Article Summary
March 30, 2021
Association of Race/Ethnicity With Likeliness of COVID-19 Vaccine Uptake Among Health Workers and the General Population in the San Francisco Bay Area
Black, Latinx, and Asian employees of three large medical centers in San Francisco had lower odds of reporting that they were likely to get vaccinated against COVID-19 compared to white employees in a cross-sectional study conducted from November 2020 to January 2021 (n=1,803). Compared to white respondents, Black, Asian and Latinx had 50%, 63%, and…
Dynamics of SARS-CoV-2 Neutralising Antibody Responses and Duration of Immunity: A Longitudinal Study
Five distinct patterns of SARS-CoV-2 neutralizing antibody dynamics were found in a longitudinal study of 164 SARS-CoV-2-infected patients in Singapore with follow-up of up to 180 days post-symptom onset. The different dynamics were defined by the trajectory by which antibody levels waned or evolved. Persistent dynamics, observed in the largest group of patients (32%), was…
Performance and Operational Feasibility of Antigen and Antibody Rapid Diagnostic Tests for COVID-19 in Symptomatic and Asymptomatic Patients in Cameroon: A Clinical, Prospective, Diagnostic Accuracy Study
A novel testing algorithm combining RT-PCR and antigen rapid diagnostic testing developed in Cameroon had 94% sensitivity and 91% specificity for detection of symptomatic SARS-CoV-2 infection within 7 days of symptom onset and outperformed PCR testing alone (75% sensitivity and 99% specificity). The algorithm was designed based on retrospectively performing 1000 simulation runs on empirical…
Preliminary Report on SARS-CoV-2 Spike Mutation T478K
[Pre-print, not peer-reviewed] A novel mutation (T478K) located on the SARS-CoV-2 spike protein was identified in an analysis of over 820,000 genomic sequences deposited on the global genome database GISAID up to March 26, 2021. Since its identification in the beginning of 2021, T478K is present in almost 2% of all sequenced genomes. Among the…
Successful Control of an Onboard COVID-19 Outbreak Using the Cruise Ship as a Quarantine Facility, Western Australia
Onboard quarantine measures to reduce the risk of a SARS-CoV-2 outbreak among crew members of the cruise ship MS Artania led to no symptomatic infections among crew members after completion of quarantine, despite an attack rate of 6% (30 of 503) before quarantine and 5% (21 of 441) during quarantine on board. The outbreak occurred…
COVID-19 Response Strategies at Large Institutes of Higher Education in the United States: A Landscape Analysis, Fall 2020
93% of the 50 largest public and 50 largest private US institutions of higher education offered some in-person teaching for the Fall 2020 semester, according to a landscape analysis of the COVID-19 response strategies. Among those offering some in-person teaching, 71% offered a hybrid reopening structure (≥25% students on campus). Among the 93 of institutions…
March 29, 2021
Years of Potential Life Lost Secondary to COVID-19: Cook County, Illinois
Among residents of Cook County, Illinois during the COVID-19 pandemic, the years of potential life lost (YPLL) was 4.8 times greater in the most affected racial/ethnic group (YPLL: 2289/100,000 population among Hispanic individuals) than in the least affected group (YPLL: 480/100,000 population among Asian individuals). 8,283 Cook County residents died from COVID-19 between March and…
Sudden Rise in COVID-19 Case Fatality among Young and Middle-Aged Adults in the South of Brazil after Identification of the Novel B.1.1.28.1 (P.1) SARS-CoV-2 Strain Analysis of Data from the State of Parana
[Pre-print, not peer-reviewed] An analysis of 553,518 cases of SARS-CoV-2 (8,853 fatal) between September 1, 2020 and March 17, 2021 in the Brazilian state of Parana found higher COVID-19 case fatality rates (CFRs) among nearly all age groups that coincided with local identification of the SARS-CoV-2 P.1 variant. All age groups showed either a decline…
Characterizing the Disproportionate Burden of SARS-CoV-2 Variants of Concern among Essential Workers in the Greater Toronto Area Canada
[Pre-print, not peer-reviewed] In the Greater Toronto Area, Canada, SARS-CoV-2 cases defined as variant of concern (VOC) emerged faster in groups with the lowest income (growth rate 43.8%, 34.6%, and 21.6% by income tertile from lowest to highest), and the most essential work (growth rate 18.4%, 30.8%, and 50.8% by essential work tertile from lowest…
Projected COVID-19 Epidemic in the United States in the Context of the Effectiveness of a Potential Vaccine and Implications for Social Distancing and Face Mask Use
A study developing a dynamic compartmental model of SARS-CoV-2 transmission in New York, Texas, Florida, and California showed that relaxing social distancing restrictions to pre-pandemic levels without changing current face mask use would lead to new outbreaks, resulting in 0.8–4 million infections and 15,000–240,000 deaths across these four states over the next 12 months. If face…
Previous page Next page