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Tag: children
October 14, 2020
Risk Factors for Re-Detectable Positivity in Recovered COVID-19 Children
In a healthcare setting in China where two negative PCR tests for SARS-Cov-2 were required for hospital discharge, 37% of pediatric patients (n=14) had positive PCR tests upon subsequent PCR testing (“re-detectable positivity”). Family cluster infection, higher white blood cell count, and longer plasma prothrombin time were identified as risk factors for re-detectable positivity. In…
October 9, 2020
Characteristics of Hospitalized Children With SARS-CoV-2 in the New York City Metropolitan Area
Children with comorbidities who were hospitalized with SARS-CoV-2 were at increased risk for critical care admission and/or need for respiratory support, based on results from a multicenter, retrospective cohort study at four hospitals in the New York City metropolitan area. Obesity was the most commonly observed risk factor for critical care (63% vs. 28%), while…
Children and Adolescents With SARS-CoV-2 Infection
A study of 203 children infected with SARS-CoV-2 indicated that infection is typically asymptomatic or mild during childhood, and that most children have moderate or high viral loads regardless of age, symptoms, or severity of infection. Among children for whom the source of infection was identified, 74% were infected by a member of their household. In 67% of…
October 2, 2020
Increased Proportion of Physical Child Abuse Injuries at a Level I Pediatric Trauma Center during the Covid-19 Pandemic
The proportion of patients treated for traumatic injuries caused by physical child abuse at the Johns Hopkins Children’s Center during the COVID-19 pandemic was significantly higher compared to the previous two years. During the COVID-19 period, the median age of patients with injuries due to physical child abuse was 11.5 months, and 38% were male….
Sequelae of COVID-19 in Hospitalized Children
A study of 28 hospitalized pediatric patients with COVID-19 in Turin, Italy found that all participants had nasal swabs negative for SARS-CoV-2 by PCR one month after discharge. Lung ultrasound findings had normalized within 5 weeks from hospital discharge in the majority of patients. 20 out of 24 patients developed anti-SARS-CoV-2 IgG at the follow-up…
October 1, 2020
National Trends of Cases of COVID-19 in Children Based on US State Health Department Data
As of Sept 10, 2020, there were 549,432 cumulative COVID-19 cases in the US among children (729 cases per 100,000 children). The geographic focus of case growth shifted from the Northeast in April to the South and West in June and to the Midwest in July. Over time, the proportion of pediatric COVID-19 cases has…
September 2, 2020
Serological Identification of SARS-CoV-2 Infections among Children Visiting a Hospital during the Initial Seattle Outbreak
Six of eight children who had SARS-CoV-2 antibodies detected in leftover clinical samples had not been suspected of having COVID-19. Dingens et al. screened 1,775 leftover serum samples from children seeking medical care at Seattle Children’s Hospital during the early Seattle outbreak period and found one child was seropositive with SARS-CoV-2 in March and seven…
August 26, 2020
Diagnosis of SARS-CoV-2 in Children Accuracy of Nasopharyngeal Swab Compared to Nasopharyngeal Aspirate
[pre-print, not peer-reviewed] Comparing the diagnostic performance of nasopharyngeal swab (NS) to nasopharyngeal aspirate (NPA) for the detection of SARS-CoV-2 in children (n=300 paired samples), NS was found to have a low sensitivity in detecting SARS-CoV-2 in children when referred to NPA. The authors recommend that in children under 6 years of age, NS should…
August 24, 2020
SARS-CoV-2 Infections Among Children in the Biospecimens from Respiratory Virus-Exposed Kids (BRAVE Kids) Study
[pre-print, not peer-reviewed] In a cohort of children and adolescents who had close contact with a person with known SARS-CoV-2 infection (n=382), SARS-CoV-2-infected children (n=293) were more likely to be Hispanic (88% vs 57%), less likely to have asthma (6% vs 17%), and more likely to have an infected sibling contact (49% vs 29%), compared…
August 21, 2020
Limited Secondary Transmission of SARS-CoV-2 in Child Care Programs — Rhode Island
• Link-Gelles et al. report 52 confirmed and probable childcare-associated cases of COVID-19 in 29 childcare programs in the state of Rhode Island in the two months following reopening of childcare programs on June 1. Of the cases, 30 (58%) were among children (median age = 5 years), and 22 (42%) were among adults (20…
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