Alliance for Pandemic Preparedness

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February 12, 2020

COVID-19 and psoriasis: is it time to limit treatment with immunosuppressants? A call for action

The authors stress the importance of a therapeutic reassessment of all psoriatic patients because immunosuppressive drugs can weaken the immune system making these patients more susceptible to opportunistic infections.  Conforti et al. (Mar 11, 2020). COVID-19 and psoriasis: is it time to limit treatment with immunosuppressants? A call for action. Dermatologic Therapy. https://doi.org/10.1111/dth.13298 


February 11, 2020

Substance Abuse and Mental Health Services Administration Resources

The Substance Abuse and Mental Health Services Administration has three helpful resources related to mental health during infectious disease outbreaks. These were developed in response to previous events to support community members and may be particularly helpful as WA continues to stand up quarantine processes for 2019-nCoV outbreak response.  Taking Care of Your Behavioral Health:…


Emerging threats from zoonotic coronaviruses-from SARS and MERS to 2019-nCoV

Lee and Hsueh review the emergence of the zoonotic coronaviruses SARS, MERS, and 2019-nCoV. They provide a high level review of reservoirs, mechanisms of infection, routes of transmission, clinical presentation and pandemic potential, with an emphasis on using this information to inform current 2019-nCoV containment. Lee P-I and Hsueh P-R (Feb 4, 2020). Emerging threats…


A qualitative study of zoonotic risk factors among rural communities in southern China

In a qualitative evaluation of general zoonotic transmission risk factors in rural China, Li, et al. present information from predominantly agrarian communities. Interesting findings include: Dogs or cats kept for companionship, home protection or preventing rat infestations  Poultry, pigs and cattle raised for meat consumption; animal waste sometimes used as crop fertilizer; seeking medical treatment…


Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment

A case series of four 2019-nCoV pneumonia patients admitted to the Shanghai Public Health Clinical Center is presented. Patient recruitment was 21-24 Jan, and data collection occurred through 4 Feb, 2020.  All patients had mild to severe pneumonia with fever. Older patients were hospitalized for longer. Other symptoms, laboratory findings, and treatment regimens are summarized….


Preparation for Possible Sustained Transmission of 2019 Novel Coronavirus: Lessons From Previous Epidemics

Swerdlow and Finelli review information from modeling studies of earlier epidemics and pandemics to assess global preparedness for sustained transmission of an emerging viral disease with high transmissibility and severity. Examples cited were H1N1, SARS-CoV, and MERS-CoV.  Models suggest that:  Assuming no intervention in a US population, a model mixing a range of influenza transmission…


Transmission and epidemiological characteristics of Novel Coronavirus (2019-nCoV)-Infected Pneumonia (NCIP):preliminary evidence obtained in comparison with 2003-SARS

Updating a previously-posted pre-print, Zhang, et al. describe their analysis comparing 2019-nCoV pneumonia (NCIP) to 2003-SARS cases to guide prevention and control of the former. Data included public information on Chinese NCIP cases (n=287; age 9-90 years old; male:female ratio, 1.35:1). Compared to SARS, NCIP has a lower case fatality rate and a higher “cure…


The first 2019 novel coronavirus case in Nepal

Bastola, et al. provide a case report of the first confirmed 2019-nCoV case in Nepal. The case was a student in Wuhan returning to Nepal six days after symptom onset on 3 January, 2020. [Note: Potential inconsistency, implies that case left China on 9 Jan (by air) and arrived in Nepal on 13 Jan.] Case…


Transmission of 2019-nCoV infection from an asymptomatic contact in Germany

Rothe, et al. have provided supplementary information regarding their NEJM Correspondence from 31 January, 2020 that reported asymptomatic transmission between a Chinese business traveler and colleagues in Germany. This supplement follows news reports that Bavarian officials found the index case to be potentially symptomatic during her time in Germany. The supplement provides new detail on…


February 10, 2020

The mental health of medical workers in Wuhan, China dealing with the 2019 novel coronavirus

In this commentary, authors discuss the mental health effects experienced by medical workers in Wuhan during the current outbreak and the steps taken by local government and health care facility officials to support them.  Kang et al. (Feb 5, 2020). The mental health of medical workers in Wuhan, China dealing with the 2019 novel coronavirus….



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