Article Summary
November 25, 2020
Retrospective Cohort Study of Admission Timing and Mortality Following COVID-19 Infection in England
A retrospective cohort study of 6,068 COVID-19 patients in England found that each additional day between symptom onset and hospital admission was associated with a 1% increase in the risk of mortality. Healthcare workers, obese people, and Black, Asian, and other ethnic minorities were more likely to experience later hospital admission, which the authors suggest…
Educational Gains of in‐person vs. Distance Learning in Primary and Secondary Schools: A Natural Experiment during the COVID‐19 Pandemic School Closures in Switzerland
Educational gains among primary school students in Switzerland were cut in half with distance learning during school closures due to the COVID-19 pandemic. An analysis of educational gains during the 8 weeks of school closures related to the COVID‐19 pandemic in Switzerland, compared to the prior 8 weeks, found high heterogeneity in learning processes between individual primary…
Reducing Travel-Related SARS-CoV-2 Transmission with Layered Mitigation Measures Symptom Monitoring Quarantine and Testing
[Pre-print; not peer-reviewed] A model built to assess the relative impact of symptom monitoring, testing, and quarantine practices on transmission of SARS-CoV-2 by infected travelers suggests that quarantining for 14 days almost eliminates risk of transmission. The effectiveness of testing depended on timing and quality of the test, with the combination of a pre-travel test…
November 24, 2020
Socio-Economic Status and COVID-19–Related Cases and Fatalities
An analysis of US county-level COVID-19 data and a Distressed Communities Index (DCI) score (n=3,127 counties) found that severely distress counties (DCI score >75) had a small total number of COVID-19 deaths but more deaths per capita. Socio-economic determinants of health most associated with higher per capita cases and fatalities were the percentage of adults…
Psychological Distress and COVID-19–Related Stressors Reported in a Longitudinal Cohort of US Adults in April and July 2020
A nationally representative longitudinal survey of US adults (n=1,337) found 13% of respondents reported serious psychological distress in July 2020, relative to 14% in April 2020. At both time points, levels of reported serious distress were highest among adults aged 18-29 years, those with income less than $35,000, and Hispanic individuals. Among those with serious…
Risk Factors for Depression, Anxiety, and PTSD Symptoms in Perinatal Women during the COVID-19 Pandemic
A cross-sectional survey of 1,123 pregnant and postpartum women in the US (second trimester of pregnancy through 6 months after delivery) conducted from May to August 2020 found that 36% reported clinically significant levels of depression, 23% reported generalized anxiety, and 10% reported PTSD. Self-reported pre-existing mental health diagnoses increased the likelihood of scoring above…
Severe COVID-19 Infection and Pediatric Comorbidities: A Systematic Review and Meta-Analysis
A systematic review and meta-analysis (n=47 studies) found that compared to healthy children, children with comorbidities had a 1.8-fold increase in risk for sever COVID-19. Underlying conditions and obesity were also associated with higher risk of COVID-19-associated mortality. Tsankov et al. (Nov 20, 2020). Severe COVID-19 Infection and Pediatric Comorbidities: A Systematic Review and…
Surviving COVID-19 After Hospital Discharge: Symptom, Functional, and Adverse Outcomes of Home Health Recipients
A retrospective observational cohort study of COVID-19 survivors admitted to home health care (HHC) post-hospitalization in New York City (n=1,409) found that after an average of 32 days in HHC, most patients experienced significant improvements in symptoms and function. 94% were discharged from HHC. Risk of rehospitalization or death (137 rehospitalizations, 11 deaths) was associated…
Assessment of 135 794 Pediatric Patients Tested for Severe Acute Respiratory Syndrome Coronavirus 2 Across the United States
In a cohort of US pediatric patients (n=135,794; mean age=8.8), 5,374 (4%) tested positive for SARS-CoV-2, of whom 359 (7%) were hospitalized and 8 died (case fatality proportion = 0.2%). Despite lower rates of testing compared with White patients, participants of Black, Hispanic, and Asian race/ethnicity were more likely to have positive test results. Older…
Stable Neutralizing Antibody Levels Six Months after Mild and Severe COVID-19 Episode
Pre-print, not peer reviewed] Longitudinal analysis of 210 Spanish patients followed for up to 242 days showed that individuals with mild or asymptomatic SARS-CoV-2 infection experienced a negligible decay in neutralizing antibody activity that persisted for six months after symptom onset, while hospitalized individuals showed an initial rapid decline in neutralizing titers that significantly slowed…
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