Alliance for Pandemic Preparedness

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Tag: children


May 18, 2021

Susceptibility and Infectiousness of Children and Adults with SARS-CoV-2 Variant B.1.1.7 Deduced from Three Daycare Centre Outbreaks and Related Household Situations Germany 2021

[Pre-print, not peer-reviewed] Secondary attack rates (SARs) were 17-37% in three kindergarten schools in Germany during three SARS-CoV-2 outbreaks likely caused by the B.1.1.7 variant. A majority (>80%) of secondary cases occurred within 7 days. The pooled household SAR was 37% after excluding single-occupant households and households with another possible index case. Notably, the attack…


May 17, 2021

A Retrospective Cohort Study of 12,306 Pediatric COVID-19 Patients in the United States

A retrospective cohort study found that among 12,306 pediatric patients with lab-confirmed COVID-19 in the US, 5% were hospitalized, 18% needed critical care services and 4% required mechanical ventilation. 14% experienced gastrointestinal symptoms, 8% had dermatological symptoms (rash), 5% had headache, and 19% had other symptoms (fever, malaise, myalgia, arthralgia and altered smell or taste)….


Asymptomatic SARS-CoV-2-Infected Children Attending Hospital with Non-COVID-19 Diagnoses, March 2020-February 2021

A surveillance study conducted between March 1, 2020 and February 21, 2021 in the UK found that out of 1,427 pediatric patients admitted to the hospital, 80 (5.6%) tested positive for SARS-CoV-2, of which 52 (65%) had symptoms compatible with COVID-19, 16 (20%) were asymptomatic, and 12 (15%) were “unclear” because of overlapping symptoms between…


May 14, 2021

Trends in Pediatric Primary Care Visits during the COVID-19 Pandemic

A retrospective review of a large US commercial medical claims database found that pediatric primary care visits were 60% lower between March 25 and April 21, 2020 compared to the same period in 2019, and problem-focused visits were 63% lower. Primary care visits and problem-focused visits remained 17% and 31% lower in October 2020 compared…


Trajectories of Child Emotional and Behavioural Difficulties before and during the COVID-19 Pandemic in a Longitudinal UK Cohort

[Pre-print, not peer-reviewed] Emotional and behavioral difficulties decreased at a slower rate during the COVID-19 pandemic among young children in the UK (N=708) in a longitudinal birth-cohort study. In pre-pandemic times, predicted trajectories of difficulties peaked at age 2 and declined over the rest of early childhood. During the pandemic, the rate of decline was…


Plans to Vaccinate Children for COVID-19 a Survey of US Parents

[Pre-print, not peer-reviewed] A national online survey of US parents (N=2,074) conducted in March 2021 found that 49% planned to vaccinate their children for COVID-19 when available, while 26% of respondents said they would “definitely not” vaccinate their children. The most common concerns cited about vaccines were safety, effectiveness, and a perceived lack of need….


May 6, 2021

SARS-CoV-2 Viral Load Kinetics in Symptomatic Children, Adolescents and Adults

Mean viral load (VL) was slightly lower at the time of SARS-CoV-2 infection diagnosis for children aged 0-13 years (6.2 log10 copies/mL) and adolescents aged 14-19 years (6.4 log10 copies/mL) compared to adults aged  ≥20 years (6.7 log10 copies/mL) in a study in Switzerland (n=8,027). At time of diagnosis, the proportion of adults with VL…


May 4, 2021

Clinical Characteristics and Transmission of COVID-19 in Children and Youths During 3 Waves of Outbreaks in Hong Kong

Among 397 individuals aged ≤18 years with confirmed COVID-19 during the first 3 waves in Hong Kong (January to December 2020), imported infections comprised 79% and 93% of all cases during the first and second wave, respectively, but domestic infections comprised 73% of all cases during the third wave. Overall among domestic infections, 91% had…


May 3, 2021

US Pediatric Emergency Department Visits for Mental Health Conditions During the COVID-19 Pandemic

A study of pediatric emergency department (ED) mental health (MH) visits found that although the mean number of monthly visits significantly decreased during the COVID-19 pandemic (from 339 to 261 visits per month), the proportion of ED visits for MH conditions significantly increased (from 4.0% to 5.7%). Data were collected from electronic medical records of…


Lower Household Transmission Rates of SARS-CoV-2 from Children Compared to Adults

The household secondary attack rate (SAR = 0.15) among pediatric index cases under age 18 (n = 17) was significantly lower than the rate among 126 adult (SAR = 0.38) index cases, according to findings from a seroprevalence study among 150 households in Germany with at least one confirmed case of SARS-CoV-2 since June 2020….



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