Andrew Hoofnagle


UW Health Sciences Center

Laboratory Medicine


Research Interest: Clinical Trials and Large-Scale Epidemiologic Studies, Complications of Diabetes

DRC Publications

Nelson, JE; Roth, CL; Wilson, LA; Yates, KP; Aouizerat, B; Morgan-Stevenson, V; Whalen, E; Hoofnagle, A; Mason, M; ... Kowdley, KV Vitamin D Deficiency Is Associated With Increased Risk of Non-alcoholic Steatohepatitis in Adults With Non-alcoholic Fatty Liver Disease: Possible Role for MAPK and NF-kappaB? Am J Gastroenterol 111 6: 852-63; 2016

Whiteaker, JR; Halusa, GN; Hoofnagle, AN; Sharma, V; MacLean, B; Yan, P; Wrobel, JA; Kennedy, J; Mani, DR; ... Paulovich, AG Using the CPTAC Assay Portal to Identify and Implement Highly Characterized Targeted Proteomics Assays Methods Mol Biol 1410 223-36; 2016

Suchy-Dicey, AM; Laha, T; Hoofnagle, A; Newitt, R; Sirich, TL; Meyer, TW; Thummel, KE; Yanez, ND; Himmelfarb, J; ... Kestenbaum, BR Tubular Secretion in CKD J Am Soc Nephrol 27 7: 2148-55; 2016 PMC4926962

Hoofnagle, AN; Whiteaker, JR; Carr, SA; Kuhn, E; Liu, T; Massoni, SA; Thomas, SN; Townsend, RR; Zimmerman, LJ; ... Paulovich, AG Recommendations for the Generation, Quantification, Storage, and Handling of Peptides Used for Mass Spectrometry-Based Assays Clin Chem 62 1: 48-69; 2016 PMC4830481

Hoofnagle, AN; Laha, TJ; de Boer, IH ; Recalibration of 24,25-Dihydroxyvitamin D3 Results Based on NIST Standard Reference Material 972a Am J Kidney Dis 67 5: 812-3; 2016

Chatterjee, R; Zelnick, L; Mukamal, KJ; Nettleton, JA; Kestenbaum, BR; Siscovick, DS; Ix, JH; Tracy, R; Hoofnagle, AN; ... de Boer, IH Potassium Measures and Their Associations with Glucose and Diabetes Risk: The Multi-Ethnic Study of Atherosclerosis (MESA) PLoS One 11 6: e0157252; 2016 PMC4900670

Kennedy, JJ; Whiteaker, JR; Schoenherr, RM; Yan, P; Allison, K; Shipley, M; Lerch, M; Hoofnagle, AN; Baird, GS; ... Paulovich, AG Optimized Protocol for Quantitative Multiple Reaction Monitoring-Based Proteomic Analysis of Formalin-Fixed, Paraffin-Embedded Tissues J Proteome Res 15 8: 2717-28; 2016

Henderson, CM; Lutsey, PL; Misialek, JR; Laha, TJ; Selvin, E; Eckfeldt, JH; Hoofnagle, AN ; Measurement by a Novel LC-MS/MS Methodology Reveals Similar Serum Concentrations of Vitamin D-Binding Protein in Blacks and Whites Clin Chem 62 1: 179-87; 2016 PMC4698095

Henderson, CM; Vaisar, T; Hoofnagle, AN ; Isolating and Quantifying Plasma HDL Proteins by Sequential Density Gradient Ultracentrifugation and Targeted Proteomics Methods Mol Biol 1410 105-20; 2016

Netzel, BC; Grant, RP; Hoofnagle, AN; Rockwood, AL; Shuford, CM; Grebe, SK ; First Steps toward Harmonization of LC-MS/MS Thyroglobulin Assays Clin Chem 62 1: 297-9; 2016 PMC4794333

Beben, T; Ix, JH; Shlipak, MG; Sarnak, MJ; Fried, LF; Hoofnagle, AN; Chonchol, M; Kestenbaum, BR; de Boer, IH; ... Rifkin, DE Fibroblast Growth Factor-23 and Frailty in Elderly Community-Dwelling Individuals: The Cardiovascular Health Study J Am Geriatr Soc 64 2: 270-6; 2016

Annesley, TM; Cooks, RG; Herold, DA; Hoofnagle, AN ; Clinical Mass Spectrometry-Achieving Prominence in Laboratory Medicine Clin Chem 62 1: 1-3; 2016

Rebholz, CM; Grams, ME; Lutsey, PL; Hoofnagle, AN; Misialek, JR; Inker, LA; Levey, AS; Selvin, E; Hsu, CY; ... Chronic Kidney Disease Biomarkers Consortium Biomarkers of Vitamin D Status and Risk of ESRD Am J Kidney Dis 67 2: 235-42; 2016 PMC4724452

Isakova, T; Cai, X; Lee, J; Katz, R; Cauley, JA; Fried, LF; Hoofnagle, AN; Satterfield, S; Harris, TB; ... Health A. B. C. Study Associations of FGF23 With Change in Bone Mineral Density and Fracture Risk in Older Individuals J Bone Miner Res 31 4: 742-8; 2016

Hoofnagle, AN; Eckfeldt, JH; Lutsey, PL ; Vitamin D-Binding Protein Concentrations Quantified by Mass Spectrometry N Engl J Med 373 15: 1480-2; 2015 PMC4654614

Marsillach, J; Becker, JO; Vaisar, T; Hahn, BH; Brunzell, JD; Furlong, CE; de Boer, IH; McMahon, MA; Hoofnagle, AN; ... DCCT/EDIC Research Group Paraoxonase-3 is depleted from the high-density lipoproteins of autoimmune disease patients with subclinical atherosclerosis J Proteome Res 14 5: 2046-54; 2015 PMC4434596

de Boer, IH; Sachs, MC; Chonchol, M; Himmelfarb, J; Hoofnagle, AN; Ix, JH; Kremsdorf, RA; Lin, YS; Mehrotra, R; ... Kestenbaum, B Estimated GFR and circulating 24,25-dihydroxyvitamin D3 concentration: a participant-level analysis of 5 cohort studies and clinical trials Am J Kidney Dis 64 2: 187-97; 2014 PMC4111986

de Boer, IH; Sachs, M; Hoofnagle, AN; Utzschneider, KM; Kahn, SE; Kestenbaum, B; Himmelfarb, J ; Paricalcitol does not improve glucose metabolism in patients with stage 3-4 chronic kidney disease Kidney Int 83 2: 323-30; 2013 PMC3509239

Bosworth, C; Sachs, MC; Duprez, D; Hoofnagle, AN; Ix, JH; Jacobs, DR, Jr.; Peralta, CA; Siscovick, DS; Kestenbaum, B; ... de Boer, IH Parathyroid hormone and arterial dysfunction in the multi-ethnic study of atherosclerosis Clin Endocrinol (Oxf) 79 3: 429-36; 2013 PMC3664253

Kremsdorf, RA; Hoofnagle, AN; Kratz, M; Weigle, DS; Callahan, HS; Purnell, JQ; Horgan, AM; de Boer, IH; Kestenbaum, BR ; ... Kestenbaum, BR Effects of a high-protein diet on regulation of phosphorus homeostasis J Clin Endocrinol Metab 98 3: 1207-13; 2013 PMC3590482

Dickerson, JA; Schmeling, M; Hoofnagle, AN; Hoffman, NG ; Design and implementation of software for automated quality control and data analysis for a complex LC/MS/MS assay for urine opiates and metabolites Clin Chim Acta 415 290-4; 2013

Sachs, MC; Brunzell, JD; Cleary, PA; Hoofnagle, AN; Lachin, JM; Molitch, ME; Steffes, MW; Zinman, B; de Boer, IH; ... DCCT/EDIC Research Group Circulating vitamin D metabolites and subclinical atherosclerosis in type 1 diabetes Diabetes Care 36 8: 2423-9; 2013 PMC3714470

Blondon, M; Sachs, M; Hoofnagle, AN; Ix, JH; Michos, ED; Korcarz, C; Gepner, AD; Siscovick, DS; Kaufman, JD; ... de Boer, IH 25-Hydroxyvitamin D and parathyroid hormone are not associated with carotid intima-media thickness or plaque in the multi-ethnic study of atherosclerosis Arterioscler Thromb Vasc Biol 33 11: 2639-45; 2013 PMC3956469

Roth, CL; Elfers, CT; Figlewicz, DP; Melhorn, SJ; Morton, GJ; Hoofnagle, A; Yeh, MM; Nelson, JE; Kowdley, KV ; ... Kowdley, KV Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and Toll-like receptor activation Hepatology 55 4: 1103-11; 2012

Bosworth, CR; Levin, G; Robinson-Cohen, C; Hoofnagle, AN; Ruzinski, J; Young, B; Schwartz, SM; Himmelfarb, J; Kestenbaum, B; ... de Boer, IH The serum 24,25-dihydroxyvitamin D concentration, a marker of vitamin D catabolism, is reduced in chronic kidney disease Kidney Int 82 6: 693-700; 2012 PMC3434313

Becker, JO; Hoofnagle, AN ; Replacing immunoassays with tryptic digestion-peptide immunoaffinity enrichment and LC-MS/MS Bioanalysis 4 3: 281-90; 2012 PMC3699856

Hoofnagle, AN; Becker, JO; Oda, MN; Cavigiolio, G; Mayer, P; Vaisar, T ; Multiple-reaction monitoring-mass spectrometric assays can accurately measure the relative protein abundance in complex mixtures Clin Chem 58 4: 777-81; 2012 PMC3665768

de Boer, IH; Sachs, MC; Cleary, PA; Hoofnagle, AN; Lachin, JM; Molitch, ME; Steffes, MW; Sun, W; Zinman, B; ... DCCT/EDIC Research Group Circulating vitamin D metabolites and kidney disease in type 1 diabetes J Clin Endocrinol Metab 97 12: 4780-8; 2012 PMC3513544

Elsoe, S; Ahnstrom, J; Christoffersen, C; Hoofnagle, AN; Plomgaard, P; Heinecke, JW; Binder, CJ; Bjorkbacka, H; Dahlback, B; ... Nielsen, LB Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL Atherosclerosis 221 1: 91-7; 2012

Rubinow, KB; Snyder, CN; Amory, JK; Hoofnagle, AN; Page, ST ; Acute testosterone deprivation reduces insulin sensitivity in men Clin Endocrinol (Oxf) 76 2: 281-8; 2012 PMC3224202