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Tag: risk factors
January 14, 2021
Testing, Infection and Complication Rates of COVID-19 among People with a Recent History of Homelessness in Ontario, Canada: A Retrospective Cohort Study
A population-based retrospective cohort study in Ontario, Canada (n=29,407) found that compared to community-dwelling people, people with a recent history of homelessness were more likely to be tested for SARS-CoV-2 and to have a positive test result during the pre-shutdown, peak, and reopening phases of the pandemic. During the peak period, people with a recent…
Sleep Apnoea Is a Risk Factor for Severe COVID-19
A nationwide retrospective study in Finland (n=260,405) found that while obstructive sleep apnea (OSA) was not associated with a COVID-19 diagnosis, OSA was associated with COVID-19 hospitalization (aOR=2.93) after adjusting for age, sex, BMI, and comorbidities. A separate meta-analysis including other published studies found a pooled OR estimate of 1.55. Strausz et al. (Jan 12,…
January 11, 2021
Impact of Tobacco Smoking on the Risk of COVID-19
A cross-sectional study of sailors on a navy aircraft carrier (n=1688, 87% male) found that current smoking status was associated with a lower risk of COVID-19 (OR = 0.59). 1279 (76%) crewmembers developed COVID-19 (62% RT-PCR positive, 14% with only clinical signs), and crewmembers >50 years old had an increased risk of contracting COVID-19 (OR…
January 5, 2021
Accuracy of the Veterans Health Administration COVID-19 (VACO) Index for Predicting Short-Term Mortality among 1307 Yale New Haven Hospital Inpatients and 427224 Medicare Patients
[Pre-print, not peer reviewed] The Veterans Health Administration COVID-19 (VACO) Index was shown to accurately estimate risk of short-term mortality among a wide variety of patients. The index was validated using 1,307 Yale New Haven Hospital inpatients and over 420,000 Medicare patients and consistently identified those at greatest relative risk of death. The authors suggest…
January 4, 2021
Mortality in Hospitalized Patients with Cancer and Coronavirus Disease 2019: A Systematic Review and Meta‐analysis of Cohort Studies
A systematic review and meta-analysis of the effects of COVID-19 on the clinical outcomes of patients with cancer indicated that the pooled 30‐day mortality rate from 13 primarily inpatient studies (n=2922 patients) was 30%. The overall pooled 30‐day mortality risk from 5 studies that included a mixture of inpatient and outpatient populations (n=624 patients) was…
December 30, 2020
Association of Substance Use Disorders and Drug Overdose with Adverse COVID-19 Outcomes in New York City: January–October 2020
A history of substance use disorder (SUD) and drug overdose is a risk factor for adverse outcomes in patients diagnosed with COVID-19 in New York City. In a retrospective review of the medical records from 188,653 patients diagnosed with COVID in the NYU system, both SUD and drug overdose were associated with hospitalization, ICU admission,…
Previous Dengue Infection and Mortality in COVID-19
In a prospective study of 2,351 people with COVID-19 SARS in Brazil, those with previous symptomatic dengue (n=1177) had a lower risk of death after a median follow-up of 60 days (adjusted HR = 0.44). History of other previous infections, including malaria, Zika, and chikungunya, were not associated with mortality. The authors suggest that dengue…
Immune Deficiency Is a Risk Factor for Severe COVID‐19 in People Living with HIV
Among 175 people living with HIV in the UK, US, and Spain, a current CD4 T-cell count of <350 cells/µL was independently associated with a 2.85-fold risk for developing severe COVID-19. A lower nadir CD4 T-cell count of <200 cells/µL was associated with mortality. No significant differences in risk of severe or critical COVID-19 were…
December 21, 2020
Risk Factors for SARS-CoV-2 Seropositivity in a Health Care Worker Population
[Pre-print, not peer-reviewed] Risk factors for seropositivity among hospital workers (n = 1,557, seropositivity 10.8%) at an academic medical center in California were male gender, exposure to COVID-19 outside of work, working in food or environmental services, and working in COVID-19 units. Seropositive HCWs who were missed by occupational screening were more likely to be…
December 18, 2020
Analyses of Abdominal Adiposity and Metabolic Syndrome as Risk Factors for Respiratory Distress in COVID-19
A prospective observational cohort study in the Netherlands indicated that abdominal adiposity was an independent risk factor for respiratory distress in patients with COVID-19 when adjusted for metabolic syndrome, age, gender and BMI (aOR=1.11). Among 86 patients with COVID-19, the prevalence of metabolic syndrome did not differ between patients with or without the need for…
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