Christian Roth


Seattle Children's Hospital



Research Interest: Central Regulation of Body Weight and Glucose Metabolism

DRC Publications

Nelson, JE; Roth, CL; Wilson, LA; Yates, KP; Aouizerat, B; Morgan-Stevenson, V; Whalen, E; Hoofnagle, A; Mason, M; ... Kowdley, KV Vitamin D Deficiency Is Associated With Increased Risk of Non-alcoholic Steatohepatitis in Adults With Non-alcoholic Fatty Liver Disease: Possible Role for MAPK and NF-kappaB? Am J Gastroenterol 111 6: 852-63; 2016

Henry, KE; Kerwood, DJ; Allis, DG; Workinger, JL; Bonaccorso, RL; Holz, GG; Roth, CL; Zubieta, J; Doyle, RP ; ... Doyle, RP Solution Structure and Constrained Molecular Dynamics Study of Vitamin B12 Conjugates of the Anorectic Peptide PYY(3-36) ChemMedChem 11 9: 1015-21; 2016 PMC4878914

Kuzma, JN; Cromer, G; Hagman, DK; Breymeyer, KL; Roth, CL; Foster-Schubert, KE; Holte, SE; Weigle, DS; Kratz, M ; ... Kratz, M No differential effect of beverages sweetened with fructose, high-fructose corn syrup, or glucose on systemic or adipose tissue inflammation in normal-weight to obese adults: a randomized controlled trial Am J Clin Nutr 104 2: 306-14; 2016 PMC4962158

Roth, CL; Elfers, C; Lass, N; Reinehr, T ; Betatrophin: no relation to glucose metabolism or weight status in obese children before and after lifestyle intervention Pediatr Diabetes 2016

Henry, KE; Elfers, CT; Burke, RM; Chepurny, OG; Holz, GG; Blevins, JE; Roth, CL; Doyle, RP ; Vitamin B12 conjugation of peptide-YY(3-36) decreases food intake compared to native peptide-YY(3-36) upon subcutaneous administration in male rats Endocrinology 156 5: 1739-49; 2015 PMC4398759

Hourigan, SK; Abrams, S; Yates, K; Pfeifer, K; Torbenson, M; Murray, K; Roth, CL; Kowdley, K; Scheimann, AO; ... Nash, CRN Relation between vitamin D status and nonalcoholic fatty liver disease in children J Pediatr Gastroenterol Nutr 60 3: 396-404; 2015 PMC4341959

Kuzma, JN; Cromer, G; Hagman, DK; Breymeyer, KL; Roth, CL; Foster-Schubert, KE; Holte, SE; Callahan, HS; Weigle, DS; ... Kratz, M No difference in ad libitum energy intake in healthy men and women consuming beverages sweetened with fructose, glucose, or high-fructose corn syrup: a randomized trial Am J Clin Nutr 102 6: 1373-80; 2015 PMC4658464

Roth, CL ; Hypothalamic Obesity in Craniopharyngioma Patients: Disturbed Energy Homeostasis Related to Extent of Hypothalamic Damage and Its Implication for Obesity Intervention J Clin Med 4 9: 1774-97; 2015 PMC4600159

Melhorn, SJ; Tyagi, V; Smeraglio, A; Roth, CL; Schur, EA ; Initial evidence that GLP-1 receptor blockade fails to suppress postprandial satiety or promote food intake in humans Appetite 82 85-90; 2014 PMC4171349

Roth, CL; Elfers, C; Gebhardt, U; Muller, HL; Reinehr, T ; Brain-derived neurotrophic factor and its relation to leptin in obese children before and after weight loss Metabolism 62 2: 226-34; 2013

Roth, CL; Elfers, CT; Figlewicz, DP; Melhorn, SJ; Morton, GJ; Hoofnagle, A; Yeh, MM; Nelson, JE; Kowdley, KV ; ... Kowdley, KV Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and Toll-like receptor activation Hepatology 55 4: 1103-11; 2012

Roth, CL; Sathyanarayana, S ; Mechanisms affecting neuroendocrine and epigenetic regulation of body weight and onset of puberty: potential implications in the child born small for gestational age (SGA) Rev Endocr Metab Disord 13 2: 129-40; 2012

Elfers, CT; Simmons, JH; Roth, CL ; Glucagon-like peptide-1 agonist exendin-4 leads to reduction of weight and caloric intake in a rat model of hypothalamic obesity Horm Res Paediatr 78 1: 47-53; 2012

Roth, CL; Aylward, E; Liang, O; Kleinhans, NM; Pauley, G; Schur, EA ; Functional neuroimaging in craniopharyngioma: a useful tool to better understand hypothalamic obesity? Obes Facts 5 2: 243-53; 2012