A study in the journal Cell Metabolism showed that a reduction in glucose-dependent granule docking is associated with impaired insulin secretion among patients with type 2 diabetes. Researchers compared the beta cells of patients with and without diabetes and found that diabetes patients’ beta cells had a defect in the attachment of insulin vesicles to the cell membrane, which is attributed to a reduced number of proteins responsible for these attachments.
Diabetes (UK) (2/8)