classroom seats at least 6 feet apart, there was low SARS-CoV-2 transmission and no school-related outbreaks in 20 Salt Lake County elementary schools. Schools documented high mask adherence among students and also implemented multiple strategies to limit transmission. The authors suggest that these findings add to…


COVID-19 in Primary and Secondary School Settings During the First Semester of School Reopening — Florida, August–December 2020

COVID-19 school-related incidence among Florida students was low (August-December 2020), were most schools resumed in-person instruction sometime during August 2020, and was correlated with community incidence and was highest in smaller counties, districts without mask requirements, and those that reopened earliest after closure in March 2020. A total of 63,654 total cases of COVID-19 were…


March 18, 2021

Minimal SARS-CoV-2 Transmission After Implementation of a Comprehensive Mitigation Strategy at a School — New Jersey, August 20–November 27, 2020

A New Jersey private boarding school with high adherence to COVID-19 mitigation protocols reported 17 positive PCR tests among faculty and staff (0.18% of total) and 8 positive tests among students (0.06% of total) during August to November 2020. Case investigations found likely off-campus sources for all but 2 of the positive cases (both students),…


Notes from the Field: SARS-CoV-2 Transmission Associated with High School Football Team Members — Florida, September–October 2020

In an outbreak investigation by the Florida Department of Health, an index case of COVID-19 in a high school football player was linked to an additional 18 confirmed cases (12 players, 2 coaches, and 2 non-player classroom contacts). Because of potential close contact between infected team members and classmates, 267 students at the football team’s…


Estimating the Increased Transmissibility of the B.1.1.7 Strain over Previously Circulating Strains in England Using Fractions of GISAID Sequences and the Distribution of Serial Intervals.

[Pre-print, not peer-reviewed] The SARS-CoV-2 B.1.1.7 strain is suggested to be 40% more transmissible than previously circulating strains, according to a model-based analysis using the time course of the proportion of SARS-CoV-2 infections with the B.1.1.7 variant applied to SARS-CoV-2 genome sequence data and the distribution of serial intervals in England. For mitigation, the authors…



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