April 29, 2021

Association of Maternal SARS-CoV-2 Infection in Pregnancy With Neonatal Outcomes

Category: Article Summary

Topic: Public Health Policy and Practice

Keywords (Tags): infant, pregnancy, public health

• SARS-CoV-2 infection in pregnancy (from conception to 1 week after birth) was significantly associated with a 1.4-fold higher risk of any neonatal respiratory disorder after matching for maternal characteristics in a nationwide cohort study in Sweden (n=88,159 infants). Admission for neonatal care, respiratory distress syndrome, and hyperbilirubinemia were also associated with maternal SARS-CoV-2 test positivity. In contrast, neonatal mortality, breastfeeding rates at discharge, and length of stay in neonatal care were not associated with maternal positivity. 1.6% of infants (n=2,323) were delivered by SARS-CoV-2 positive mothers, of which 21 (0.9%) tested positive.

Norman et al. (Apr 29, 2021). Association of Maternal SARS-CoV-2 Infection in Pregnancy With Neonatal Outcomes. JAMA. https://doi.org/10.1001/jama.2021.5775