Result for
Tag: geographic spread
January 14, 2021
Earliest Detection to Date of SARS-CoV-2 in Florida: Identification Together with Influenza Virus on the Main Entry Door of a University Building, February 2020
A sample collected from a door handle on February 21, 2020 in an influenza surveillance study in Florida tested positive for SARS-CoV-2 RNA, despite the first official case of COVID-19 in the state not being reported until March 1, 2020. Sequence analysis found that the Florida SARS-CoV-2 strain, UF-11, was identical to strains identified in…
December 1, 2020
Serologic Testing of U.S. Blood Donations to Identify SARS-CoV-2-Reactive Antibodies: December 2019-January 2020
Analysis of archived samples from routine Red Cross blood donations collected December 13, 2019 to January 17, 2020 from donors in nine states, including Washington, suggests SARS-CoV-2 was introduced in the US prior to the first identified case in January 19, 2020. Among 7,389 samples, 106 contained antibodies reactive to the SARS-CoV-2 spike protein and…
November 24, 2020
SARS-CoV-2 Seroprevalence Worldwide: A Systematic Review and Meta-Analysis
A pooled estimate of global SARS-CoV-2 seroprevalence was 3.4% in a systematic review and meta-analysis (n=47 studies) of data from 23 countries published through August 2020. Seroprevalence in general population studies varied from 0.4% to 22%. The lowest regional seroprevalence was observed in South America (1.5%), while the highest was in Northern Europe (5%). The…
November 19, 2020
Global Seroprevalence of SARS-CoV-2 Antibodies a Systematic Review and Meta-Analysis
[Pre-print, not peer reviewed] In a systematic review and meta-analysis of 338 seroprevalence studies representing 50 countries and 2.3 million participants, global SARS-CoV-2 seroprevalence in the general population was low (median 3.2%, IQR 1.0-6.4%) through August 2020, suggesting that most of the population still remains susceptible to infection. Seroprevalence was higher among Black and Asian…
November 13, 2020
The Change in Seroprevalence in the US plus Puerto Rico between May and September of SARS-CoV-2 Antibody in the Asymptomatic Population
[Pre-print, not peer-reviewed] The prevalence of SARS-CoV-2 antibodies among asymptomatic individuals in the US more than doubled during May to September (3.0% to 6.6%), with the greatest increase observed in younger individuals (< age 20, 7.8%). Antibody prevalence was similar among males and females, but varied by age. Based on the September prevalence, there were…
November 12, 2020
Large Scale Genomic Analysis of 3067 SARS-CoV-2 Genomes Reveals a Clonal Geo-Distribution and a Rich Genetic Variations of Hotspots Mutations
A large-scale analysis of 3067 SARS-CoV-2 genomes from 55 countries tracked mutations within the virus genome and identified three major clades in various geographic regions. The analysis also revealed geographic mutation hotspots – in particular, China, the US, France, and Malaysia – contained a high number of specific mutations. The authors note the high number…
November 5, 2020
Revealing Fine-Scale Spatiotemporal Differences in SARS-CoV-2 Introduction and Spread
Analysis of 247 SARS-CoV-2 sequences from two nearby communities in Wisconsin illustrate distinct patterns of viral spread. Though Dane County had the 12th known introduction of SARS-CoV-2 in the US, this did not lead to community spread. 60 miles away, Milwaukee County experienced few introductions followed by extensive community spread. Moreno et al. (Nov 3,…
November 4, 2020
They’re Dying in the Suburbs COVID-19 Cases and Deaths by Geography in Louisiana (USA)
[Preprint, not peer-reviewed] The epicenter of the Louisiana COVID-19 epidemic has varied temporally, beginning in the urban core of New Orleans and then moving to suburban/rural areas. Using census tract- and parish-level data in Louisiana, Schnake-Mahl et al. reported that the incidence (73 cases per 10,000) and mortality rate (5.6 deaths per 10,000) of COVID-19…
November 3, 2020
Age-Specific Mortality and Immunity Patterns of SARS-CoV-2
Using age-specific COVID-19 death data and seroprevalence studies, the age distribution of deaths among those <65 years old was consistent across 45 countries. The infection fatality ratio (IFR) was estimated to be the lowest among children aged 5-9 years old (0.001%) and increased with age. The highest IFR was observed among those 80+ (8.3%). Mortality…
October 1, 2020
SARS-CoV-2 Seroprevalence among a Southern U.S. Population Indicates Limited Asymptomatic Spread under Physical Distancing Measures
The seroprevalence of anti-SARS-CoV-2 IgG among people accessing health care for reasons other than COVID-19 symptoms in a low-density, suburban and rural population in North Carolina was 0.8% (24 of 2973) of outpatients and 0.7% (10 of 1449) of inpatients. Participants were sampled between March and June 2020, when state restrictions and physical distancing mandates…
Previous page Next page