Alliance for Pandemic Preparedness

December 7, 2020

A Meta-Analysis on the Role of Children in SARS-CoV-2 in Household Transmission Clusters

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A meta-analysis of the role of children in SARS-CoV-2 household transmission identified 213 transmission clusters from 12 countries, and found that only 8 clusters (3.8%) had a pediatric index case. Asymptomatic index cases were associated with a lower secondary attack rate in contacts than symptomatic index cases (RR 0.17). The secondary attack rate was also lower among pediatric than adult household contacts (RR, 0.62). 

Zhu et al. (Dec 6, 2020). A Meta-Analysis on the Role of Children in SARS-CoV-2 in Household Transmission Clusters. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciaa1825