Diabetes News You Can Use
FDA panel: Bivalent COVID-19 vaccines should become standard
An FDA advisory committee unanimously supported a recommendation to simplify the US COVID-19 vaccination program by phasing out vaccines that target only the original SARS-CoV-2 variant and shifting to use of the bivalent Omicron booster doses by Pfizer and Moderna for the entire vaccination series. Another proposal discussed but not voted on was adoption of a more streamlined COVID-19 vaccine dosing schedule for Americans based on age and health risks.
VA facilities’ SGLT2i prescribing varies by certain factors
Researchers the American Journal of Kidney Diseases found some variation in SGLT2i prescription among Veterans with chronic kidney, diabetes, and cardiac diseases, depending on race and sex and where patients received care in the VA system. Findings showed that 11.5% of the Veterans were given an SGLT2i prescription, 80% of patients taking the SGLT2i were white, 12.3% were Black or African-American, a comparable trend was noted between men and women, and there was a 58% variation in treatment among VA hospitals, with researchers noting that they did not find an explanation for the differences between facilities.
Full Story: Healio (free registration) (1/25)
Frailty risk higher in adults with abdominal, general obesity
A study found that adults with both abdominal and general obesity based on waist circumference and body mass index had a higher risk of becoming prefrail or frail than those with normal WC and BMI. The findings, published in the journal BMJ Open, looked at 2,169 men and 2,340 women study participants.
Full Story: HealthDay News (1/24)
Meta-analysis identifies genes linked to T2D risk
An international consortium of researchers identified specific genes that regulate insulin processing and glucose and thus might be linked to type 2 diabetes risk and related mechanisms of T2D development. The meta-analysis of genomewide association studies integrated analyses of proinsulin loci with complementary glycemic traits, gene expression in trait-relevant tissues and functional follow-up, providing “candidate genes for T2D and hypotheses on potential avenues of mechanism for known T2D loci,” the researchers wrote in the American Journal of Human Genetics.
Full Story: GenomeWeb Daily News (free registration) (1/23)
Cancer mortality risk increases in older patients with T2D
Researchers looked at data involving 137,000 patients with type 2 diabetes and found that individuals aged 75 and 85 had 1.2% and 1.6% increased average annual percentage changes related to cancer mortality, respectively. The study, published in Diabetologia, also revealed an annual cancer-related mortality rate drop of 1.4% and 0.2% in patients with T2D who are 55 and 65 years old, respectively.
Full Story: MedPage Today (free registration) (1/24)
Study links diabetic retinopathy and foot ulcers, amputation
Diabetic retinopathy is independently associated with a higher risk of developing diabetic foot ulcers and amputation among people with type 2 diabetes who are hospitalized, according to research published in the journal Diabetes/Metabolism Research and Reviews. Researchers evaluated over 500 people who had diabetes with a follow-up period of 52 weeks.
Full Story: Medical Dialogues (1/18)
FDA approves bexagliflozin for type 2 diabetes
TheracosBio’s oral sodium-glucose cotransporter 2 inhibitor Brenzavvy, or bexagliflozin, has gained FDA approval as an adjunct to exercise and diet for improving glycemic control in type 2 diabetes patients. The approval was supported by data from 23 clinical trials with more than 5,000 participants.
Full Story: eMPR (1/23)
American Diabetes Association’s Standards of Care in Diabetes–2023
Learn about the important updates to this year’s Standards of Care in Diabetes–2023 from the American Diabetes Association and how those changes impact clinical care, especially as they relate to type 2 diabetes and cardiovascular disease. Join us on Feb. 8 at 2 p.m. ET for our webinar, American Diabetes Association’s Standards of Care in Diabetes–2023. Register now.
Poll: 52% of Americans rate US health care as fair, poor
A new Gallup poll found that 52% of Americans believe the quality of US health care is “only fair” or “poor,” marking the first time in the survey’s two decades that the share of adults giving “good” or “excellent” ratings to the nation’s health care dropped below half to 48%. Almost 50% of respondents said there are major problems in US health care, while 20% believe the nation’s health care is in a “state of crisis,” the largest percentage in about a decade.
Study: Less dietary salt may help lower CVD, stroke risks
Replacing some dietary salt with a potassium-enriched salt substitute was associated with reduced risk of stroke or cardiovascular events, according to research published in the journal Hypertension. “Interventions that reduce dietary sodium, increase dietary potassium, or both have significant potential for blood pressure lowering and cardiovascular protection,” researchers wrote.
Full Story: Healio (free registration)/Cardiology Today (1/19)