Global WACh

Family Planning


January 12, 2017

Building evidence for HIV risk with contraceptive methods

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Renee Heffron

Renee Heffron is the grant’s primary investigator.

Dr. Renee Heffron, co-director of our Global WACh Family Planning Working Group, has received new funding from the NIH to tie into the Evidence for Contraceptive Options and HIV Outcomes (ECHO) Study. ECHO enrolls participants in sub-Saharan Africa for a randomized trial of three equally safe and effective contraceptive methods: the copper T intrauterine device (IUD); injectable depo-medroxyprogesterone acetate (DMPA), also known as the Depo shot; and the Jadelle implant.

For sub-Saharan African women at risk for becoming infected with HIV, it is important to build knowledge around potential associations of specific contraceptives with HIV acquisition. A number of observational studies have examined whether or not use of hormonal methods affects the risk of HIV acquisition. Some of these studies suggest that injectable methods—particularly the Depo shot—might increase a woman’s risk of acquiring HIV infection, while other studies show no association. The World Health Organization continuously reviews the information about contraceptives and, thus far, has determined that all of the contraceptives that will be used in the ECHO Study are safe for women at risk of HIV risk infection, but that more research is needed.

contraception

Photo by echo-consortium.com

With this additional funding, ECHO will now begin to measure biological markers periodically over the three-year trial period associated with the Depo shot, the Jadelle implant, and the copper IUD. These markers include vaginal microbiome, markers of inflammation, HIV target cells, protein signatures, and transcriptome to identify differences between women using the different contraceptives.

Read the full story from ASPPH here.


July 18, 2016

Global WACh Family Planning Study Completes its First Day of Training

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The unmet need for contraception in Kenya in the postpartum period, or months following childbirth, is high.  This unmet need contributes to poor maternal and child health outcomes, and impedes women’s empowerment.

Mobile WACh XY is a two-arm randomized controlled trial (RCT) comparing the effect of bidirectional SMS dialogue vs. control on highly effective contraceptive use at 6 months postpartum among  individual women and couple dyads in Nyanza Province, Kenya.  The study builds upon the experience of other Global WACh mHealth studies using a text messaging platform that pushes automated messages containing critical information at crucial times and allows users to respond and converse with a health professional about their individual needs.  Mobile WACh XY differentiates itself in the family planning arena by including an emphasis on male partner involvement and couple communication. Male partners need to be invited to participate in the study, given the desire to include men while continuing to promote women’s reproductive autonomy.

Mobile WACh XY team poses for a photo on their second day of training

Mobile WACh XY team poses for a photo on their second day of training

The XY team is led by Drs. Elizabeth Harrington, Jennifer Unger and John Kinuthia.  This Global WACh study team completed its first week of training in Kisumu, Kenya last week.

Over the next 6 months they will enroll 220 women in the study, and up to 220 men—depending on female participants’ preferences.  Information gathered will provide insight into the effectiveness of an mHealth strategy to help meet women’s and couples’ postpartum contraceptive needs, and have policy implications for postpartum family planning programming.

Congratulations to everyone involved!  We look forward to sharing your progress.