Jonathan Himmelfarb

Professor

Harborview Medical Center

Medicine

Email: himmej@u.washington.edu

Research Interest: Clinical Trials and Large-Scale Epidemiologic Studies, Complications of Diabetes

DRC Publications

Gura, V; Rivara, MB; Bieber, S; Munshi, R; Smith, NC; Linke, L; Kundzins, J; Beizai, M; Ezon, C; ... Himmelfarb, J A wearable artificial kidney for patients with end-stage renal disease JCI Insight 1 8: 2016 PMC4936831

Dember, LM; Imrey, PB; Duess, MA; Hamburg, NM; Larive, B; Radeva, M; Himmelfarb, J; Kraiss, LW; Kusek, JW; ... Hemodialysis Fistula Maturation Study GroupFeldman, HFKSLKSMAYuTWMMLAE-KCPTeC-NH Vascular Function at Baseline in the Hemodialysis Fistula Maturation Study J Am Heart Assoc 5 7: 2016

Suchy-Dicey, AM; Laha, T; Hoofnagle, A; Newitt, R; Sirich, TL; Meyer, TW; Thummel, KE; Yanez, ND; Himmelfarb, J; ... Kestenbaum, BR Tubular Secretion in CKD J Am Soc Nephrol 27 7: 2148-55; 2016 PMC4926962

Craciun, FL; Bijol, V; Ajay, AK; Rao, P; Kumar, RK; Hutchinson, J; Hofmann, O; Joshi, N; Luyendyk, JP; ... Vaidya, VS RNA Sequencing Identifies Novel Translational Biomarkers of Kidney Fibrosis J Am Soc Nephrol 27 6: 1702-13; 2016 PMC4884105

Xie, Y; Maziarz, M; Tuot, DS; Chertow, GM; Himmelfarb, J; Hall, YN ; Risk prediction to inform surveillance of chronic kidney disease in the US Healthcare Safety Net: a cohort study BMC Nephrol 17 1: 57; 2016 PMC4898308

Young, BA; Katz, R; Boulware, LE; Kestenbaum, B; de Boer, IH; Wang, W; Fulop, T; Bansal, N; Robinson-Cohen, C; ... Correa, A Risk Factors for Rapid Kidney Function Decline Among African Americans: The Jackson Heart Study (JHS) Am J Kidney Dis 68 2: 229-39; 2016

Mehrotra, R; Soohoo, M; Rivara, MB; Himmelfarb, J; Cheung, AK; Arah, OA; Nissenson, AR; Ravel, V; Streja, E; ... Kalantar-Zadeh, K Racial and Ethnic Disparities in Use of and Outcomes with Home Dialysis in the United States J Am Soc Nephrol 27 7: 2123-34; 2016 PMC4926974

Ligresti, G; Nagao, RJ; Xue, J; Choi, YJ; Xu, J; Ren, S; Aburatani, T; Anderson, SK; MacDonald, JW; ... Zheng, Y A Novel Three-Dimensional Human Peritubular Microvascular System J Am Soc Nephrol 27 8: 2370-81; 2016

Gamboa, JL; Billings, FTt; Bojanowski, MT; Gilliam, LA; Yu, C; Roshanravan, B; Roberts, LJ, 2nd; Himmelfarb, J; Ikizler, TA; ... Brown, NJ Mitochondrial dysfunction and oxidative stress in patients with chronic kidney disease Physiol Rep 4 9: 2016 PMC4873632

Bansal, N; Katz, R; Himmelfarb, J; Afkarian, M; Kestenbaum, B; de Boer, IH; Young, B ; Markers of kidney disease and risk of subclinical and clinical heart failure in African Americans: the Jackson Heart Study Nephrol Dial Transplant 2016

de Boer, IH; Zelnick, L; Afkarian, M; Ayers, E; Curtin, L; Himmelfarb, J; Ikizler, TA; Kahn, SE; Kestenbaum, B; ... Utzschneider, K Impaired Glucose and Insulin Homeostasis in Moderate-Severe CKD J Am Soc Nephrol 2016

Hahn, WO; Mikacenic, C; Price, BL; Harju-Baker, S; Katz, R; Himmelfarb, J; Wurfel, MM; Liles, WC ; Host derived biomarkers of inflammation, apoptosis, and endothelial activation are associated with clinical outcomes in patients with bacteremia and sepsis regardless of microbial etiology Virulence 7 4: 387-94; 2016 PMC4871669

Yamaura, Y; Chapron, BD; Wang, Z; Himmelfarb, J; Thummel, KE ; Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism Drug Metab Dispos 44 3: 329-35; 2016 PMC4767385

Ikizler, HO; Zelnick, L; Ruzinski, J; Curtin, L; Utzschneider, KM; Kestenbaum, B; Himmelfarb, J; de Boer, IH ; Dietary Acid Load is Associated With Serum Bicarbonate but not Insulin Sensitivity in Chronic Kidney Disease J Ren Nutr 26 2: 93-102; 2016 PMC4762747

Afkarian, M; Katz, R; Bansal, N; Correa, A; Kestenbaum, B; Himmelfarb, J; de Boer, IH; Young, B ; Diabetes, Kidney Disease, and Cardiovascular Outcomes in the Jackson Heart Study Clin J Am Soc Nephrol 11 8: 1384-91; 2016

Pavkovic, M; Robinson-Cohen, C; Chua, AS; Nicoara, O; Cardenas-Gonzalez, M; Bijol, V; Ramachandran, K; Hampson, L; Pirmohamed, M; ... Vaidya, VS Detection of Drug-Induced Acute Kidney Injury in Humans Using Urinary KIM-1, miR-21, -200c, and -423 Toxicol Sci 152 1: 205-13; 2016

Roshanravan, B; Kestenbaum, B; Gamboa, J; Jubrias, SA; Ayers, E; Curtin, L; Himmelfarb, J; de Boer, IH; Conley, KE ; ... Conley, KE CKD and Muscle Mitochondrial Energetics Am J Kidney Dis 2016

Rivara, MB; Soohoo, M; Streja, E; Molnar, MZ; Rhee, CM; Cheung, AK; Katz, R; Arah, OA; Nissenson, AR; ... Mehrotra, R Association of Vascular Access Type with Mortality, Hospitalization, and Transfer to In-Center Hemodialysis in Patients Undergoing Home Hemodialysis Clin J Am Soc Nephrol 11 2: 298-307; 2016 PMC4741041

Robinson-Cohen, C; Katz, R; Price, BL; Harju-Baker, S; Mikacenic, C; Himmelfarb, J; Liles, WC; Wurfel, MM ; Association of markers of endothelial dysregulation Ang1 and Ang2 with acute kidney injury in critically ill patients Crit Care 20 1: 207; 2016 PMC4930837

Mitchell, KH; Carlbom, D; Caldwell, E; Leary, PJ; Himmelfarb, J; Hough, CL ; Volume Overload: Prevalence, Risk Factors, and Functional Outcome in Survivors of Septic Shock Ann Am Thorac Soc 12 12: 1837-44; 2015 PMC4722831

Afkarian, M; Zelnick, LR; Ruzinski, J; Kestenbaum, B; Himmelfarb, J; de Boer, IH; Mehrotra, R ; Urine matrix metalloproteinase-7 and risk of kidney disease progression and mortality in type 2 diabetes J Diabetes Complications 29 8: 1024-31; 2015

Kuttykrishnan, S; Kalantar-Zadeh, K; Arah, OA; Cheung, AK; Brunelli, S; Heagerty, PJ; Katz, R; Molnar, MZ; Nissenson, A; ... Mehrotra, R Predictors of treatment with dialysis modalities in observational studies for comparative effectiveness research Nephrol Dial Transplant 30 7: 1208-17; 2015 PMC4560036

Maziarz, M; Black, RA; Fong, CT; Himmelfarb, J; Chertow, GM; Hall, YN ; Evaluating risk of ESRD in the urban poor J Am Soc Nephrol 26 6: 1434-42; 2015 PMC4446879

Yeung, CK; Billings, FTt; Claessens, AJ; Roshanravan, B; Linke, L; Sundell, MB; Ahmad, S; Shao, B; Shen, DD; ... Himmelfarb, J Coenzyme Q10 dose-escalation study in hemodialysis patients: safety, tolerability, and effect on oxidative stress BMC Nephrol 16 183; 2015 PMC4630830

Shao, B; de Boer, I; Tang, C; Mayer, PS; Zelnick, L; Afkarian, M; Heinecke, JW; Himmelfarb, J ; A Cluster of Proteins Implicated in Kidney Disease Is Increased in High-Density Lipoprotein Isolated from Hemodialysis Subjects J Proteome Res 14 7: 2792-806; 2015 PMC4636116

Hall, YN; Himmelfarb, J ; Border Health: State-Level Variation in Predialysis Nephrology Care Clin J Am Soc Nephrol 10 11: 1892-4; 2015 PMC4633793

Mikacenic, C; Hahn, WO; Price, BL; Harju-Baker, S; Katz, R; Kain, KC; Himmelfarb, J; Liles, WC; Wurfel, MM ; ... Wurfel, MM Biomarkers of Endothelial Activation Are Associated with Poor Outcome in Critical Illness PLoS One 10 10: e0141251; 2015 PMC4619633

Bhatraju, P; Hsu, C; Mukherjee, P; Glavan, BJ; Burt, A; Mikacenic, C; Himmelfarb, J; Wurfel, M ; Associations between single nucleotide polymorphisms in the FAS pathway and acute kidney injury Crit Care 19 368; 2015 PMC4610046

Afkarian, M; Hirsch, IB; Tuttle, KR; Greenbaum, C; Himmelfarb, J; de Boer, IH ; Urinary excretion of RAS, BMP, and WNT pathway components in diabetic kidney disease Physiol Rep 2 5: e12010; 2014 PMC4098738

Robinson-Cohen, C; Hall, YN; Katz, R; Rivara, MB; de Boer, IH; Kestenbaum, BR; Himmelfarb, J ; Self-rated health and adverse events in CKD Clin J Am Soc Nephrol 9 12: 2044-51; 2014 PMC4255401

Dember, LM; Imrey, PB; Beck, GJ; Cheung, AK; Himmelfarb, J; Huber, TS; Kusek, JW; Roy-Chaudhury, P; Vazquez, MA; ... Hemodialysis Fistula Maturation Study, G Objectives and design of the hemodialysis fistula maturation study Am J Kidney Dis 63 1: 104-12; 2014 PMC4134933

de Boer, IH; Sachs, MC; Chonchol, M; Himmelfarb, J; Hoofnagle, AN; Ix, JH; Kremsdorf, RA; Lin, YS; Mehrotra, R; ... Kestenbaum, B Estimated GFR and circulating 24,25-dihydroxyvitamin D3 concentration: a participant-level analysis of 5 cohort studies and clinical trials Am J Kidney Dis 64 2: 187-97; 2014 PMC4111986

de Boer, IH; Sachs, M; Hoofnagle, AN; Utzschneider, KM; Kahn, SE; Kestenbaum, B; Himmelfarb, J ; Paricalcitol does not improve glucose metabolism in patients with stage 3-4 chronic kidney disease Kidney Int 83 2: 323-30; 2013 PMC3509239

Afkarian, M; Sachs, MC; Kestenbaum, B; Hirsch, IB; Tuttle, KR; Himmelfarb, J; de Boer, IH ; Kidney disease and increased mortality risk in type 2 diabetes J Am Soc Nephrol 24 2: 302-8; 2013 PMC3559486

Kelly, EJ; Wang, Z; Voellinger, JL; Yeung, CK; Shen, DD; Thummel, KE; Zheng, Y; Ligresti, G; Eaton, DL; ... Himmelfarb, J Innovations in preclinical biology: ex vivo engineering of a human kidney tissue microperfusion system Stem Cell Res Ther 4 Suppl 1 S17; 2013 PMC4029535

Mehrotra, R; Himmelfarb, J ; Dialysis in 2012: Could longer and more frequent haemodialysis improve outcomes? Nat Rev Nephrol 9 2: 74-5; 2013

Bosworth, CR; Levin, G; Robinson-Cohen, C; Hoofnagle, AN; Ruzinski, J; Young, B; Schwartz, SM; Himmelfarb, J; Kestenbaum, B; ... de Boer, IH The serum 24,25-dihydroxyvitamin D concentration, a marker of vitamin D catabolism, is reduced in chronic kidney disease Kidney Int 82 6: 693-700; 2012 PMC3434313

Roshanravan, B; Khatri, M; Robinson-Cohen, C; Levin, G; Patel, KV; de Boer, IH; Seliger, S; Ruzinski, J; Himmelfarb, J; ... Kestenbaum, B A prospective study of frailty in nephrology-referred patients with CKD Am J Kidney Dis 60 6: 912-21; 2012 PMC3491110