September 2, 2020

Serological Identification of SARS-CoV-2 Infections among Children Visiting a Hospital during the Initial Seattle Outbreak

Category: Article Summary

Topic: Testing and Treatment

Keywords (Tags): children, immunity, washington

• Six of eight children who had SARS-CoV-2 antibodies detected in leftover clinical samples had not been suspected of having COVID-19. Dingens et al. screened 1,775 leftover serum samples from children seeking medical care at Seattle Children’s Hospital during the early Seattle outbreak period and found one child was seropositive with SARS-CoV-2 in March and seven were seropositive in April, for a seroprevalence of 1% during this period among this population of children seeking care. Only two of the children with positive antibodies had tested positive for SARS-CoV-2 by RT-PCR. [EDITORIAL NOTE: A summary of a pre-print version of this manuscript appeared in the Lit Rep on May 28]

Dingens et al. (Sept 1, 2020). Serological Identification of SARS-CoV-2 Infections among Children Visiting a Hospital during the Initial Seattle Outbreak. Nature Communications. https://doi.org/10.1038/s41467-020-18178-1