Alliance for Pandemic Preparedness

COVID-19 Literature Situation Report

COVID-19 Literature Situation Report is a daily (M-F) newsletter that provides a succinct summary of the latest scientific literature related to the COVID-19 pandemic.

The scientific literature on COVID-19 is rapidly evolving and these articles were selected for review based on their relevance to Washington State decision making around COVID-19 response efforts. Included in these Lit Reps are some manuscripts that have been made available online as pre-prints but have not yet undergone peer review. Please be aware of this when reviewing articles included in the Lit Reps.

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December 11, 2020

COVID-19 LITERATURE SITUATION REPORT DEC. 11, 2020

School-based mitigation strategies recommended by CDC would cost an estimated 0.3% to 7.1% more than school expenditures reported by states in fiscal year 2018


December 10, 2020

COVID-19 LITERATURE SITUATION REPORT DEC. 10, 2020

Results of the phase 3 trial for the BioNTech and Pfizer vaccine BNT162b2 (n=21,720 in vaccine group, 21,728 in placebo group) showed a vaccine efficacy of 95%, with 8 cases of COVID-19 in the vaccine group and 162 cases in the placebo group after 2 doses.


December 9, 2020

COVID-19 LITERATURE SITUATION REPORT DEC. 9, 2020

Novel Coronavirus SARS-CoV-2

Following school reopening in England between June 1 and July 17, 2020, only 177 COVID-19 events were identified among 57,600 educational settings. Of these, 113 consisted of a single case, nine involved two or more cases that occurred close enough in time such that secondary infection was unlikely, and 55 involved outbreaks of at least two epidemiologically linked cases. There was a median of 1 secondary case in the outbreaks. The risk of an outbreak was positively associated with the level of community COVID-19 incidence.


December 8, 2020

COVID-19 LITERATURE SITUATION REPORT DEC. 8, 2020

An interim analysis of ongoing phase 2/3 trials for the Oxford–AstraZeneca vaccine ChAdOx1 nCoV-19 showed overall vaccine efficacy was 70.4%, with no COVID-19-related hospital admissions occurring in vaccine recipients and 10 occurring in the control group.


December 7, 2020

COVID-19 LITERATURE SITUATION REPORT DEC. 7, 2020

A meta-analysis found that of 213 SARS-CoV-2 transmission clusters from 12 countries, 3.8% had a pediatric index case. The secondary attack rate was lower among pediatric than adult household contacts (RR=0.62).


December 4, 2020

COVID-19 LITERATURE SITUATION REPORT DEC. 4, 2020

From March-August 2020, data from the COVID-NET indicated that more than 1 in 5 younger adults (ages 18-49) without underlying conditions who were hospitalized with COVID-19 in the US experienced severe illness requiring ICU-level care.


December 3, 2020

COVID-19 LITERATURE SITUATION REPORT DEC. 3, 2020

The Advisory Committee on Immunization Practices recommends that health care personnel and residents of long-term care facilities be offered COVID-19 vaccination in the initial phase of the US vaccination program


December 2, 2020

COVID-19 LITERATURE SITUATION REPORT DEC. 2, 2020

In Korea, reopening schools with good adherence to mitigation measures among students did not lead to significant increases in the proportion of pediatric cases with COVID-19 in the nation (7% by May 20 and 7.2% by July 31).


December 1, 2020

COVID-19 LITERATURE SITUATION REPORT DEC. 1, 2020

SARS-CoV-2 may have been introduced in the US earlier than previously recognized based on the detection of antibodies reactive to SARS-CoV-2 found in archived samples from routine blood donations in 9 states from December 2019 and January 2020.


November 30, 2020

COVID-19 LITERATURE SITUATION REPORT NOV. 30, 2020

A model estimating the societal and healthcare burdens of SARS-CoV-2 infections indicated that there were 2.4 million hospitalizations and 44.8 million symptomatic illnesses in the U.S. from February 27–September 30, 2020, yet only 1 of every 2.5 hospitalized infections and 1 of every 7.1 non-hospitalized illnesses may have been reported.



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