Diabetes News You Can Use
Excess weight, obesity affects more than 2 billion people worldwide
USA Today/The Associated Press (6/12), The New York Times (free-article access for SmartBrief readers) (6/12), HealthDay News (6/12)
News provided by DiabetesPro SmartBrief in conjunction with the American Diabetes Association.
Study examines racial differences in link between mean glucose, A1C levels
Healio (free registration) (6/12)
News provided by DiabetesPro SmartBrief in conjunction with the American Diabetes Association.
Study examines severe hypoglycemia with intensive treatment for type 1 diabetes
Researchers analyzed data from the Diabetes Control and Complications Trial and Epidemiology of Diabetes Interventions and Complications study that ran between 1983 and 1993 and found that type 1 diabetes patients in the intensive treatment group had three times as many severe hypoglycemic episodes as those in the non-intensive group. The findings in Diabetes Care revealed that more than 20 years after the trial ended, those in the non-intensive group experienced 0.41 episodes of severe hypoglycemia per year, compared with 0.37 among those in the formerly intensively controlled group.
Diabetes.co.uk (U.K.) (5/30)
News provided by DiabetesPro SmartBrief in conjunction with the American Diabetes Association.
Study ties long-term metformin use to reduced CAC in men
A longitudinal cohort study in Circulation found long-term use of metformin was associated with significantly lower severity and prevalence of coronary artery calcium in men, but not women, who initiated the drug for prediabetes. The findings were based on 2,776 participants in the Diabetes Prevention Program and its DPP Outcomes Study.
Medscape (free registration) (5/30)
News provided by DiabetesPro SmartBrief in conjunction with the American Diabetes Association.
Researchers ID 111 additional loci tied to type 2 diabetes
United Press International (5/8)
News provided by DiabetesPro SmartBrief in conjunction with the American Diabetes Association.
Diabetes Research Center
Related News
Studies Show Increasing Prevalence of Type 1 and Type 2 Diabetes in Youth and Increased Risk of Diabetic Complications in Youth with Type 2 Diabetes
Catherine Pihoker and Santica Marcovina, two UW Diabetes Research Center affiliates, are authors on recent papers highlighting diabetes in youth. In the one study published in The New England Journal of Medicine on April 13, using data from the ongoing SEARCH for Diabetes in Youth study they and their colleagues showed that between 2002 and 2012 the adjusted relative incidence rates of type 1 and type 2 diabetes among US youth had increased annually 1.8% and 4.8%, respectively. The highest annual rate of increase for type 1 diabetes was among Hispanic youth and among Native American youth for type 2 diabetes. The second study also used data from SEARCH for Diabetes in Youth study and was published on February 28 in The Journal of the American Medical Association. In this study, it was found that in 1,746 youth with type 1 diabetes and 272 with type 2 diabetes who had been followed for an average of 7.9 years, both groups had diabetic complications. Those with type 2 diabetes had a greater risk of developing diabetic kidney disease, retinopathy and peripheral neuropathy than those with type 1 diabetes.
DRC Welcomes First Year Medical Students
Congratulations and welcome to the first year medical students that have been accepted into the prestigious NIDDK-funded Medical Student Summer Research Program in Diabetes and will be spending the summer at UW, performing diabetes-related research in the laboratories of DRC affiliates. The 2017 awardees are:
| Name | Medical School | UW Mentor |
| Jessica Chau | California Northstate University | Karin Bornfeldt |
| Ye Choi | The University of Texas Rio Grande Valley | Chris Hampe |
| Graham Dixon | East Carolina University | Rebecca Hull |
| Eddie Khav | Midwestern University | Jarrad Scarlett |
| Melinda Ma | University of California, Riverside School of Medicine | Ellen Schur |
| Niveda Shekar | Midwestern University | Mario Kratz |
| Nancy Shen | Midwestern University | Sakeneh Zraika |
| Anthony Therattil | Touro College and Univ System, New York Medical College | Greg Morton |
Neprilysin deficiency reduces DPP-4 activity and increases active GLP-1 in a mouse model of type 2 diabetes
Editor’s pick: The manuscript authored by Sakeneh Zraika, Joshua Willard and Breanne Barrow was featured in Diabetologia’s April issue as one of five selected by the Editor that merit special attention. The study shows for the first time that inhibition of the peptidase neprilysin reduces DPP-4 activity in high fat-fed mice, and is associated with improved glycemic status.
2017 Short-Course on Quantitative Digital Pathology (QDP)
This course is designed and run by the Center’s Cellular and Molecular Imaging Core leadership. It is an intensive course focused on the principles and methods used in stereology and image analysis to obtain accurate non-biased data from tissue sections. This is a unique opportunity to interact with experts in the field of stereology and image analysis.
October 23-27, 2017
For additional information contact Charles W. Frevert, DVM, ScD (cfrevert@uw.edu) or Brian Johnson (brianj18@uw.edu).
Markers of Islet Endothelial Dysfunction Occur in Male B6.BKS(D)-Leprdb/J Mice and May Contribute to Reduced Insulin Release
Upcoming Events
The Diabates and Metabolism Seminar Series will resume in the Fall.Other Events
Pacific Northwest Diabetes Research Institute
David R. Beier, M.D., Ph.D. (Pacific Northwest Diabetes Research Institute)
07-11-2017 - 11:00 am
Pacific Northwest Diabetes Research Institute
720 Broadway
Seattle, WA 98122
TBD
Seattle Children's Hospital
Center for Developmental Biology and Regenerative Medicine, Director
Location: Renshaw Conference Room
Pacific Northwest Diabetes Research Institute
Gregory Carter, Ph.D. (Pacific Northwest Diabetes Research Institute)
08-15-2017 - 11:00 am
Pacific Northwest Diabetes Research Institute
720 Broadway
Seattle, WA 98122
Using Genetic Complexity to Understand Complex Disease
The Jackson Laboratory
Associate Professor
Location: Renshaw Conference Room
Cystic Fibrosis Research Seminar Series
Annual Retreat (Cystic Fibrosis Research Seminar Series)
09-27-2017 - 8:00 am
UW Center for Urban Horticulture
3501 NE 41st Street
Seattle, WA 98195
Location: UW Center for Urban Horticulture