Alliance for Pandemic Preparedness

October 7, 2020

A Potential Impact of Physical Distancing on Physical and Mental Health. A Rapid Narrative Umbrella Review of Meta-Analyses on the Link between Social Isolation and Health

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  • [Pre-print, not peer-reviewed] A narrative synthesis of 25 meta-analyses including 692 primary studies with more than 3 million individuals indicated that social isolation is associated with a range of poor physical and mental health outcomes, including chronic physical symptoms, frailty, coronary heart disease, malnutrition, hospital readmission, reduced vaccine uptake, early mortality, depression, social anxiety, psychosis, cognitive impairment in later life, and suicidal ideation.

Morina et al. (Oct 7, 2020). A Potential Impact of Physical Distancing on Physical and Mental Health. A Rapid Narrative Umbrella Review of Meta-Analyses on the Link between Social Isolation and Health. Pre-print downloaded Oct 7 from https://doi.org/10.1101/2020.10.06.20207571