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February 24, 2020
Estimating the case fatality ratio of the COVID-19 epidemic in China
A new study estimates the case fatality risk in Wuhan to be 8.71% (95% CI: 79.5%-9.64%) compared to 1.21% (95% CI: 1.07%-1.40%) in other areas of China. Wang et al. (Feb 22, 2020). Estimating the case fatality ratio of the COVID-19 epidemic in China. Pre-print downloaded Feb 23 from https://doi.org/10.1101/2020.02.17.20023630
February 21, 2020
Psychological responses, behavioral changes and public perceptions during the early phase of the COVID-19 outbreak in China: a population based cross-sectional survey
510 persons from Wuhan and 501 persons from Shanghai completed phone interviews asking about symptoms of anxiety and also changes in behaviors related to COVID-19, such as increased hand washing, use of masks, and avoidance of going out. Citizens near the epicenter (Wuhan) reported significantly greater symptoms of moderate to severe anxiety than those…
oronavirus: home testing pilot launched in London to cut hospital visits and ambulance use
In London, public health officials are piloting a new in-home COVID-19 test among people determined not to require immediate hospitalization. Mahase (Feb 14, 2020). Coronavirus: home testing pilot launched in London to cut hospital visits and ambulance use. BMJ. https://doi.org/10.1136/bmj.m621
Clinical Characteristics and Progression of 2019 Novel Coronavirus-1 Infected Patients 2 Concurrent Acute Respiratory Distress Syndrome
Clinical characteristics are described for 109 COVID-19 patients admitted to Central Hospital of Wuhan. Patients with acute respiratory distress syndrome (ARDS) were more likely to have co-existing conditions, such as diabetes and cerebrovascular and chronic kidney disease than patients without ARDS. Severity of ARDS was also associated with higher risk of death. Liu et al….
Kidney impairment is associated with in-hospital death of COVID-19 patients
A study of 710 COVID-19 patients found elevated prevalence of kidney impairment and a higher risk of in-hospital death among those with kidney impairment. Cheng et al. (Feb 20, 2020). Kidney impairment is associated with in-hospital death of COVID-19 patients. Pre-print downloaded Feb 21 from https://doi.org/10.1101/2020.02.18.20023242
Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study
Among critically ill COVID-19 pneumonia patients, mortality is high, especially for those with comorbidities. Survival after ICU admission appears to be around 1-2 weeks among these patients. Yang et al. (Feb 21, 2020). Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. The Lancet Respir…
Estimating the cure rate and case fatality rate of the ongoing epidemic COVID-19
Diao et al. estimate the cure rate and case fatality for COVID-19 patients in Wuhan and the rest of mainland China using data on hospital discharges to support more precise modelling. They estimate that in mainland China, 93% of patients recover compared to 87% in Wuhan. These numbers suggest a case fatality among known patients…
Estimating number of global importations of COVID-19 from Wuhan, risk of transmission outside mainland China and COVID-19 introduction index between countries outside mainland China
Accounting for potential unrecorded migration, these authors estimate the scope of COVID-19 importations in countries outside of China. They compare reported and estimated number of cases and describe countries that may be at elevated risk of local transmission. The U.S. is among the countries with higher estimated risk of a local outbreak. Sun et al….
COVID-19 in Singapore—Current Experience: Critical Global Issues That Require Attention and Action
Singapore’s proactive public health response to COVID-19 is described with reference to seven critical issues that require global attention to further curb the spread of the outbreak. Among these are improved understanding of the epidemiological and clinical features of the virus, identification of effective treatment options and vaccines, and better communication and support strategies for…
February 20, 2020
Mental health care for medical staff in China during the COVID-19 outbreak
Mental health services for healthcare workers were quickly established for 5 large healthcare organizations in China. These included psychologist teams and online support. However, medical staff refused to participate in the psychological resources offered, explaining that they did not meet their actual needs. These included feeling more exhausted than worried, not wanting families to worry,…
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