October 2, 2020
Sequelae of COVID-19 in Hospitalized Children
A study of 28 hospitalized pediatric patients with COVID-19 in Turin, Italy found that all participants had nasal swabs negative for SARS-CoV-2 by PCR one month after discharge. Lung ultrasound findings had normalized within 5 weeks from hospital discharge in the majority of patients. 20 out of 24 patients developed anti-SARS-CoV-2 IgG at the follow-up…
Symptom Characterization and Outcomes of Sailors in Isolation After a COVID-19 Outbreak on a US Aircraft Carrier
Among sailors who disembarked from the USS Theodore Roosevelt, 736 out of 4,085 (18%) were positive for SARS-CoV-2, of whom 590 (80%) were symptomatic. Six sailors were hospitalized and one died. Loss of taste and smell were reported commonly. The authors note that in confined areas with young essential workers, COVID-19 symptoms may not be…
Case Series of Multisystem Inflammatory Syndrome in Adults Associated with SARS-CoV-2 Infection — United Kingdom and United States, March – August 2020
Morris et al. report 27 cases of multisystem inflammatory syndrome (MIS) associated with SARS-CoV-2 infection in adults that have been reported to CDC or published in the literature. MIS has been previously described among children and adolescents. MIS differs from typical manifestations of severe COVID-19 in that patients with MIS have minimal respiratory symptoms, hypoxemia,…
Waning of SARS-CoV-2 RBD Antibodies in Longitudinal Convalescent Plasma Samples within Four Months after Symptom Onset
A decrease in anti-RBD antibodies was observed over time in a study of individuals who had recovered from SARS-CoV-2 and who gave repeated blood donations. The study determined that the decline was not due to repeated donations, but rather that the anti-RBD response wanes over time of convalescence. The response was found to be relatively…
Intention to Participate in a COVID-19 Vaccine Clinical Trial and to Get Vaccinated against COVID-19 in France during the Pandemic
Nearly 75% of respondents in an online survey in France said they were likely to get a COVID-19 vaccine, and almost half indicated they might agree to participate in a clinical trial for the vaccine. The anonymous online survey indicated that healthcare workers were more likely to report that they would get vaccinated or participate…
Effectiveness of Tests to Detect the Presence of SARS-CoV-2 Virus, and Antibodies to SARS-CoV-2, to Inform COVID-19 Diagnosis: A Rapid Systematic Review
A rapid systematic review of both SARS-CoV-2 virus and antibody testing found a sensitivity of 87.8% for an initial RT-PCR test, while sensitivity of antibody tests ranged from 18.4% to 96.1% and specificity ranged from 88.9% to 100%. The authors note that estimates of diagnostic accuracy should be interpreted cautiously due to the lack of…
Viral Genomes Reveal Patterns of the SARS-CoV-2 Outbreak in Washington State
[Pre-print, not peer reviewed] The 614G viral variant of SARS-CoV-2 has been hypothesized to be more transmissible than other strains, but findings from Washington State indicate that the increasing dominance of 614G in the state is more likely due to mobility patterns and the effect of control measures rather than viral transmissibility factors. Sequencing of…
COVID-19 Literature Situation Report Oct. 2, 2020
A study of viral genomes from Washington State indicated that the timing of mitigation strategies and repeated introductions of viral lineages into the state likely shaped the relative distribution of different lineages of SARS-CoV-2, rather than differences in transmissibility between variants of the virus.
October 1, 2020
National Trends of Cases of COVID-19 in Children Based on US State Health Department Data
As of Sept 10, 2020, there were 549,432 cumulative COVID-19 cases in the US among children (729 cases per 100,000 children). The geographic focus of case growth shifted from the Northeast in April to the South and West in June and to the Midwest in July. Over time, the proportion of pediatric COVID-19 cases has…
Opioid Overdose–Related Emergency Department Visits and Accidental Deaths during the COVID-19 Pandemic
Emergency room visits and deaths related to opioid overdose increased in San Francisco during the first weeks of COVID-19 pandemic (January 1 through April 18, 2020). Visits related to opioid overdose were 2.5 patients per day during this period vs. 1.4 prior, and deaths were 1.47 per day during this period vs. 0.95 prior. Rodda et…
Previous page Next page