COVID-19 Literature Situation Report
COVID-19 Literature Situation Report is a daily (M-F) newsletter that provides a succinct summary of the latest scientific literature related to the COVID-19 pandemic.
The scientific literature on COVID-19 is rapidly evolving and these articles were selected for review based on their relevance to Washington State decision making around COVID-19 response efforts. Included in these Lit Reps are some manuscripts that have been made available online as pre-prints but have not yet undergone peer review. Please be aware of this when reviewing articles included in the Lit Reps.
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January 4, 2021
COVID-19 Literature Situation Report Jan 4, 2021

The Moderna vaccine mRNA-1273 showed 94.1% efficacy at preventing COVID-19, including severe disease, in a peer-review publication from the phase 3 trial. Efficacy was similar across key secondary analyses, and all severe cases of COVID-19 occurred in the placebo group.
December 30, 2020
COVID-19 LITERATURE SITUATION REPORT DEC. 30, 2020

A nationally representative longitudinal survey (n=8,167) found that self-reported likelihood of getting a COVID-19 vaccine declined from 74% in early April to 56% in early December. Significant declines in the likelihood of vaccine uptake were observed in all gender, age, racial/ethnic, and education subgroups.
December 28, 2020
COVID-19 LITERATURE SITUATION REPORT DEC. 28, 2020

Presence of anti-spike or anti-nucleocapsid IgG antibodies was associated with a reduced risk of SARS-CoV-2 reinfection among health care workers in the UK over 6 months of follow-up.
December 23, 2020
COVID-19 LITERATURE SITUATION REPORT DEC. 23, 2020

An investigation of the transmission of the mutated 501Y strain of SARS-CoV-2 circulating in the United Kingdom (UK) suggests that it may be 75% more transmissible than the previous lineage, but there does not appear to be significant spread outside of the UK despite sporadic cases in Wales, Australia, Spain, and the US.
December 21, 2020
COVID-19 LITERATURE SITUATION REPORT DEC. 21, 2020

The Advisory Committee on Immunization Practices issued an interim recommendation for use of the Moderna COVID-19 vaccine in persons aged ≥18 years for prevention of COVID-19 on December 19, 2020.
December 18, 2020
COVID-19 LITERATURE SITUATION REPORT DEC. 18, 2020

A randomized trial found that tocilizumab reduced the risk of mechanical ventilation but did not prevent deaths among patients with COVID-19 pneumonia
December 17, 2020
COVID-19 LITERATURE SITUATION REPORT DEC. 17, 2020

An interim analysis of the ongoing trial for the antibody cocktail REGN-COV2 among non-hospitalized COVID-19 patients (n=228) found a larger difference in viral loads (mean difference of -0.41 log10 copies per milliliter) among patients in treatment group compared to placebo group
December 16, 2020
COVID-19 LITERATURE SITUATION REPORT DEC. 16, 2020

The COVID-19 pandemic was associated with substantial increases in all-cause mortality among US adults aged 25-44 years from March to July of 2020. In multiple regions, deaths due to COVID-19 in this age range were similar to or exceeded unintentional opioid deaths that occurred during corresponding months in 2018.
December 15, 2020
COVID-19 LITERATURE SITUATION REPORT DEC. 15, 2020

Attending school or child care was not associated with receiving a positive SARS-CoV-2 test result among children and adolescents aged <18 years in Mississippi. By contrast, infection was more likely among children who had close contact with a person with COVID-19 and among those who attended gatherings with persons outside their household.
December 14, 2020
COVID-19 LITERATURE SITUATION REPORT DEC. 14, 2020

The US Advisory Committee on Immunization Practices issued an interim recommendation for use of the Pfizer-BioNTech COVID-19 vaccine in persons aged ≥16 years for the prevention of COVID-19.
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