Digital Reference Object
Updated: 21 June 2016

DRO Descriptions




Amyloid DRO Volumes (30 volumes) (BETA)

The PET/CT Digital Reference Objects (DROs) are synthetically generated DICOM image files of known voxel values for positron emission tomography (PET) and x-ray computed tomography (CT).
The University of Washington Imaging Research Laboratory currently offers five PET and PET/CT Digital Reference Objects:

DRO for SUV Computation

The DRO for calculation of PET SUV values can be found here

DROe for SUVpeak, Fusion Alignment, and ROI Fidelity

The DROe for testing SUVpeak calculations, PET/CT fusion alignment, and ROI fidelity can be found here

DROmtv for Metabolic Tumor Volume Computation

The DROmtv for calculation of PET Metabolic Tumor Volume can be found here. A noisy version of the DROmtv is also available.

DRObrain for Differential Amyloid Uptake

The DROmtv for calculation of PET Metabolic Tumor Volume can be found here.

Hoffman Brain Phantom DRO

A digital version of the ubiquitous Hoffman Phantom can be found here.


The PET/CT DROs are supported by the Quantitative Imaging Biomarker Alliance (QIBA).

The primary goals and objectives of the PET/CT Digital Reference Objects are to support the QIBA FDG-PET 'Technical Validation' efforts for profile development by providing common reference standards that can be adopted and modified by PET/CT scanner and display station manufacturers.