Diabetes News You Can Use
Study: Clinical trial participants say sharing health data is beneficial
Eighty-one percent and more than 85% of 771 surveyed clinical trial participants reported that data sharing would benefit physicians and scientists, respectively, according to a study in The New England Journal of Medicine. Less than 10% of respondents reported being “very” concerned about the possible consequences of data sharing, while less than a third expressed being “very” or “somewhat” concerned about the potential risks, including the possibility of their information being hacked or used for poor-quality research.
Insulin levels stabilize after 7 years of annual declines, study finds
A study in Diabetes Care showed that insulin levels decline by nearly 50% every year for seven years in type 1 diabetes patients, but stabilize thereafter. UK researchers evaluated 1,549 type 1 diabetes patients and said the findings indicate patients will keep any remaining working beta-cells seven years after diagnosis, which could lead to new therapies.
Diabetes (UK) (6/8)
Dual-hormone system tied to reduced hypoglycemia in diabetes, study finds
ADA leads effort to demand insulin pricing transparency
Several stakeholders from the diabetes community, including the American Diabetes Association, asked legislators with the Senate Special Committee on Aging for help regarding transparency with the increasing prices of insulin. The ADA’s insulin access and affordability working group released a consensus statement, published in Diabetes Care, that identified the factors influencing insulin prices and highlighted the difference between the list price and “net” price of insulin, noting the lack of data that outlines the differences.
Study links antipsychotic drugs to gestational diabetes risk
Pregnant women who took the antipsychotics olanzapine or quetiapine were at higher risk of gestational diabetes than those who stopped treatment during pregnancy, according to a study published in The American Journal of Psychiatry and presented at the American Psychiatric Association’s annual meeting. Women who continued the drugs while pregnant had greater comorbidity and longer antipsychotic use.
Diabetes Research Center
Related News
Congratulations to this year’s funding awardees
Pilot and Feasibility Awardees
Mauricio Dorfman, Ph.D.
Research Assistant Professor
Department of Medicine
Oleg Zaslavsky, Ph.D., M.H.A., R.N.
Assistant Professor
Department of Biobehavioral Nursing
and Health Informatics
Dick and Julia McAbee Fellowship Awardee
Meghan F. Hogan, Ph.D.
(Mentor: Steven E. Kahn, M.B., Ch.B.)
Postdoctoral Research Fellow
Department of Medicine
Samuel and Althea Stroum Fellowship Awardee
Sam Entwisle
(Mentor: Judit Villen, Ph.D.)
Graduate Student
Department of Genome Sciences
Studies Show Increasing Prevalence of Type 1 and Type 2 Diabetes in Youth and Increased Risk of Diabetic Complications in Youth with Type 2 Diabetes
Catherine Pihoker and Santica Marcovina, two UW Diabetes Research Center affiliates, are authors on recent papers highlighting diabetes in youth. In the one study published in The New England Journal of Medicine on April 13, using data from the ongoing SEARCH for Diabetes in Youth study they and their colleagues showed that between 2002 and 2012 the adjusted relative incidence rates of type 1 and type 2 diabetes among US youth had increased annually 1.8% and 4.8%, respectively. The highest annual rate of increase for type 1 diabetes was among Hispanic youth and among Native American youth for type 2 diabetes. The second study also used data from SEARCH for Diabetes in Youth study and was published on February 28 in The Journal of the American Medical Association. In this study, it was found that in 1,746 youth with type 1 diabetes and 272 with type 2 diabetes who had been followed for an average of 7.9 years, both groups had diabetic complications. Those with type 2 diabetes had a greater risk of developing diabetic kidney disease, retinopathy and peripheral neuropathy than those with type 1 diabetes.
DRC Welcomes First Year Medical Students
Congratulations and welcome to the first year medical students that have been accepted into the prestigious NIDDK-funded Medical Student Summer Research Program in Diabetes and will be spending the summer at UW, performing diabetes-related research in the laboratories of DRC affiliates. The 2017 awardees are:
| Name | Medical School | UW Mentor |
| Jessica Chau | California Northstate University | Karin Bornfeldt |
| Ye Choi | The University of Texas Rio Grande Valley | Chris Hampe |
| Graham Dixon | East Carolina University | Rebecca Hull |
| Eddie Khav | Midwestern University | Jarrad Scarlett |
| Melinda Ma | University of California, Riverside School of Medicine | Ellen Schur |
| Niveda Shekar | Midwestern University | Mario Kratz |
| Nancy Shen | Midwestern University | Sakeneh Zraika |
| Anthony Therattil | Touro College and Univ System, New York Medical College | Greg Morton |
Neprilysin deficiency reduces DPP-4 activity and increases active GLP-1 in a mouse model of type 2 diabetes
Editor’s pick: The manuscript authored by Sakeneh Zraika, Joshua Willard and Breanne Barrow was featured in Diabetologia’s April issue as one of five selected by the Editor that merit special attention. The study shows for the first time that inhibition of the peptidase neprilysin reduces DPP-4 activity in high fat-fed mice, and is associated with improved glycemic status.
Markers of Islet Endothelial Dysfunction Occur in Male B6.BKS(D)-Leprdb/J Mice and May Contribute to Reduced Insulin Release
Upcoming Events
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The Diabates and Metabolism Seminar Series will resume in the Fall.
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