Diabetes News You Can Use
More sleep may lower type 2 diabetes risk in youths
Nine- and 10-year-olds who got an additional hour of sleep during weekdays had a 2.9% reduction in insulin resistance, 0.24% lower fasting glucose and 0.19% lower body mass index, which are risk factors for type 2 diabetes, compared with those who got less sleep, UK researchers reported in Pediatrics. However, the findings didn’t show a link between sleep duration and HbA1C levels or cardiovascular risk.
The New York Times (free-article access for SmartBrief readers) (8/15), MedPage Today (free registration) (8/15)
News provided by DiabetesPro SmartBrief in conjunction with the American Diabetes Association.
Study finds 2-hour postload glucose effective in predicting CV events in CAD
Researchers found that two-hour postload glucose was a better predictor of cardiovascular events among patients with coronary artery disease but without previously known diabetes than A1C or fasting plasma glucose. The findings in Diabetes Care, based on 3,775 patients, revealed that an A1C between 5.7% and 6.5% and 2h-PG between 7.8 and 11.0 mmol/L were independent predictors of incident diabetes.
Endocrinology Advisor (7/20)
News provided by DiabetesPro SmartBrief in conjunction with the American Diabetes Association.
Researchers examine prevalence of DPN among youths with diabetes
Medscape (free registration) (7/21)
News provided by DiabetesPro SmartBrief in conjunction with the American Diabetes Association.
Study finds nearly half of Chinese adults suffer from prediabetes or diabetes
Medscape (free registration) (6/27)
News provided by DiabetesPro SmartBrief in conjunction with the American Diabetes Association.
Study ties gut microbiome changes to metabolic markers
Diabetes.co.uk (U.K.) (6/20)
News provided by DiabetesPro SmartBrief in conjunction with the American Diabetes Association.
Diabetes Research Center
Related News
ITHS TRANSLATIONAL PILOT AWARD WITH A SPECIAL EMPHASIS ON DIABETES
ITHS TRANSLATIONAL PILOT AWARD WITH A SPECIAL EMPHASIS ON DIABETES
2018-2019 RFA
In conjunction with the Diabetes Research Center at the University of Washington, the ITHS is offering a Translational Pilot Award with a Special Emphasis on Diabetes to support studies that address impactful research issues within the translational science spectrum, with the long-term goal of improving the health of patients with diabetes.
Examples might include pre-clinical work with animal models, clinical observational or implementation studies, or public health outcomes research related to diabetes and its complications.
Applications are due by September 1, 2017. Further details are available at https://www.iths.org/investigators/funding/tpa-diabetes/2018-2019-rfa/
Congratulations to this year’s funding awardees
Pilot and Feasibility Awardees
Mauricio Dorfman, Ph.D.
Research Assistant Professor
Department of Medicine
Oleg Zaslavsky, Ph.D., M.H.A., R.N.
Assistant Professor
Department of Biobehavioral Nursing
and Health Informatics
Dick and Julia McAbee Fellowship Awardee
Meghan F. Hogan, Ph.D.
(Mentor: Steven E. Kahn, M.B., Ch.B.)
Postdoctoral Research Fellow
Department of Medicine
Samuel and Althea Stroum Fellowship Awardee
Sam Entwisle
(Mentor: Judit Villen, Ph.D.)
Graduate Student
Department of Genome Sciences
Cystic Fibrosis Post-doctoral Fellowship and Pilot and Feasibility Study Call for Applications
The Cystic Fibrosis Research Center is pleased to announce two RFAs from the CF Research Development Program (RDP) – for Pilot and Feasibility Projects and for Post-Doctoral Research Fellowships. Up to five total applicants may be funded starting as early as October 1, 2017. Please see the attached RFA Announcements and Policy and Guidelines for further details.
New this cycle: we are requesting short letters of intent for Pilot and Feasibility Projects and Post-Doctoral Research Fellowships applications. The letters of intent will help us plan support from CF core facilities. In some cases we may also provide programmatic advice prior to receiving full applications.
Upcoming Due Dates
July 10th Letter of Intent for Pilot and Feasibility Projects
July 17th Letter of Intent for Post-doctoral Fellowship Projects
August 15th All applications due (institutional signatures not required)
Please feel free to contact Drs. Pradeep Singh, Bonnie Ramsey or Pete Greenberg if you have any questions about your application. Contact Donna Crist (donna.crist@seattlechildrens.org) for an application packet or with questions about the application process.
Download flyers:
RFA for RDP Pilots Spring 2017 flyer
CFF RDP Pilot Policy and Guidelines
RFA for RDP Fellows Spring 2017 flyer
CFF RDP Fellows Policy and Guidelines
Studies Show Increasing Prevalence of Type 1 and Type 2 Diabetes in Youth and Increased Risk of Diabetic Complications in Youth with Type 2 Diabetes
Catherine Pihoker and Santica Marcovina, two UW Diabetes Research Center affiliates, are authors on recent papers highlighting diabetes in youth. In the one study published in The New England Journal of Medicine on April 13, using data from the ongoing SEARCH for Diabetes in Youth study they and their colleagues showed that between 2002 and 2012 the adjusted relative incidence rates of type 1 and type 2 diabetes among US youth had increased annually 1.8% and 4.8%, respectively. The highest annual rate of increase for type 1 diabetes was among Hispanic youth and among Native American youth for type 2 diabetes. The second study also used data from SEARCH for Diabetes in Youth study and was published on February 28 in The Journal of the American Medical Association. In this study, it was found that in 1,746 youth with type 1 diabetes and 272 with type 2 diabetes who had been followed for an average of 7.9 years, both groups had diabetic complications. Those with type 2 diabetes had a greater risk of developing diabetic kidney disease, retinopathy and peripheral neuropathy than those with type 1 diabetes.
DRC Welcomes First Year Medical Students
Congratulations and welcome to the first year medical students that have been accepted into the prestigious NIDDK-funded Medical Student Summer Research Program in Diabetes and will be spending the summer at UW, performing diabetes-related research in the laboratories of DRC affiliates. The 2017 awardees are:
| Name | Medical School | UW Mentor |
| Jessica Chau | California Northstate University | Karin Bornfeldt |
| Ye Choi | The University of Texas Rio Grande Valley | Chris Hampe |
| Graham Dixon | East Carolina University | Rebecca Hull |
| Eddie Khav | Midwestern University | Jarrad Scarlett |
| Melinda Ma | University of California, Riverside School of Medicine | Ellen Schur |
| Niveda Shekar | Midwestern University | Mario Kratz |
| Nancy Shen | Midwestern University | Sakeneh Zraika |
| Anthony Therattil | Touro College and Univ System, New York Medical College | Greg Morton |
Neprilysin deficiency reduces DPP-4 activity and increases active GLP-1 in a mouse model of type 2 diabetes
Editor’s pick: The manuscript authored by Sakeneh Zraika, Joshua Willard and Breanne Barrow was featured in Diabetologia’s April issue as one of five selected by the Editor that merit special attention. The study shows for the first time that inhibition of the peptidase neprilysin reduces DPP-4 activity in high fat-fed mice, and is associated with improved glycemic status.
2017 Short-Course on Quantitative Digital Pathology (QDP)
This course is designed and run by the Center’s Cellular and Molecular Imaging Core leadership. It is an intensive course focused on the principles and methods used in stereology and image analysis to obtain accurate non-biased data from tissue sections. This is a unique opportunity to interact with experts in the field of stereology and image analysis.
October 23-27, 2017
For additional information contact Charles W. Frevert, DVM, ScD (cfrevert@uw.edu) or Brian Johnson (brianj18@uw.edu).
Markers of Islet Endothelial Dysfunction Occur in Male B6.BKS(D)-Leprdb/J Mice and May Contribute to Reduced Insulin Release
Upcoming Events
The Diabates and Metabolism Seminar Series will resume in the Fall.Other Events
Dept of Medicine Grand Rounds
Designs using Active Controls: Non-inferiority Trials (DoM Grand Rounds)
08-31-2017 - 8:00 am
UW Health Sciences Building
1959 NE Pacific St
Seattle, WA 98195
Thomas Fleming, PhD
Professor, Biostatistics & Statistics
University of Washington
Room Location: T-625
Dept of Medicine Grand Rounds
Addiction Medicine Matters (Dept of Medicine Grand Rounds)
09-07-2017 - 8:00 am
UW Health Sciences Building
1959 NE Pacific St
Seattle, WA 98195
Joseph O. Merrill, MD, MPH
Associate Professor
Department of Medicine, Division of General Internal Medicine
UW School of Medicine
Room Location: T-625
Dept of Medicine Grand Rounds
The Male Pill: Game Changer or Pipe Dream? (Dept of Medicine Grand Rounds)
09-14-2017 - 8:00 am
UW Health Sciences Building
1959 NE Pacific St
Seattle, WA 98195
Stephanie T. Page, MD, PhD
Professor and Head
Department of Medicine, Division of Metabolism, Endocrinology & Nutrition
UW School of Medicine
Room Location: T-625