Result for
Tag: risk factors
February 19, 2021
COVID-19 Prevalence and Mortality Among Schizophrenia Patients: A Large-Scale Retrospective Cohort Study
A large-scale retrospective cohort study in Israel found that individuals with schizophrenia (n = 25,539) were twice as likely to be hospitalized for COVID-19 (OR = 2.2), even after controlling for sociodemographic and clinical risk factors (OR = 1.9). They were also three times more likely to experience COVID-19 mortality (OR = 3.3) compared to…
HIV-1 Infection Does Not Change Disease Course or Inflammatory Pattern of SARS-CoV-2-Infected Patients Presenting at a Large Urban Medical Center in New York City
People living with HIV (PWH) with COVID-19 were more likely to be admitted from the emergency department when compared to patients without HIV (91% vs 71%), according to a retrospective cohort study in New York. After admission, there was no statistically significant difference in 30-day mortality rate or mechanical ventilation rate. Clinical characteristics, including age,…
February 18, 2021
Surge Effects and Survival to Hospital Discharge in Critical Care Patients with COVID-19 during the Early Pandemic: A Cohort Study
The odds of surviving to hospital discharge among critical COVID-19 patients increased over time in a retrospective cohort study (n=620) in the western US from February to May 20. Overall, 403 (65%) patients were discharged alive, increasing from 60% to 68% between the first 2 weeks of the study period to the last 2 weeks….
February 3, 2021
Gastroenterology Manifestations and COVID-19 Outcomes: A Meta-Analysis of 25,252 Cohorts among the First and Second Waves
Twenty percent of COVID-19 patients presented with GI symptoms, according to a meta-analysis. In 125 studies included in the analysis, GI symptoms upon presentation to care included loss of appetite (20%), altered sense of taste or loss of taste (15%), diarrhea (13%), nausea (10%), and vomiting of blood (9%). Over 26% of patients had confirmed…
February 2, 2021
Genetically Predicted Serum Vitamin D and COVID-19 a Mendelian Randomization Study
[Pre-print, not peer reviewed] Long-term vitamin D nutritional status does not causally affect susceptibility to SARS-CoV-2 infection or more severe COVID-19 disease course, according to a two-sample Mendelian randomization study of a European cohort. No elevation in the risk of COVID infection, hospitalization, or progression to severe COVID-19 was associated with serum vitamin D status…
February 1, 2021
Pre-Pandemic Psychiatric Disorders and Risk of COVID-19: A UK Biobank Cohort Analysis
A cohort study using data from the UK Biobank and Public Health England found an increased risk of COVID-19 infection (OR = 1.44), hospitalization (OR = 1.55), and death (OR = 2.03) among individuals with psychiatric conditions diagnosed before the pandemic, including depression, stress-related disorder, and substance use. The associations were stronger among individuals who…
January 27, 2021
A Higher BMI Is Not Associated with a Different Immune Response and Disease Course in Critically Ill COVID-19 Patients
Among patients with COVID-19 in The Netherlands who required mechanical ventilation in the ICU, higher BMI was not associated with differences in measurements of plasma cytokines or clinical outcomes. Patients (n=67) were classified as obese (BMI ≥30 kg/m2) and non-obese (BMI <30 kg/m2). Obese participants had a lower elevation in body temperature (38.1C vs. 38.7C) but no other clinical…
January 26, 2021
Association of Smoking and Cumulative Pack-Year Exposure With COVID-19 Outcomes in the Cleveland Clinic COVID-19 Registry
Greater pack-years of smoking was associated with worse COVID-19 outcomes in a cohort of 7,102 SARS-CoV-2 positive patients with full smoking information. Patients who smoked between 10-30 pack years had 1.4-times the odds of hospitalization compared to never smokers, while patients who smoked more than 30 pack-years had 2.3 -times the odds of hospitalization and…
January 22, 2021
A Cross-Sectional Analysis of Demographic and Behavioral Risk Factors of SARS-CoV-2 Antibody Positivity among a Sample of U.S. College Students
[pre-print, not peer-reviewed] Among undergraduate students at a single college in Indiana, fraternity or sorority membership, having multiple romantic partners, knowing someone with COVID-19, drinking alcohol more than 1 day per week, and attending social gatherings with more than 4 people when drinking alcohol increased both the likelihood of seropositivity and self-reported history of SARS-CoV-2….
January 21, 2021
Association of Social and Economic Inequality With Coronavirus Disease 2019 Incidence and Mortality Across US Counties
A cross-sectional ecologic analysis using US county-level data found that counties with higher income inequality and a higher proportion of Black or Hispanic residents had higher COVID-19 incidence and mortality. Each 1% increase in county-level income inequality, proportion of Black residents, and proportion of Hispanic residents corresponded to 2%, 1.9%, and 2.4% higher incidence and…
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