August 24, 2020

SARS-CoV-2 Infections Among Children in the Biospecimens from Respiratory Virus-Exposed Kids (BRAVE Kids) Study

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): children, risk factors

• [pre-print, not peer-reviewed] In a cohort of children and adolescents who had close contact with a person with known SARS-CoV-2 infection (n=382), SARS-CoV-2-infected children (n=293) were more likely to be Hispanic (88% vs 57%), less likely to have asthma (6% vs 17%), and more likely to have an infected sibling contact (49% vs 29%), compared to uninfected children (n=89). Children between 6 and 13 years were frequently asymptomatic (39%) and less likely to have respiratory symptoms (29%) than younger children (48%) or adolescents (60%). Adolescents were more likely than children 6 to 13 to report flu-like (61% vs 39%), gastrointestinal (27% vs 9%), and sensory symptoms (42% vs 9%), and they had more prolonged symptom duration (7 days vs 4 days). No differences were found in nasopharyngeal viral load either by age or between symptomatic and asymptomatic children.

Hurst et al. (Aug 21, 2020). SARS-CoV-2 Infections Among Children in the Biospecimens from Respiratory Virus-Exposed Kids (BRAVE Kids) Study. Pre-print downloaded August 21 from https://doi.org/10.1101/2020.08.18.20166835