Alliance for Pandemic Preparedness

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Tag: children


February 16, 2021

Trends in US Pediatric Hospital Admissions in 2020 Compared With the Decade Before the COVID-19 Pandemic.

US pediatric hospital admissions in the US were lower in 2020 compared to the past 10 years, according to a cross-sectional study of over 5 million US pediatric hospital admissions at 49 hospitals in the Pediatric Health Information Systems database. There was a decrease in the number of admissions beginning in March 2020 compared with…


February 9, 2021

SARS-CoV-2 Transmission among Children and Staff in Daycare Centres during a Nationwide Lockdown in France: A Cross-Sectional, Multicentre, Seroprevalence Study

Children (n=327) and staff (n=197) attending daycare centers in France during the lockdown from March to May 2020 had similar seroprevalence (4% and 7%, respectively) to a comparator group consisting of laboratory or administrative personnel not occupationally exposed to COVID-19 patients or children (5%). In addition, seropositive children were 7-times as likely to have been…


February 5, 2021

Nasopharyngeal SARS-CoV-2 viral loads in young children do not differ significantly from those in older children and adults

A multicenter study of SARS-CoV-2 cases (n=5,544) confirmed by RT-PCR assay found no significant differences in viral concentration (as measured by Ct values) across different age groups. In particular, the children less than 5 years old did not display higher nasopharyngeal viral loads than older children or adults. Madera et al. (Feb 4, 2021). Nasopharyngeal…


February 1, 2021

New Guidelines for Children Returning to Sports after Covid-19

The American Academy of Pediatrics updated guidelines December 17, 2020 for children returning to athletic activities, including recommendations for cloth face mask use during all indoor sports, except for swimming and diving, cheerleading, gymnastics, and wrestling. Cloth masks are also recommended for people on the sidelines, in locker rooms, and in training sessions. The guidelines…


January 25, 2021

Prevalence of SARS-CoV-2 Infection in Children and Their Parents in Southwest Germany

A multicenter, cross-sectional study of SARS-CoV-2 seroprevalence among children aged 1-10 years (n=2,482) in Germany and a corresponding parent (n=2,482) found that between April 22 and May 15 2020, the estimated seroprevalence was low in parents (1.8%) and 3-fold lower in children (0.6%). Only two participants (0.04%) tested positive for SARS-CoV-2 RNA. Among 56 families…


January 22, 2021

Demographic Predictors of Hospitalization and Mortality in US Children with COVID-19

Although deaths and hospitalizations are rare among children in the United States diagnosed with COVID-19, Black and multiracial children are more likely than white children to be hospitalized (OR=1.5) and die (OR=3.0). Children with a prior medical condition are also more likely to be hospitalized (OR=3.6) and to die (OR=8.8). Of the 27,045 children whose…


January 21, 2021

Saliva Viral Load Better Correlates with Clinical and Immunological Profiles in Children with Coronavirus Disease 2019

Among 91 pediatric COVID-19 patients (<18 years) admitted to a hospital in Hong Kong, SARS-CoV-2 viral loads from saliva correlated better with clinical and immunological profiles than viral loads from nasopharyngeal swabs (NPS). Patients with cough, sputum production, and headache had significantly higher saliva, but not NPS, viral loads. Higher saliva, but not NPS, viral…


January 19, 2021

Secondary Attack Rate in Household Contacts of COVID-19 Paediatric Index Cases: A Study from Western India

A cross-sectional study in Western India estimated a SARS-CoV-2 household attack rate from pediatric index cases of 2%, based on 72 pediatric index COVID-19 cases and 287 household contacts. Index cases were mostly male (94%) and between the ages of 12-18 (74%). Households of index cases with secondary infections were larger than those without secondary…


January 12, 2021

Trends in Pediatric Hospitalizations for Coronavirus Disease 2019

Rates of pediatric hospitalization for COVID-19 showed significant variation across 22 states from May to November 2020. In May, Hawaii and Rhode Island had the lowest pediatric hospitalization rates (0 per 100,000) while New Jersey and Colorado had the highest (5 and 4.4 per 100,000 children, respectively). In November, Hawaii and New Hampshire had the…


January 4, 2021

Longitudinal Testing for Respiratory and Gastrointestinal Shedding of SARS-CoV-2 in Day Care Centres in Hesse, Germany

A longitudinal study of children (n=859, age 3 months – 8 years) and staff (n=376) from daycare centers in Germany conducted from June-September 2020 found that detection of either respiratory or gastrointestinal shedding of SARS-CoV-2 RNA was rare in the context of limited community activity and with facility-based infection prevention measures. Of 7,366 buccal mucosa…



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